Patents by Inventor Farshad Guirakhoo

Farshad Guirakhoo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Generating an Immune Response to a Tumor Associated Antigen
    Publication number: 20190290745
    Abstract: The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
    Type: Application
    Filed: January 9, 2017
    Publication date: September 26, 2019
    Inventors: Harriet Robinson, Arban Domi, Michael Hellerstein, Farshad Guirakhoo, Nathanael Paul McCurley
  • CMV VACCINES
    Publication number: 20190247493
    Abstract: Provided herein are genetically modified arenaviral vectors suitable as vaccines for prevention and treatment of cytomegalovirus infections and reactivation. Also provided herein are pharmaceutical compositions and methods for the treatment of cytomegalovirus infections and reactivation. Specifically, provided herein are pharmaceutical compositions, vaccines, and methods of treating cytomegalovirus infections and reactivation.
    Type: Application
    Filed: September 20, 2018
    Publication date: August 15, 2019
    Inventors: Klaus Orlinger, Karen Lingnau, Thomas Monath, Farshad Guirakhoo, Gerhard Fuhrmann, Katherine Cohen, Vera Baumgartl-Strasser, Andreas Aspöck, Manuela Kainer, Bernhard Brim, Bettina Kiefmann, Elizabeth Watson, Mario Aistleithner, Katharina Bayer, Elsa Mühlbacher
  • FLAVIVIRUS VACCINES
    Publication number: 20190192649
    Abstract: The invention provides flavivirus vaccines and methods of making and using these vaccines.
    Type: Application
    Filed: November 26, 2018
    Publication date: June 27, 2019
    Inventors: Thomas P. MONATH, Farshad GUIRAKHOO, Juan ARROYO, Konstantin V. PUGACHEV
  • Compositions and Methods for Generating an Immune Response to Hepatitis B Virus
    Publication number: 20190184009
    Abstract: The compositions and methods are described for generating an immune response to a hepatitis B virus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a hepatitis B virus, in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by hepatitis B virus.
    Type: Application
    Filed: May 30, 2017
    Publication date: June 20, 2019
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael P. McCurley, Rahul Basu, Ming Luo
  • Compositions and Methods for Generating an Immune Response to a Flavivirus
    Publication number: 20190030157
    Abstract: The compositions and methods are described for generating an immune response to a flavivirus such as Zika virus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Flavivirus (such as a member of species Zika virus), in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by Flavivirus.
    Type: Application
    Filed: February 1, 2017
    Publication date: January 31, 2019
    Inventors: Farshad Guirakhoo, Arban Domi, Nathanael Paul McCurley
  • Flavivirus vaccines
    Patent number: 10172929
    Abstract: The invention provides flavivirus vaccines and methods of making and using these vaccines.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: January 8, 2019
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Thomas P. Monath, Farshad Guirakhoo, Juan Arroyo, Konstantin V. Pugachev
  • CMV vaccines
    Patent number: 10111945
    Abstract: Provided herein are genetically modified arenaviral vectors suitable as vaccines for prevention and treatment of cytomegalovirus infections and reactivation. Also provided herein are pharmaceutical compositions and methods for the treatment of cytomegalovirus infections and reactivation. Specifically, provided herein are pharmaceutical compositions, vaccines, and methods of treating cytomegalovirus infections and reactivation.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: October 30, 2018
    Assignee: Hookipa Biotech GmbH
    Inventors: Klaus Orlinger, Karen Lingnau, Thomas Monath, Farshad Guirakhoo, Gerhard Fuhrmann, Katherine Cohen, Vera Baumgartl-Strasser, Andreas Aspöck, Manuela Kainer, Bernhard Brim, Bettina Kiefmann, Elizabeth Watson, Mario Aistleithner, Katharina Bayer, Elsa Mühlbacher
  • CMV VACCINES
    Publication number: 20160296619
    Abstract: Provided herein are genetically modified arenaviral vectors suitable as vaccines for prevention and treatment of cytomegalovirus infections and reactivation. Also provided herein are pharmaceutical compositions and methods for the treatment of cytomegalovirus infections and reactivation. Specifically, provided herein are pharmaceutical compositions, vaccines, and methods of treating cytomegalovirus infections and reactivation.
    Type: Application
    Filed: December 3, 2014
    Publication date: October 13, 2016
    Inventors: Klaus Orlinger, Karen Lingnau, Thomas Monath, Farshad Guirakhoo, Gerhard Fuhrmann, Katherine Cohen, Vera Baumgartl-Strasser, Andreas Aspöck, Manuelaö Kainer, Bernhard Brim, Bettina Kiefmann, Elizabeth Watson, Mario Aistleithner, Katharina Bayer, Elsa Mülbacher
  • Recombinant bicistronic flavivirus vectors
    Patent number: 9228203
    Abstract: This invention relates to bicistronic flavivirus vectors, methods of using such vectors in the prevention and treatment of disease, and methods of making such vectors.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: January 5, 2016
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Simon Delagrave, Nathan Brown, Harold Kleanthous, Farshad Guirakhoo, Alexander A. Rumyantsev
  • FLAVIVIRUS VACCINES
    Publication number: 20150024004
    Abstract: The invention provides flavivirus vaccines and methods of making and using these vaccines.
