Patents by Inventor Federico Gassa

Federico Gassa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of Crisaborole in a stable crystal form
    Patent number: 11325922
    Abstract: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: May 10, 2022
    Assignee: OLON S.P.A.
    Inventors: Federico Gassa, Lazzaro Feliciani, Alberto Mazza, Marco Quaroni, Mara Sada, Giorgio Bertolini
  • A PROCESS FOR THE PREPARATION OF CRISABOROLE
    Publication number: 20210070781
    Abstract: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
    Type: Application
    Filed: June 25, 2018
    Publication date: March 11, 2021
    Inventors: Federico GASSA, Lazzaro FELICIANI, Alberto MAZZA, Marco QUARONI, Mara SADA, Giorgio BERTOLINI
  • PROCESS FOR THE PREPARATION OF CRISABOROLE IN A STABLE CRYSTAL FORM
    Publication number: 20200407377
    Abstract: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
    Type: Application
    Filed: July 10, 2020
    Publication date: December 31, 2020
    Inventors: Federico GASSA, Lazzaro FELICIANI, Alberto MAZZA, Marco QUARONI, Mara SADA, Giorgio BERTOLINI
  • PROCESS FOR THE PREPARATION OF CRISABOROLE
    Publication number: 20190194230
    Abstract: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
    Type: Application
    Filed: March 21, 2018
    Publication date: June 27, 2019
    Inventors: Federico GASSA, Lazzaro FELICIANI, Alberto MAZZA, Marco QUARONI, Mara SADA, Giorgio BERTOLINI
  • Process for the preparation of crisaborole
    Patent number: 10329311
    Abstract: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: June 25, 2019
    Assignee: OLON S.P.A.
    Inventors: Federico Gassa, Lazzaro Feliciani, Alberto Mazza, Marco Quaroni, Mara Sada, Giorgio Bertolini
  • