Abstract: A multimode biological sample inspection apparatus and method is provided. The apparatus includes an illumination hardware arrangement comprising transmission and sensing hardware configured to inspect a biological sample using at least two modes from a group comprising a fluorescence imaging mode, a reflectance imaging mode, a scattering imaging mode, and a Raman imaging mode, and processing hardware configured to operate the illumination hardware arrangement according to a protocol comprising inspection settings of the at least two modes. The processing hardware receives scan results from the illumination hardware arrangement and identifies attributes of the biological sample by constructing a multidimensional dataset comprising at least one spatial dimension and at least one spectral dimension from the scan results and analyzing the multidimensional dataset. The processing hardware is configured to employ the attributes of at least one biological sample and alter the protocol.

Abstract: A system for assessing biological tissue is disclosed. The system contains an illumination hardware arrangement comprising transmission and sensing hardware, the illumination hardware arrangement configured to inspect a biological tissue using at least two modes from a group containing: a three dimensional stereo imaging mode; a fluorescence imaging mode; a reflectance imaging mode; and a thermal imaging mode; and processing hardware configured to operate the illumination hardware arrangement according to a protocol comprising inspection settings of the at least two modes, wherein the processing hardware receives scan results for the at least two modes from the illumination hardware arrangement and identifies attributes of the biological tissue by constructing a three dimensional dataset from the scan results for the at least two modes and analyzing the three dimensional dataset.

Abstract: A method is disclosed. The method inspects a product using a first fluorescence imaging mode, a second fluorescence imaging mode, and a reflectance imaging mode, generates one or more final predictions based on the first fluorescence imaging mode, the second fluorescence imaging mode, and the reflectance imaging mode, collects data from one or more sensors, validates data collected from the one or more sensors, prepares a transaction based on the validated data and the one or more final predictions, broadcasts the transaction to a blockchain network, validates the transaction, and adds new block to the blockchain network based on validated transaction.

Abstract: A surface of the tissue is illuminated with light having a known wavelength spectrum capable of materially penetrating the tissue. The light remitted from the tissue in response to the illumination is separated into at least two distinguishable polarization components. The intensity of the illumination light remitted from the tissue is measured over a hyperspectral range of wavelengths for the at least two distinguishable polarization components. Based on the preceding measurements and a degree of linear polarization of the remitted light, data representative of the three-dimensional location and one or more characteristics of an abnormal portion of the tissue are produced. Further, the masking effect of melanin may be eliminated to obtain accurate estimations of an anomaly.

Abstract: The contamination sanitation inspection system (CSIS) allows a user to capture an image of a large scene (such as a food processing line, a food service facility, a food products storage area, or a plant production area/facility) and identify contamination within the scene and preferably represent the contamination on a spatially accurate map (or floorplan) so that contamination within the inspection map area is clearly identified and recorded for subsequent treatment. In an alternative embodiment, the CSIS also includes a decontamination system to sanitize any identified contamination.

Abstract: A system for assessing biological tissue is disclosed.

Abstract: A multimode biological sample inspection apparatus and method is provided. The apparatus includes an illumination hardware arrangement comprising transmission and sensing hardware configured to inspect a biological sample using at least two modes from a group comprising a fluorescence imaging mode, a reflectance imaging mode, a scattering imaging mode, and a Raman imaging mode, and processing hardware configured to operate the illumination hardware arrangement according to a protocol comprising inspection settings of the at least two modes. The processing hardware receives scan results from the illumination hardware arrangement and identifies attributes of the biological sample by constructing a multidimensional dataset comprising at least one spatial dimension and at least one spectral dimension from the scan results and analyzing the multidimensional dataset. The processing hardware is configured to employ the attributes of at least one biological sample and alter the protocol.

Abstract: A multimode biological sample inspection apparatus and method is provided. The apparatus includes illumination hardware arrangement including transmission and sensing hardware, the illumination hardware arrangement configured to inspect a biological sample using at least two modes from a fluorescence imaging mode, a reflectance imaging mode, a scattering imaging mode, and a Raman imaging mode, and processing hardware configured to operate the illumination hardware arrangement according to a protocol including inspection settings of the at least two modes. The processing hardware receives scan results from the illumination hardware arrangement and identifies attributes of the biological sample. The processing hardware is configured to employ the attributes of at least one biological sample to alter the protocol.

Abstract: A device is disclosed. The device contains a first light source configured to excite fluorescence emission of a first contaminant on a surface, and a first optical sensor configured to capture one or more images of the fluorescence emission of the first contaminant.

