Patents by Inventor Federica Simeoni

Federica Simeoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for delivering siRNA into mammalian cells
    Patent number: 8354387
    Abstract: Complex comprising a peptide carrier of SEQ ID NO:1 GALFLGFLGAAGSTMGAWSQPKR1KRKVR2 and an appropriate siRNA, wherein R1 represents any amino acid residue and more preferably K or S, R2 is null or represents one of the following groups: cysteamide, cysteine, thiol, amide, linear or ramified C1-C6 alkyl optionally substituted, primary or secondary amine, osidic derivative, lipid, phospholipid or cholesterol and said siRNA is selected to silence a target mRNA.
    Type: Grant
    Filed: February 23, 2009
    Date of Patent: January 15, 2013
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Gilles Divita, May Catherine Morris, Frédéric Heitz, Federica Simeoni
  • Methods and Compositions for Delivering siRNA into Mammalian Cells
    Publication number: 20090258926
    Abstract: Complex comprising a peptide carrier of SEQ ID NO:1 GALFLGFLGAAGSTMGAWSQPKR1KRKVR2 and an appropriate siRNA, wherein R1 represents any amino acid residue and more preferably K or S, R2 is null or represents one of the following groups: cysteamide, cysteine, thiol, amide, linear or ramified C1-C6 alkyl optionally substituted, primary or secondary amine, osidic derivative, lipid, phospholipid or cholesterol and said siRNA is selected to silence a target mRNA.
    Type: Application
    Filed: February 23, 2009
    Publication date: October 15, 2009
    Applicant: Centre National De La Recherche Scientifique
    Inventors: Gilles Divita, May Catherine Morris, Frederic Heitz, Federica Simeoni
  • Peptide carrier for delivering siRNA into mammalian cells
    Patent number: 7514530
    Abstract: Complex comprising a peptide carrier of SEQ ID NO:1 GALFLGFLGAAGSTMGAWSQPKR1KRKVR2 and an appropriate siRNA, wherein R1 represents any amino acid residue and more preferably K or S, R2 is null or represents one of the following groups: cysteamide, cysteine, thiol, amide, linear or ramified C1-C6 alkyl optionally substituted, primary or secondary amine, osidic derivative, lipid, phospholipid or cholesterol and said siRNA is selected to silence a target mRNA.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: April 7, 2009
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Gilles Divita, May Catherine Morris, Frédéric Heitz, Federica Simeoni
  • Methods and compositions for delivering siRNA into mammalian cells
    Publication number: 20050239687
    Abstract: Complex comprising a peptide carrier of SEQ ID NO:1 GALFLGFLGAAGSTMGAWSQPKR1KRKVR2 and an appropriate siRNA, wherein R1 represents any amino acid residue and more preferably K or S, R2 is null or represents one of the following groups: cysteamide, cysteine, thiol, amide, linear or ramified C1-C6 alkyl optionally substituted, primary or secondary amine, osidic derivative, lipid, phospholipid or cholesterol and said siRNA is selected to silence a target mRNA.
    Type: Application
    Filed: April 26, 2004
    Publication date: October 27, 2005
    Inventors: Gilles Divita, May Morris, Frederic Heitz, Federica Simeoni