Patents by Inventor Fayna C. DIAZ-SAN SEGUNDO

Fayna C. DIAZ-SAN SEGUNDO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically engineered foot and mouth disease virus and related proteins, polynucleotides, compositions, methods and systems
    Patent number: 11813320
    Abstract: Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: November 14, 2023
    Assignees: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC, THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE, THE UNIVERSITY OF CONNECTICUT
    Inventors: Aida E. Rieder, Teresa B. De Los Santos, Luis L. Rodriguez, Devendra Rai, Fayna C. Diaz-San Segundo, Paul D. Hoeprich
  • Live attenuated strains of foot and mouth disease modified by deoptimization and uses thereof
    Patent number: 11793870
    Abstract: The present disclosure describes deoptimized foot and mouth viruses and their use for prophylactic and therapeutic treatment of mammalian subjects. The recombinant viruses provided herein include alterations in several genomic regions as well as Differentiating Infected from Vaccinated Animals (DIVA) markers.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: October 24, 2023
    Assignees: The United States of America, as represented by The Secretary of Agriculture, Codagenix Inc.
    Inventors: Teresa B. De Los Santos, Aida E. Rieder, Fayna C. Diaz-San Segundo, Anna Kloc, John R. Coleman, Steffen Mueller, Gisselle N. Medina
  • DEVELOPMENT OF MOSAIC VACCINES AGAINST FOOT AND MOUTH DISEASE VIRUS SEROTYPE O
    Publication number: 20230149528
    Abstract: Synthetic foot-and-mouth disease virus (FMDV) mosaic polypeptides, and nucleic acid molecules encoding the mosaic polypeptides, are described. When included as part of an FMDV genome, the mosaic polypeptides permit virus replication and assembly into FMDV particles. The mosaic polypeptide and nucleic acid compositions can be used to elicit immune responses that provide protection against a broad range of serotype O FMDV strains.
    Type: Application
    Filed: August 17, 2022
    Publication date: May 18, 2023
    Inventors: Aida E. Rieder, KATHERINE M. PFLAUM, FAYNA C. DIAZ SAN SEGUNDO, WILLIAM M. FISCHER, TATJANA SITT
  • LIVE ATTENUATED STRAINS OF FOOT AND MOUTH DISEASE MODIFIED BY DEOPTIMIZATION AND USES THEREOF
    Publication number: 20210401967
    Abstract: The present disclosure describes deoptimized foot and mouth viruses and their use for prophylactic and therapeutic treatment of mammalian subjects. The recombinant viruses provided herein include alterations in several genomic regions as well as Differentiating Infected from Vaccinated Animals (DIVA) markers.
    Type: Application
    Filed: May 26, 2021
    Publication date: December 30, 2021
    Inventors: TERESA B. DE LOS SANTOS, AIDA E. RIEDER, FAYNA C. DIAZ-SAN SEGUNDO, ANNA KLOC, JOHN R. COLEMAN, STEFFEN MUELLER, GISSELLE N. MEDINA
  • GENETICALLY ENGINEERED FOOT AND MOUTH DISEASE VIRUS AND RELATED PROTEINS, POLYNUCLEOTIDES, COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20210187095
    Abstract: Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.
    Type: Application
    Filed: February 16, 2021
    Publication date: June 24, 2021
    Inventors: Aida E. RIEDER, Teresa B. DE LOS SANTOS, Luis L. RODRIGUEZ, Devendra RAI, Fayna C. DIAZ-SAN SEGUNDO, Paul D. HOEPRICH
  • Genetically engineered Foot and Mouth Disease Virus and related proteins, polynucleotides, compositions, methods and systems
    Patent number: 10953085
    Abstract: Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: March 23, 2021
    Assignees: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC, THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE, THE UNIVERSITY OF CONNECTICUT
    Inventors: Aida E. Rieder, Teresa B. De Los Santos, Luis L. Rodriguez, Devendra Rai, Fayna C. Diaz-San Segundo, Paul D. Hoeprich
  • GENETICALLY ENGINEERED FOOT AND MOUTH DISEASE VIRUS AND RELATED PROTEINS, POLYNUCLEOTIDES, COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20180326038
    Abstract: Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.
    Type: Application
    Filed: May 9, 2017
    Publication date: November 15, 2018
    Inventors: Aida E. RIEDER, Teresa B. DE LOS SANTOS, Luis L. RODRIGUEZ, Devendra RAI, Fayna C. DIAZ-SAN SEGUNDO, Paul D. HOEPRICH