Patents by Inventor Fardous F. El-Senduny

Fardous F. El-Senduny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoformulation of spriooxindole and methods for treating hepatocellular carcinoma
    Patent number: 11944604
    Abstract: A spirooxindole nanoformulation includes a proniosome loaded with a spirooxindole derivative.
    Type: Grant
    Filed: March 10, 2023
    Date of Patent: April 2, 2024
    Assignee: KING SAUD UNIVERSITY
    Inventors: Assem Barakat, Fardous F. El-Senduny, Mohammad Shahidul Islam, Abdullah Mohammed Al Majid, Yaseen Ali Mosa Mohamed Elshaier, Eman Ahmed Ibrahim Mazyed, Farid A. Badria
  • Substituted spirooxindoles
    Patent number: 9822128
    Abstract: The substituted spirooxindoles are MDM2-p53 inhibitors bearing a benzylidine (styryl) arm and have a complex fused ring system ideally suited for binding to the MDM2 protein, thereby interrupting its protein-protein interaction (PPI). Sixteen compounds, designated 4a-4p, were synthesized in a simple smooth method using an asymmetric 1,3-dipolar reaction as the key step. Testing showed that the compounds exhibit anti-cancer activity against various forms of cancer cells affecting humans.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: November 21, 2017
    Inventors: Assem Barakat, Mohammad Shahidul Islam, Abdullah Mohammed Al Majid, Hussain Mansur Ghawas, Fardous F. El-Senduny, Farid A. Badria, Yaseen Ali Mosa Mohamed Elshaier, Hazem A. Ghabbour