Abstract: A method and system are provided for characterizing a portion of biological tissue. This invention comprises a smartphone and tablet deployable mobile medical application that uses device sensors, internet connectivity and cloud-based image processing to document and analyze physiological characteristics of hand arthritis. The application facilitates image capture and performs image processing that identifies hand fiduciary features and measures hand anatomical features to report and quantify the progress of arthritic disease.

Abstract: A method and system are provided for characterizing a portion of biological tissue. This invention comprises a smartphone and tablet deployable mobile medical application that uses device sensors, internet connectivity and cloud-based image processing to document and analyze physiological characteristics of hand arthritis. The application facilitates image capture and performs image processing that identifies hand fiduciary features and measures hand anatomical features to report and quantify the progress of arthritic disease.

Abstract: A multimode biological sample inspection apparatus and method is provided. The apparatus includes illumination hardware arrangement including transmission and sensing hardware, the illumination hardware arrangement configured to inspect a biological sample using at least two modes from a fluorescence imaging mode, a reflectance imaging mode, a scattering imaging mode, and a Raman imaging mode, and processing hardware configured to operate the illumination hardware arrangement according to a protocol including inspection settings of the at least two modes. The processing hardware receives scan results from the illumination hardware arrangement and identifies attributes of the biological sample. The processing hardware is configured to employ the attributes of at least one biological sample to alter the protocol.

Abstract: A method and system are provided for characterizing a portion of biological tissue. This invention comprises a smartphone and tablet deployable mobile medical application that uses device sensors, internet connectivity and cloud-based image processing to document and analyze physiological characteristics of hand arthritis. The application facilitates image capture and performs image processing that identifies hand fiduciary features and measures hand anatomical features to report and quantify the progress of arthritic disease.

Abstract: Provided herein are methods for classifying or characterizing a biological sample in vivo or ex vivo in real-time using time-resolved spectroscopy and/or electrical stimulation. A biological sample may produce a responsive fluorescence signal when irradiated by a light excitation signal or pulse at a predetermined wavelength. The responsive fluorescence signal may be recorded. The intensity of the excitation wavelength may be recorded and used to normalize the recorded responsive fluorescence signal. The biological sample may produce a responsive electrical signal in response to electrical stimulation. Raw fluorescence decay data may be generated from the responsive fluorescence signal and pre-processed. The pre-processed raw fluorescence decay data may be de-convolved to remove an instrument response function therefrom and generate true fluorescence decay data.

Abstract: A method and system are provided for characterizing a portion of biological tissue. A surface of the tissue is illuminated with light having a known wavelength spectrum capable of materially penetrating the tissue. The intensity of the illumination light remitted from the tissue in response to the illumination over a known measurement window is measured over a hyperspectral range of wavelengths for at least two distinguishable polarization components. Based on a model of the response of the tissue and the preceding measurements, data representative of the location and one or more characteristics of an abnormal portion of the tissue are produced. A method is provided to eliminate the masking effect of melanin to obtain accurate estimations of an anomaly.

Abstract: A disposable tubular end cap for a dermoscope for examining the skin of an animal. The end cap has one end for receiving light from and transmitting light to the dermoscope, a removable calibration target disposed at the other end having optical characteristics similar to a standard skin type, and an identifier disposed on the end cap. The identifier uniquely identifies the end cap and associates it with both data regarding light emitted from the skin of an animal and calibration data derived from the calibration target. Animal tissue may be examined to identify lesions using a plurality of wavelengths and a plurality of polarizations.

Abstract: An apparatus including a three dimensional sub-wavelength structure for electromagnetic applications including a surface layer formed of a metal or semiconductor film, one or more additional layers stacked to the surface layer, one or more sub-wavelength apertures in the surface layer, and one or more cavities nearby the one or more sub-wavelength apertures. The size of each aperture is smaller than the wavelength of the electromagnetic field incident upon the three dimensional sub-wavelength structure. The one or more cavities provide accessibility for a dielectric material within and below each aperture. Each cavity may also contain at least one metal or semiconductor sub-wavelength particle. A method of fabricating a three dimensional sub-wavelength structure is also provided.

Abstract: An angular filter is provided, including a straight tunnel within a material, the tunnel having a roughened surface. When scattered light enters the tunnel, and strikes the roughened surface at a shallow angle, the scatter light is further scattered within the tunnel, striking the surface of the tunnel a multiplicity of times. Each such strike partially absorbs the light ray, such that the intensity of the scattered light exiting the tunnel is minimized.