Patents by Inventor Fashu Ma

Fashu Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of cyclosporin derivatives
    Patent number: 12673976
    Abstract: The invention provides a process for the preparation of cyclosporin derivatives.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: July 7, 2026
    Assignee: Farsight Medical Technology (Shanghai) Co., Ltd.
    Inventors: Fashu Ma, Ching-Pong Mak, Daofei Li, Xiao Yu
  • Cyclophilin inhibitors and uses thereof
    Patent number: 12522634
    Abstract: Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, in particular diseases or conditions associated with cellular injury or cell death, such as organ injury or organ failure, which can be caused by a number of different reasons, such as ischemia or ischemia reperfusion injury, toxins, infection or mechanical trauma.
    Type: Grant
    Filed: June 26, 2024
    Date of Patent: January 13, 2026
    Assignee: Farsight Medical Technology (Shanghai) Co., Ltd.
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • Prevention and treatment of organ injuries
    Patent number: 12465629
    Abstract: The invention provides for Compound I or a pharmaceutically acceptable salt thereof (I) for use in the prevention and/or treatment of an organ injury, or a condition associated with an organ injury, in a subject diagnosed with, or suffering from an infection.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: November 11, 2025
    Assignee: Farsight Medical Technology (Shanghai) Co., Ltd.
    Inventors: Ching-Pong Mak, Fashu Ma, Dong Xiao, Michael Peel, Hans Fliri
  • TREATMENT AND PREVENTION OF NEPHROTOXIN-INDUCED KIDNEY INJURIES
    Publication number: 20250288639
    Abstract: The invention provides for Compound I or a pharmaceutically acceptable salt thereof for use in the prevention and/or treatment of a kidney condition or disease in a subject exposed to a nephrotoxin capable of inducing said kidney condition or disease.
    Type: Application
    Filed: June 3, 2025
    Publication date: September 18, 2025
    Inventors: Michael Robert Peel, Fashu Ma, Hans Georg Fliri, Ching Pong Mak, Dong Xiao
  • Treatment and prevention of nephrotoxin-induced kidney injuries
    Patent number: 12350310
    Abstract: Provided herein is Compound I or a pharmaceutically acceptable salt thereof for use in the prevention and/or treatment of a kidney condition or disease in a subject exposed to a nephrotoxin capable of inducing said kidney condition or disease.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: July 8, 2025
    Assignee: Farsight Medical Technology (Shanghai) Co., Ltd.
    Inventors: Michael Robert Peel, Fashu Ma, Hans Georg Fliri, Ching Pong Mak, Dong Xiao
  • CYCLOPHILIN INHIBITORS AND USES THEREOF
    Publication number: 20240352074
    Abstract: Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, in particular diseases or conditions associated with cellular injury or cell death, such as organ injury or organ failure, which can be caused by a number of different reasons, such as ischemia or ischemia reperfusion injury, toxins, infection or mechanical trauma.
    Type: Application
    Filed: June 26, 2024
    Publication date: October 24, 2024
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • Cyclophilin inhibitors and uses thereof
    Patent number: 12060440
    Abstract: Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, such as organ injury or organ failure.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: August 13, 2024
    Assignee: FARSIGHT MEDICAL TECHNOLOGY (SHANGHAI) CO., LTD.
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • CYCLOPHILIN INHIBITORS AND USES THEREOF
    Publication number: 20230203099
    Abstract: Provided are compounds as defined by Formula 1 and uses thereof for the prevention or treatment of disease or conditions such as organ injury or organ failure.
    Type: Application
    Filed: March 25, 2021
    Publication date: June 29, 2023
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
  • PREVENTION AND TREATMENT OF ORGAN INJURIES
    Publication number: 20230181680
    Abstract: The invention provides for Compound I or a pharmaceutically acceptable salt thereof (I) for use in the prevention and/or treatment of an organ injury, or a condition associated with an organ injury, in a subject diagnosed with, or suffering from an infection.
    Type: Application
    Filed: April 15, 2021
    Publication date: June 15, 2023
    Inventors: Ching-Pong Mak, Fashu Ma, Dong Xiao, Michael Peel, Hans Fliri
  • TREATMENT AND PREVENTION OF NEPHROTOXIN-INDUCED KIDNEY INJURIES
    Publication number: 20230173017
    Abstract: Provided herein is Compound I or a pharmaceutically acceptable salt thereof for use in the prevention and/or treatment of a kidney condition or disease in a subject exposed to a nephrotoxin capable of inducing said kidney condition or disease.
    Type: Application
    Filed: October 12, 2020
    Publication date: June 8, 2023
    Inventors: Michael Robert Peel, Fashu Ma, Hans Georg Fliri, Ching Pong Mak, Dong Xiao
  • PREPARATION OF CYCLOSPORIN DERIVATIVES
    Publication number: 20230174583
    Abstract: The invention provides a process for the preparation of cyclosporin derivatives.
    Type: Application
    Filed: March 25, 2021
    Publication date: June 8, 2023
    Inventors: Fashu Ma, Ching-Pong Mak, Daofei Li, Xiao Yu
  • CYCLOPHILIN INHIBITORS AND USES THEREOF
    Publication number: 20230110497
    Abstract: Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, such as organ injury or organ failure.
    Type: Application
    Filed: September 16, 2022
    Publication date: April 13, 2023
    Inventors: Ching-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel