Patents by Inventor Federico FIGLIOLINI

Federico FIGLIOLINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of extracellular vesicles (EVs) from biological fluid samples
    Patent number: 11484816
    Abstract: The invention relates to compositions and methods for isolating extracellular vesicles (EVs) from a biological fluid sample. The compositions and methods of the invention are based on the combination of a polycation with an extracellular matrix forming polymer. Extracellular vesicles (EVs) are isolated from biological fluids such as blood, serum, plasma, saliva, urine or cerebrospinal fluid, or from the conditioned medium of a cell culture, such as an adult stem cell culture. The use of the isolation methods and compositions of the invention results in a higher EVs recovery, enrichment in exosomes, simplicity, cost-effectiveness, and in the isolation of EVs that retain their biological activities in vitro.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: November 1, 2022
    Assignee: UNICYTE EV AG
    Inventors: Maria Chiara Deregibus, Federico Figliolini, Ciro Tetta, Giovanni Camussi
  • ISOLATION OF EXTRACELLULAR VESICLES (EVS) FROM BIOLOGICAL FLUID SAMPLES
    Publication number: 20200179827
    Abstract: The invention relates to compositions and methods for isolating extracellular vesicles (EVs) from a biological fluid sample. The compositions and methods of the invention are based on the combination of a polycation with an extracellular matrix forming polymer. Extracellular vesicles (EVs) are isolated from biological fluids such as blood, serum, plasma, saliva, urine or cerebrospinal fluid, or from the conditioned medium of a cell culture, such as an adult stem cell culture. The use of the isolation methods and compositions of the invention results in a higher EVs recovery, enrichment in exosomes, simplicity, cost-effectiveness, and in the isolation of EVs that retain their biological activities in vitro.
    Type: Application
    Filed: April 11, 2017
    Publication date: June 11, 2020
    Applicant: UNICYTE EV AG
    Inventors: Maria Chiara DEREGIBUS, Federico FIGLIOLINI, Ciro TETTA, Giovanni CAMUSSI