    Type: Application
    Filed: October 6, 2014
    Publication date: January 22, 2015
    Inventors: Thomas P. MONATH, Farshad GUIRAKHOO, Juan ARROYO, Konstantin V. PUGACHEV
  • Recombinant vaccines
    Patent number: 8871222
    Abstract: The invention provides recombinant flavivirus vaccines that can be used in the prevention and treatment of flavivirus infection. The vaccines of the invention contain recombinant flaviviruses including attenuating mutations.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: October 28, 2014
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Konstantin V. Pugachev, Farshad Guirakhoo, Thomas P. Monath
  • Flavivirus vaccines
    Patent number: 8852914
    Abstract: The invention provides flavivirus vaccines and methods of making and using these vaccines.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: October 7, 2014
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Thomas P. Monath, Farshad Guirakhoo, Juan Arroyo, Konstantin V. Pugachev
  • Vaccines against japanese encephalitis virus and west nile virus
    Patent number: 8691550
    Abstract: The invention provides attenuated Flavivirus vaccines, such as vaccines against Japanese encephalitis virus and West Nile virus, as well as methods of making and using these vaccines.
    Type: Grant
    Filed: October 3, 2011
    Date of Patent: April 8, 2014
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Farshad Guirakhoo, J. Jian Liu, John A. Catalan, Thomas P. Monath, Konstantin V. Pugachev
  • Flavivirus vaccine vector against influenza virus
    Patent number: 8591916
    Abstract: This invention relates to chimeric flavivirus vectors that can be used, for example, in the prevention and treatment of influenza virus infection, compositions including such viral vectors, and methods employing the vectors.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: November 26, 2013
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Simon Delagrave, Farshad Guirakhoo, Caroline Maier, Alexander A. Rumyantsev
  • RECOMBINANT BICISTRONIC FLAVIVIRUS VECTORS
    Publication number: 20130295134
    Abstract: This invention relates to bicistronic flavivirus vectors, methods of using such vectors in the prevention and treatment of disease, and methods of making such vectors.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 7, 2013
    Inventors: Simon DELAGRAVE, Nathan Brown, Harold Kleanthous, Farshad Guirakhoo, Alexander A. Rumyantsev
  • Recombinant bicistronic vectors
    Patent number: 8486417
    Abstract: This invention relates to bicistronic flavivirus vectors, methods of using such vectors in the prevention and treatment of disease, and methods of making such vectors.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: July 16, 2013
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Simon Delagrave, Nathan Brown, Harold Kleanthous, Farshad Guirakhoo, Alexander Rumyantsev
  • Tetravalent Dengue Vaccines
    Publication number: 20130095136
    Abstract: The invention provides tetravalent Dengue vaccines, and methods of using these vaccines to prevent or to treat Dengue infection.
    Type: Application
    Filed: May 18, 2012
    Publication date: April 18, 2013
    Applicant: Sanofi Pasteur Biologics, LLC
    Inventor: Farshad Guirakhoo
  • Recombinant Flavivirus Vaccines
    Publication number: 20120288520
    Abstract: The invention provides recombinant flavivirus vaccines that can be used in the prevention and treatment of flavivirus infection. The vaccines of the invention contain recombinant flaviviruses including attenuating mutations.
    Type: Application
    Filed: February 27, 2012
    Publication date: November 15, 2012
    Applicant: Sanofi Pasteur Biologics, LLC
    Inventors: Konstantin V. Pugachev, Farshad Guirakhoo, Thomas P. Monath
  • Vaccines Against Japanese Encephalitis Virus and West Nile Virus
    Publication number: 20120201852
    Abstract: The invention provides attenuated Flavivirus vaccines, such as vaccines against Japanese encephalitis virus and West Nile virus, as well as methods of making and using these vaccines.
    Type: Application
    Filed: October 3, 2011
    Publication date: August 9, 2012
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Farshad Guirakhoo, J. Jian Liu, John A. Catalan, Thomas P. Monath, Konstantin V. Pugachev
  • Recombinant flavivirus vaccines
    Patent number: 8124398
    Abstract: The invention provides recombinant flavivirus vaccines that can be used in the prevention and treatment of flavivirus infection. The vaccines of the invention contain recombinant flaviviruses including attenuating mutations.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: February 28, 2012
    Assignee: Sanofi Pasteur Biologics Co.
    Inventors: Konstantin V. Pugachev, Farshad Guirakhoo, Thomas P. Monath