Patents by Inventor Fatma Ayhan

Fatma Ayhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MANIPULATION OF EIF3 TO MODULATE REPEAT ASSOCIATED NON-ATG (RAN) TRANSLATION
    Publication number: 20250375466
    Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.
    Type: Application
    Filed: June 20, 2025
    Publication date: December 11, 2025
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Laura Ranum, Fatma Ayhan, Tao Zu
  • Manipulation of eIF3 to modulate repeat associated non-ATG (RAN) translation
    Patent number: 12364707
    Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: July 22, 2025
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Laura Ranum, Fatma Ayhan, Tao Zu
  • MANIPULATION OF EIF3 TO MODULATE REPEAT ASSOCIATED NON-ATG (RAN) TRANSLATION
    Publication number: 20210236535
    Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.
    Type: Application
    Filed: January 27, 2021
    Publication date: August 5, 2021
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Laura Ranum, Fatma Ayhan, Tao Zu
  • Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation
    Patent number: 10940161
    Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: March 9, 2021
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Laura Ranum, Fatma Ayhan, Tao Zu
  • MANIPULATION OF EIF3 TO MODULATE REPEAT ASSOCIATED NON-ATG (RAN) TRANSLATION
    Publication number: 20200206255
    Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.
    Type: Application
    Filed: April 4, 2017
    Publication date: July 2, 2020
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Laura Ranum, Fatma Ayhan, Tao Zu
  • MANIPULATION OF EIF3 TO MODULATE REPEAT ASSOCIATED NON-ATG (RAN) TRANSLATION
    Publication number: 20190142858
    Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.
    Type: Application
    Filed: April 4, 2017
    Publication date: May 16, 2019
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Laura Ranum, Fatma Ayhan, Tao Zu