Abstract: The disclosure provides a preparation method for a novel biocompatible antibacterial bacterial cellulose Fmoc-F hydrogel, belonging to the technical field of biomedical gels. The preparation method is characterized by comprising the following steps of (1) preparing a bacterial cellulose (BC) homogenate, (2) mixing the bacterial cellulose with an Fmoc-F solution, and preparing the bacterial cellulose/Fmoc-F antibacterial hydrogel by means of in-situ chemical crosslinking. The preparation method has the advantages of rapid gelling reaction, simple reaction system, high gel plasticity and the like. Because of the bacterial cellulose, the antibacterial hydrogel prepared in the disclosure has high mechanical strength. Meanwhile, compared with traditional micro-molecular antibacterial materials, the bacterial cellulose/Fmoc-F antibacterial hydrogels prepared in the disclosure have broad-spectrum antibacterial effects and good biocompatibility.

Abstract: Provided is a formulation including chitosan impregnated with a modified clay. The modified clay is a smectite clay modified with cations. The formulation is effective for healing a burn wound. It is superior in skin regeneration and patient comfort than commonly available clinical treatments. The formulation can be used for the treatment of dermal wounds including burn, incision, excision, and abrasion wounds.