Abstract: A hyaluronic acid hydrogel formulation including phytoestrogen for the treatment of vaginal atrophy and vaginal rejuvenation and production method thereof is provided. The phytoestrogens included in the hyaluronic acid hydrogel formulation are herbal substances that can produce estrogenic effects and have the same structure and functions as estradiol. In this way, risks such as heart attack, stroke, and blood clotting seen in alternative treatment methods including hormone are not encountered.

Abstract: A hydrogel formulation is developed to be used in ophthalmological applications and as a vitreous substitute. More specifically, a hybrid hydrogel formulation including a cross-linked hyaluronic acid and collagen complex is provided. The hybrid hydrogel formulation can further include a sulfated glycosaminoglycan (sGAG) or ascorbic acid and/or an ascorbic acid derivative.

Abstract: An ophthalmic formulation for the treatment of presbyopia, dry eye disease and computer vision syndrome, and a method for preparing the same is provided.

Abstract: An ophthalmic formulations developed for the treatment and prevention of cataract and a method for preparation thereof are provided. The objective of the present invention is to develop an ophthalmic topical formulation which the patients can use themselves non-invasively in order to prevent development of cataract in risk groups or to treat existing cataracts.

Abstract: Spin-assisted layer-by-layer polymer coatings are used as the inner surface coating material for intraocular lens cartridges and facilitate the implantation of intraocular lenses.

Abstract: Crosslinked polymer coatings which provide the lubrication of the inner surface of a cartridge used as an intermediary for the implantation of intraocular lenses (IOL) in order to replace the natural lens with an artificial lens after removal of the natural lens that has lost its transparency in cataract surgery, in order to facilitate the delivery of the intraocular lens are provided. The objective of the invention is to develop a coating which will enable the intraocular lens (IOL) to be easily implanted through the cartridge without damaging it, remains stable during its long shelf life, and is flexible and lubricious.

Abstract: An injectable viscoelastic hydrogel formulation comprising photocrosslinked hyaluronic acid in order to relieve pain caused by osteoarthritis (OA), to support synovial fluid which has decreased activity, and to treat osteochondral lesions is provided. In the production of hyaluronic acid (HA) hydrogels, the crosslinking process is carried out via biocompatible camphorquinone instead of synthetic crosslinkers having toxic effects. Therefore, long process times in the purification process of synthetic crosslinkers are significantly reduced with the present invention.