Abstract: A field operating policy for a subsurface region is optimized by setting initial policy parameters for the subsurface region. Fluid flow within a subsurface region is simulated, wherein the simulation includes optimizing an objective function for field operating policy, the objective function corresponding simultaneously to the modeled fluid flow characteristics of one or more wellbores within the subsurface region and relating to at least one production system performance parameter. Optimizing the objective function for field operating policy may include optimizing the initial policy parameters for the subsurface region with an over time optimization technique, wherein the policy parameters are optimized for a predetermined policy period. An enhanced value of the objective function is determined at each timestep within the predetermined policy period.