Patents by Inventor Farhana BARMARE

Farhana BARMARE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF
    Publication number: 20220227808
    Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.
    Type: Application
    Filed: December 22, 2021
    Publication date: July 21, 2022
    Inventors: Ippei USUI, Bryan Junn LEE, Steven Bruce COHEN, Venkat Rami Reddy MACHERLA, Jacob Neal BEVERAGE, Chung-Mao PAN, Farhana BARMARE, Eduardo ESQUENAZI
  • COMPOUNDS FOR USE IN ANTI-CANCER IMMUNOTHERAPY
    Publication number: 20220226281
    Abstract: The present disclosure relates to the reversal of T cell exhaustion using aplysiatoxin analogs or PKC theta agonist compounds for anti-cancer immunotherapy. The treatment with aplysiatoxin analogs or PKC theta agonist compounds improve the anti-tumour activity of a T cell, inducing a NFAT-dependent T cell activation, increasing the pool of immune-checkpoint inhibitor responsive T cells, increasing lymphocyte infiltration and increasing the population of activated CD4+ and/or CD8+ cells. The methods of the present disclosure provide treatment of tumors and infections.
    Type: Application
    Filed: May 28, 2020
    Publication date: July 21, 2022
    Inventors: Steven Bruce Cohen, Dan Lu, Farhana Barmare, Ippei Usui, Venkata Rami Reddy Macherla, Elizabeth Paige Stout, Jacob Neal Beverage, Eduardo Esquenazi, Peter A. Jordan, Phil S. Baran, John R. Teijaro
  • Cyclic peptide analogs and conjugates thereof
    Patent number: 11254705
    Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: February 22, 2022
    Assignee: SIRENAS LLC
    Inventors: Ippei Usui, Bryan Junn Lee, Steven Bruce Cohen, Venkat Rami Reddy Macherla, Jacob Neal Beverage, Chung-Mao Pan, Farhana Barmare, Eduardo Esquenazi
  • CYCLIC PEPTIDE ANALOGS AND CONJUGATES THEREOF
    Publication number: 20190211060
    Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.
    Type: Application
    Filed: August 31, 2017
    Publication date: July 11, 2019
    Applicant: SIRENAS LLC
    Inventors: Ippei USUI, Bryan Junn LEE, Steven Bruce COHEN, Venkat Rami Reddy MACHERLA, Jacob Neal BEVERAGE, Chung-Mao PAN, Farhana BARMARE, Eduardo ESQUENAZI