Patents by Inventor Faraz A. Choudhury

Faraz A. Choudhury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and systems for transmission and detection of free radicals
    Patent number: 12247920
    Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
    Type: Grant
    Filed: February 27, 2023
    Date of Patent: March 11, 2025
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: J. Leon Shohet, Michael R. Sussman, Faraz A. Choudhury, Benjamin B. Minkoff, Grzegorz Sabat, Joshua M. Blatz
  • COMPOSITIONS AND METHODS FOR PLIMB-MEDIATED RADICAL LABELING IN VIVO
    Publication number: 20250076297
    Abstract: Provided herein are materials and methods for in vivo labeling of membrane proteins using plasma-induced modification of biomolecules (PLIMB).
    Type: Application
    Filed: August 28, 2024
    Publication date: March 6, 2025
    Inventors: Daniel Benjamin, Faraz Choudhury, Jonathan Schmitz, James Dowell, Alexis Lawton, Samantha Knott
  • COMPOSITIONS AND METHODS FOR PLASMA-FREE TRIFLUOROMETHYL AND HYDROXYL RADICAL LABELING
    Publication number: 20250076308
    Abstract: Provided herein are materials and methods for plasma-free labeling of biological molecules with trifluoromethyl and hydroxyl radicals generated using a peroxide and a radical precursor such as sodium triflinate. The methods provided herein find use in labeling of molecules, such as cell-membrane proteins, in live, intact cells.
    Type: Application
    Filed: September 6, 2024
    Publication date: March 6, 2025
    Inventors: Daniel Benjamin, Faraz Choudhury, Jonathan Schmitz, James Dowell, Alexis Lawton, Samantha Knott, Patric Sadecki
  • COMPOSITIONS AND METHODS FOR MULTIPLEXED PLIMB-MEDIATED RADICAL LABELING
    Publication number: 20240400609
    Abstract: Provided herein are materials and methods for plasma-based multiplexed labeling of biological molecules. In some aspects, provided herein is an optimized method for simultaneous labeling of proteins with trifluoromethyl, nitro, and hydroxyl radicals generated by a plasma in a single reaction vial, such as for protein footprinting.
    Type: Application
    Filed: May 31, 2024
    Publication date: December 5, 2024
    Inventors: Samantha Knott, Daniel Benjamin, Faraz Choudhury, James Dowell
  • METHODS AND SYSTEMS FOR TRANSMISSION AND DETECTION OF FREE RADICALS
    Publication number: 20230375474
    Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
    Type: Application
    Filed: February 27, 2023
    Publication date: November 23, 2023
    Inventors: J. Leon Shohet, Michael R. Sussman, Faraz A. Choudhury, Benjamin B. Minkoff, Grzegorz Sabat, Joshua M. Blatz
  • METHODS, SYSTEMS, AND COMPOSITIONS FOR STUDYING SOLVENT ACCESSIBILITY AND THREE-DIMENSIONAL STRUCTURE OF BIOLOGICAL MOLECULES
    Publication number: 20230061431
    Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
    Type: Application
    Filed: April 8, 2022
    Publication date: March 2, 2023
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Michael R. Sussman, J. Leon Shohet, Faraz A. Choudhury, Joshua M. Blatz, Benjamin B. Minkoff, Daniel I. Benjamin
  • Methods and systems for transmission and detection of free radicals
    Patent number: 11592394
    Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: February 28, 2023
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: J. Leon Shohet, Michael R. Sussman, Faraz A. Choudhury, Benjamin B. Minkoff, Grzegorz Sabat, Joshua M. Blatz
  • Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules
    Patent number: 11300562
    Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: April 12, 2022
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Michael R. Sussman, J. Leon Shohet, Faraz A. Choudhury, Joshua M. Blatz, Benjamin B. Minkoff, Daniel I. Benjamin
  • METHODS, SYSTEMS, AND COMPOSITIONS FOR STUDYING SOLVENT ACCESSIBILITY AND THREE-DIMENSIONAL STRUCTURE OF BIOLOGICAL MOLECULES
    Publication number: 20200150106
    Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 14, 2020
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Michael R. Sussman, J. Leon Shohet, Faraz A. Choudhury, Joshua M. Blatz, Benjamin B. Minkoff, Daniel I. Benjamin
  • Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules
    Patent number: 10571460
    Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: February 25, 2020
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Michael R. Sussman, J. Leon Shohet, Faraz A. Choudhury, Joshua M. Blatz, Benjamin B. Minkoff, Daniel I. Benjamin
  • METHODS AND SYSTEMS FOR TRANSMISSION AND DETECTION OF FREE RADICALS
    Publication number: 20180045645
    Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
    Type: Application
    Filed: August 14, 2017
    Publication date: February 15, 2018
    Inventors: J. Leon Shohet, Michael R. Sussman, Faraz A. Choudhury, Benjamin B. Minkoff, Grzegorz Sabat, Joshua M. Blatz
  • METHODS, SYSTEMS, AND COMPOSITIONS FOR STUDYING SOLVENT ACCESSIBILITY AND THREE-DIMENSIONAL STRUCTURE OF BIOLOGICAL MOLECULES
    Publication number: 20170336390
    Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
    Type: Application
    Filed: May 19, 2017
    Publication date: November 23, 2017
    Inventors: Michael R. Sussman, J. Leon Shohet, Faraz A. Choudhury, Joshua M. Blatz, Benjamin B. Minkoff, Daniel I. Benjamin