Patents by Inventor Federico Carlos Arejola Gaeta
Federico Carlos Arejola Gaeta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11925625Abstract: A method of treating chemical-induced lung injury in a subject in need thereof includes administering to the subject a therapeutically effective amount of ibudilast, or a pharmaceutical salt thereof.Type: GrantFiled: January 27, 2022Date of Patent: March 12, 2024Assignee: MediciNova, Inc.Inventors: Kazuko Matsuda, Federico Carlos Aréjola Gaeta
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Publication number: 20240016729Abstract: A injectable pharmaceutical compositions consists of a buffered aqueous solution comprising (a) about 5% w/v to about 15% w/v sulfobutylether-?-cyclodextrin (SBE-?-CD), and about 0.05% w/v to about 0.5% w/v ibudilast, or (b) about 5% w/v to about 25% w/v polyoxyl castor oil, and about 1% w/v to about 5% w/v ibudilast.Type: ApplicationFiled: July 12, 2023Publication date: January 18, 2024Applicant: MediciNova, Inc.Inventors: Kazuko MATSUDA, Federico Carlos Aréjola Gaeta, Yuichi IWAKI
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Patent number: 11865214Abstract: This disclosure is directed to ibudilast higher dosage oral formulations, such as tablet or capsule formulations, and the corresponding methods of treatment.Type: GrantFiled: September 21, 2020Date of Patent: January 9, 2024Assignee: MediciNova, Inc.Inventors: Kazuko Matsuda, Federico Carlos Aréjola Gaeta
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Publication number: 20230304071Abstract: Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Kits include the composition disposed in a portion of a biological sample collection apparatus.Type: ApplicationFiled: April 17, 2023Publication date: September 28, 2023Inventor: Federico Carlos Arejola Gaeta
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Publication number: 20230272368Abstract: Disclosed are nucleic acid preserving compositions and methods of manufacturing and using the same, particularly for detection of COVID-19 virus. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Kits include the composition disposed in a portion of a biological sample collection apparatus. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Detection of COVID-19 virus is demonstrated. Compositions also preserve and stabilize human nucleic acid for subsequent analysis.Type: ApplicationFiled: April 14, 2021Publication date: August 31, 2023Inventors: Federico Carlos Arejola Gaeta, William Phillips
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Patent number: 11655495Abstract: Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Kits include the composition disposed in a portion of a biological sample collection apparatus.Type: GrantFiled: September 14, 2020Date of Patent: May 23, 2023Assignee: Spectrum Solutions L.L.C.Inventor: Federico Carlos Arejola Gaeta
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Publication number: 20230116096Abstract: A method of preventing metastasis of a cancer in a patient in need thereof includes administering to the patient a therapeutically effective amount of ibudilast, or a pharmaceutical salt thereof.Type: ApplicationFiled: July 25, 2022Publication date: April 13, 2023Applicant: MEDICINOVA, INC.Inventors: Kazuko Matsuda, Federico Carlos Aréjola Gaeta
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Publication number: 20220241252Abstract: A method of treating chemical-induced lung injury in a subject in need thereof includes administering to the subject a therapeutically effective amount of ibudilast, or a pharmaceutical salt thereof.Type: ApplicationFiled: January 27, 2022Publication date: August 4, 2022Applicant: MediciNova, Inc.Inventors: Kazuko Matsuda, Federico Carlos Aréjola Gaeta
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Publication number: 20210085613Abstract: This disclosure is directed to ibudilast higher dosage oral formulations, such as tablet or capsule formulations, and the corresponding methods of treatment.Type: ApplicationFiled: September 21, 2020Publication date: March 25, 2021Applicant: MediciNova, Inc.Inventors: Kazuko Matsuda, Federico Carlos Aréjola Gaeta
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Publication number: 20200407777Abstract: Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Kits include the composition disposed in a portion of a biological sample collection apparatus.Type: ApplicationFiled: September 14, 2020Publication date: December 31, 2020Inventor: Federico Carlos Arejola Gaeta
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Patent number: 10774368Abstract: Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Kits include the composition disposed in a portion of a biological sample collection apparatus.Type: GrantFiled: October 31, 2018Date of Patent: September 15, 2020Assignee: Spectrum Solutions L.L.C.Inventor: Federico Carlos Arejola Gaeta
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Publication number: 20190062806Abstract: Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Kits include the composition disposed in a portion of a biological sample collection apparatus.Type: ApplicationFiled: October 31, 2018Publication date: February 28, 2019Inventor: Federico Carlos Arejola Gaeta
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Patent number: 10174362Abstract: Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Kits include the composition disposed in a portion of a biological sample collection apparatus.Type: GrantFiled: January 16, 2018Date of Patent: January 8, 2019Assignee: Spectrum Solutions L.L.C.Inventor: Federico Carlos Arejola Gaeta
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Publication number: 20180201977Abstract: Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, an acid, and a mucolytic agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include water, guanidine thiocyanate, Tris, EDTA, SLS, SDA 3C, HCl, and N-acetyl-L-cysteine. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid and contacting the biological sample with the composition. Kits include the composition disposed in a portion of a biological sample collection apparatus.Type: ApplicationFiled: January 16, 2018Publication date: July 19, 2018Inventor: Federico Carlos Arejola Gaeta