Patents by Inventor Fayza Daboussi

Fayza Daboussi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MUTANT YEAST STRAIN CAPABLE OF PRODUCING MEDIUM CHAIN FATTY ACIDS
    Publication number: 20200017892
    Abstract: Embodiments of the present disclosure relate to mutant yeast strains, in particular mutant Yarrowia strains, capable of producing medium chain fatty acids compared to the parent oleaginous yeast strain from which said mutant oleaginous yeast strain derives. Embodiments of the present disclosure also relate to means and methods for obtaining these mutant yeast strains.
    Type: Application
    Filed: January 8, 2018
    Publication date: January 16, 2020
    Applicants: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Florence Bordes, Coraline Rigouin, Alain Marty, Marc Gueroult, Isabelle Andre, Sophie Barbe, Benjamin Percheron, Christian Croux, Fayza Daboussi
  • Modified diatoms for biofuel production
    Patent number: 10087453
    Abstract: The invention provides engineered diatoms and methods of producing oil using diatoms. The invention also provides methods of modifying the lipids quantity and/or quality produced by diatom organisms through genome engineering. Also provided are oils, fuels, oleochemicals, chemical precursors, and other compounds manufactured from such modified diatoms.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 2, 2018
    Assignee: CELLECTIS
    Inventors: Philippe Duchateau, Fayza Daboussi, David Sourdive, Jean-Charles Epinat
  • METHODS AND KITS FOR DETECTING NUCLEIC ACID SEQUENCES OF INTEREST USING DNA-BINDING PROTEIN DOMAIN
    Publication number: 20160355875
    Abstract: The present invention relates to a method for the detection of a specific nucleic acid. Specifically, the invention provides a method and kits for detecting the presence of a specific nucleic acid using engineered DNA-binding domains such as Transcription Activator Like-Effector (TALE) domain or modular base-per-base binding domains (MBBBD). The method of the invention is particularly useful for in vitro diagnostic application.
    Type: Application
    Filed: October 10, 2014
    Publication date: December 8, 2016
    Inventors: Julien VALTON, Alexandre JUILLERAT, Fayza DABOUSSI, Marine BEURDELEY, Claudia BERTONATI, Philippe DUCHATEAU
  • NEW METHOD OF SELECTION OF ALGAL-TRANSFORMED CELLS USING NUCLEASE
    Publication number: 20160312233
    Abstract: The invention relates to a method to select transformed cells. In particular, the present invention relates to the use of a nuclease engineered to inactivate selectable marker which confers cell resistance to a toxic compound. The present invention relates to methods of modifying genome of a cell, preferably an algal cell comprising the present selection step. The present invention also relates to specific engineered nucleases, polynucleotides, vectors encoding thereof, kits and isolated cells comprising said nuclease.
    Type: Application
    Filed: December 12, 2014
    Publication date: October 27, 2016
    Inventors: Philippe DUCHATEAU, Fayza DABOUSSI
  • CAS9 NUCLEASE PLATFORM FOR MICROALGAE GENOME ENGINEERING
    Publication number: 20160304893
    Abstract: The present invention relates to a method of genome engineering in microalgae using the Cas9/CRISPR system. In particular, the present invention relates to methods of delivering RNA guides via cell penetrating peptides in microalgae, preferably in stable integrated Cas9 microalgae. The present invention also relates to kits and isolated cells comprising Cas9, split Cas9 or guide RNA and Cas9-fused cell-penetrating peptides. The present invention also relates to isolated cells obtained by the methods of the invention.
    Type: Application
    Filed: December 12, 2014
    Publication date: October 20, 2016
    Inventors: Fayza DABOUSSI, Marine BEURDELEY, Alexandre JUILLERAT
  • METHOD FOR TARGETED MODIFICATION OF ALGAE GENOMES
    Publication number: 20160272980
    Abstract: The invention relates to a method for modifying genetic material in algal cells that includes the use of rare-cutting endonuclease to target specific genomic sequences. In particular, the invention relates to a method for modifying genetic material in algal cells wherein rare-cutting endonuclease, especially a homing endonuclease or a TALE-Nuclease, is expressed over several generations to efficiently modify said target genome sequences.
    Type: Application
    Filed: November 18, 2013
    Publication date: September 22, 2016
    Inventors: Philippe DUCHATEAU, Fayza DABOUSSI
  • MODIFIED DIATOMS FOR BIOFUEL PRODUCTION
    Publication number: 20160130599
    Abstract: The invention provides engineered diatoms and methods of producing oil using diatoms. The invention also provides methods of modifying the lipids quantity and/or quality produced by diatom organisms through genome engineering. Also provided are oils, fuels, oleochemicals, chemical precursors, and other compounds manufactured from such modified diatoms.
    Type: Application
    Filed: June 25, 2014
    Publication date: May 12, 2016
    Inventors: Philippe DUCHATEAU, Fayza DABOUSSI, David SOURDIVE, Jean-Charles EPINAT
  • METHOD FOR IMPROVING CLEAVAGE OF DNA BY ENDONUCLEASE SENSITIVE TO METHYLATION
    Publication number: 20130196320
    Abstract: The present invention concerns novel methods for improving cleavage of DNA by rare-cutting endonucleases, overcoming DNA modification constraints, particularly DNA methylation, thereby giving new tools for genome engineering, particularly to increase the integration efficiency of a transgene into a genome at a predetermined location, including therapeutic applications and cell line engineering.
    Type: Application
    Filed: June 15, 2011
    Publication date: August 1, 2013
    Applicant: CELLECTIS
    Inventors: Philippe Duchateau, Julien Valton, Fayza Daboussi