Patents by Inventor Faysal Kalmoua

Faysal Kalmoua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical tablets of crystalline type II aripiprazole
    Patent number: 8529949
    Abstract: Crystalline aripiprazole Type II can be formulated into pharmaceutical tablets having reduced dissolution profile variability upon storage.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: September 10, 2013
    Assignee: Synthon BV
    Inventors: Gerrit J. B. Ettema, Raymond J. H. Westheim, Faysal Kalmoua, Korinde Annemarie Jansen, Farid Abedin Dorkoosh
  • Process of making crystalline type II aripiprazole
    Patent number: 8093387
    Abstract: Crystalline aripiprazole Type II can be formed without solid state heat treatment. Instead a liquid is used such as in crystallizing from a solvent, especially 2-propanol, dimethyl sulfoxide, or a combination thereof with ethyl acetate, or in a solvent mediated solid-solid transformation, typically in ethyl acetate.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: January 10, 2012
    Assignee: Synthon BV
    Inventors: Gerrit J. B. Ettema, Raymond J. H. Westheim, Faysal Kalmoua
  • Crystalline aripiprazole solvates
    Patent number: 7902198
    Abstract: Alcoholates of aripiprazole are useful as pharmaceuticals and/or as intermediates in making aripiprazole Form A or Form B.
    Type: Grant
    Filed: November 18, 2005
    Date of Patent: March 8, 2011
    Assignee: Synthon BV
    Inventors: Gerrit Jan Ettema, Raymond Westheim, Faysal Kalmoua
  • Process of making crystalline type II aripiprazole
    Publication number: 20100196710
    Abstract: Crystalline aripiprazole Type II can be formed without solid state heat treatment. Instead a liquid is used such as in crystallizing from a solvent, especially 2-propanol, dimethyl sulfoxide, or a combination thereof with ethyl acetate, or in a solvent mediated solid-solid transformation, typically in ethyl acetate.
    Type: Application
    Filed: December 24, 2009
    Publication date: August 5, 2010
    Inventors: Gerrit J. B. Ettema, Raymond J. H. Westheim, Faysal Kalmoua
  • Process of making crystalline Type II aripiprazole
    Patent number: 7655798
    Abstract: Crystalline aripiprazole Type II can be formed without solid state heat treatment. Instead a liquid is used such as in crystallizing from a solvent, especially 2-propanol, dimethyl sulfoxide, or a combination thereof with ethyl acetate, or in a solvent mediated solid-solid transformation, typically in ethyl acetate.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: February 2, 2010
    Assignee: Synthon BV
    Inventors: Gerrit J. B. Ettema, Raymond J. H. Westheim, Faysal Kalmoua
  • Process of making crystalline aripiprazole
    Patent number: 7642353
    Abstract: Crystalline aripiprazole Form B can be formed by crystallizing from a solvent selected from 1-propanol, 2-propanol, 1-butanol, ethyl acetate, acetonitrile or a combination thereof.
    Type: Grant
    Filed: November 18, 2005
    Date of Patent: January 5, 2010
    Assignee: Synthon BV
    Inventors: Gerrit Jan Ettema, Raymond Westheim, Faysal Kalmoua
  • Pharmaceutical tablets of crystalline Type II aripiprazole
    Publication number: 20060257471
    Abstract: Crystalline aripiprazole Type II can be formulated into pharmaceutical tablets having reduced dissolution profile variability upon storage.
    Type: Application
    Filed: March 17, 2006
    Publication date: November 16, 2006
    Inventors: Gerrit Ettema, Raymond Westheim, Faysal Kalmoua, Korinde Jansen, Farid Dorkoosh
  • Process of making crystalline Type II aripiprazole
    Publication number: 20060258673
    Abstract: Crystalline aripiprazole Type II can be formed without solid state heat treatment. Instead a liquid is used such as in crystallizing from a solvent, especially 2-propanol, dimethyl sulfoxide, or a combination thereof with ethyl acetate, or in a solvent mediated solid-solid transformation, typically in ethyl acetate.
    Type: Application
    Filed: March 17, 2006
    Publication date: November 16, 2006
    Inventors: Gerrit Ettema, Raymond Westheim, Faysal Kalmoua
  • Process of making crystalline aripiprazole
    Publication number: 20060142579
    Abstract: Crystalline aripiprazole Form B can be formed by crystallizing from a solvent selected from 1-propanol, 2-propanol, 1-butanol, ethyl acetate, acetonitrile or a combination thereof.
    Type: Application
    Filed: November 18, 2005
    Publication date: June 29, 2006
    Inventors: Gerrit Ettema, Raymond Westheim, Faysal Kalmoua
  • Crystalline aripiprazole solvates
    Publication number: 20060142299
    Abstract: Alcoholates of aripiprazole are useful as pharmaceuticals and/or as intermediates in making aripiprazole Form A or Form B.
    Type: Application
    Filed: November 18, 2005
    Publication date: June 29, 2006
    Inventors: Gerrit Ettema, Raymond Westheim, Faysal Kalmoua
  • Liquid paroxetine compositions
    Publication number: 20060063737
    Abstract: A liquid paroxetine composition containing at least 5 mg/ml of paroxetine or a pharmaceutically acceptable salt thereof, a non-carbohydrate sweetener, and a solvent containing 60-100% of ethanol, polyol or mixtures and 0-40% of water, provides for good stability and taste.
    Type: Application
    Filed: August 17, 2005
    Publication date: March 23, 2006
    Inventors: Lisa Holmdahl, Faysal Kalmoua, Frans Dalen
  • Process for preparing bisindenylalkanes
    Patent number: 6414206
    Abstract: The present invention relates to a process for preparing bisindenylalkanes of formula I: wherein R1, R2, R3, and R4 independently represent H or a C1-C6 hydrocarbon group or R1 and R2 or R1 and R3 or R3 and R4 together with the carbon atoms to which they are attached form a saturated or unsaturated 5- or 6-membered ring, said ring being optionally substituted with a C1-C4 hydrocarbon group, and R5 represents a C1-C6 hydrocarbon group, comprising reacting, at a temperature which does not exceed about 5° C., a metallated indene of formula II with a disubstituted hydrocarbon of formula III: wherein R1, R2, R3, R4, and R5 have the same meaning as defined above, M represents a metal ion, and X independently represents a suitable leaving group, in a suitable reaction medium wherein the molar ratio of II to III is 2.05 or higher. The process is particularly suitable for preparing bisindenylethane, i.e., R1-R4 represent H and R5 represents an ethylene group.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: July 2, 2002
    Assignee: Akzo Nobel NV
    Inventors: Richard Herman Woudenberg, Faysal Kalmoua
  • Process for preparing bisindenylalkanes
    Publication number: 20010037043
    Abstract: The present invention relates to a process for preparing bisindenylalkanes of formula I: 1
    Type: Application
    Filed: February 22, 2001
    Publication date: November 1, 2001
    Inventors: Richard Herman Woudenberg, Faysal Kalmoua