Patents by Inventor Farha KHAN

Farha KHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND USES THEREOF
    Publication number: 20230066315
    Abstract: Compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: January 17, 2020
    Publication date: March 2, 2023
    Inventors: Son Minh PHAM, Jayakanth KANKANALA, Pradeep S. JADHAVAR, Baban Mohan MULIK, Farha KHAN, Sreekanth A. RAMACHANDRAN
  • COMPOUNDS AS LXR AGONISTS
    Publication number: 20220363662
    Abstract: The present invention generally discloses compounds having LXR (the liver X receptor) agonistic activity, to the use of such compounds in the treatment of various disorders such as proliferative disorders, Alzheimer's disease, inflammatory diseases, and diseases characterized by defects in cholesterol and lipid metabolism. Specifically, the present invention discloses compound of formula (IA) which exhibit LXR agonist activity, specifically to LXR?. The invention also discloses method of synthesis of said compounds, method of using said compounds, pharmaceutical compositions comprising said compounds and method of using thereof.
    Type: Application
    Filed: April 20, 2022
    Publication date: November 17, 2022
    Inventors: Brahmam Pujala, Balaji Dashrath Sathe, Abhinandan Danodia, Ashu Gupta, Sanjeev Soni, Vivek Kumar, Amantullah Ansari, Farha Khan, Arindam Sarkar, Pavan V. Payghan
  • HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
    Publication number: 20220298142
    Abstract: 5,6-disubstituted 2-aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: March 2, 2022
    Publication date: September 22, 2022
    Inventors: Son Minh PHAM, Jayakanth KANKANALA, Pradeep S. JADHAVAR, Baban Mohan MULIK, Farha KHAN, Sreekanth A. RAMACHANDRAN
  • 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF
    Publication number: 20220220111
    Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: December 13, 2021
    Publication date: July 14, 2022
    Inventors: Son Minh Phan, Jiyun Chen, Amantullah Ansari, Pradeep S. Jadhavar, Varshavekumar S. Patil, Farha Khan, Sreekanth A. Ramachandran, Anil Kumar Agarwal, Sarvajit Chakravarty
  • 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF
    Publication number: 20220169648
    Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: February 18, 2022
    Publication date: June 2, 2022
    Inventors: Son Minh PHAM, Jayakanth KANKANALA, Pradeep S. JADHAVAR, Baban Mohan MULIK, Farha KHAN, Sreekanth A. RAMACHANDRAN
  • ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF
    Publication number: 20220135598
    Abstract: The present invention discloses compounds useful in treatment of conditions associated with dysfunction of ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) enzyme. Specifically, the present invention discloses compound of formula (J) which exhibit inhibitory activity against ENPP1. Method of treating conditions associated with over-expression of ENPP1 gene with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.
    Type: Application
    Filed: November 1, 2021
    Publication date: May 5, 2022
    Inventors: Brahmam Pujala, Amantullah Ansari, Shreya Sapra, Pradeep S. Jadhavar, Dhananjay Pendharkar, Sreekanth A. Ramachandran, Uzma Saeed, Abhinandan Danodia, Farha Khan, Sagar Patni, Sanjeev Soni, Ashu Gupta, Sarvajit Chakravarty, Balaji Dashrath Sathe
  • HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
    Publication number: 20220119367
    Abstract: Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: January 17, 2020
    Publication date: April 21, 2022
    Inventors: Son Minh PHAM, Jayakanth KANKANALA, Pradeep S. JADHAVAR, Baban Mohan MULIK, Farha KHAN, Sreekanth A. RAMACHANDRAN
  • Heterocyclic compounds as adenosine antagonists
    Patent number: 11306071
    Abstract: 5,6-disubstituted 2-aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: April 19, 2022
    Assignee: Nuvation Bio Inc.
    Inventors: Son Minh Pham, Jayakanth Kankanala, Pradeep S. Jadhavar, Baban Mohan Mulik, Farha Khan, Sreekanth A. Ramachandran
  • 1,8-naphthyridinone compounds and uses thereof
    Patent number: 11254670
    Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: February 22, 2022
    Assignee: NUVATION BIO INC.
    Inventors: Son Minh Pham, Jayakanth Kankanala, Pradeep S. Jadhavar, Baban Mohan Mulik, Farha Khan, Sreekanth A. Ramachandran
  • HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
    Publication number: 20210292285
    Abstract: Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: February 12, 2021
    Publication date: September 23, 2021
    Inventors: Son Minh PHAM, Jiyun CHEN, Amantullah ANSARI, Pradeep S. JADHAVAR, Varshavekumar S. PATIL, Farha KHAN, Sreekanth A. RAMACHANDRAN, Anil Kumar AGARWAL, Sarvajit CHAKRAVARTY
  • Heterocyclic compounds as adenosine antagonists
    Patent number: 11028058
    Abstract: Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: June 8, 2021
    Assignee: NUVATION BIO INC.
    Inventors: Son Minh Pham, Jiyun Chen, Amantullah Ansari, Pradeep S. Jadhavar, Varshavekumar S. Patil, Farha Khan, Sreekanth A. Ramachandran, Anil Kumar Agarwal, Sarvajit Chakravarty
  • 1,8-naphthyridinone compounds and uses thereof
    Patent number: 10793561
    Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: October 6, 2020
    Assignee: NUVATION BIO INC.
    Inventors: Son Minh Pham, Jiyun Chen, Amantullah Ansari, Pradeep S. Jadhavar, Varshavekumar S. Patil, Farha Khan, Sreekanth A. Ramachandran, Anil Kumar Agarwal, Sarvajit Chakravarty
  • HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
    Publication number: 20200231570
    Abstract: Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: January 17, 2020
    Publication date: July 23, 2020
    Inventors: Son Minh PHAM, Jayakanth KANKANALA, Pradeep S. JADHAVAR, Baban Mohan MULIK, Farha KHAN, Sreekanth A. RAMACHANDRAN
  • 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF
    Publication number: 20200231589
    Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: January 17, 2020
    Publication date: July 23, 2020
    Inventors: Son Minh PHAM, Jayakanth KANKANALA, Pradeep S. JADHAVAR, Baban Mohan MULIK, Farha KHAN, Sreekanth A. RAMACHANDRAN
  • 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF
    Publication number: 20190023702
    Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: July 18, 2018
    Publication date: January 24, 2019
    Inventors: Son Minh PHAM, Jiyun CHEN, Amantullah ANSARI, Pradeep S. JADHAVAR, Varshavekumar S. PATIL, Farha KHAN, Sreekanth A. RAMACHANDRAN, Anil Kumar AGARWAL, Sarvajit CHAKRAVARTY
  • HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS
    Publication number: 20190023666
    Abstract: Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
    Type: Application
    Filed: July 18, 2018
    Publication date: January 24, 2019
    Inventors: Son Minh PHAM, Jiyun CHEN, Amantullah ANSARI, Pradeep S. JADHAVAR, Varshavekumar S. PATIL, Farha KHAN, Sreekanth A. RAMACHANDRAN, Anil Kumar AGARWAL, Sarvajit CHAKRAVARTY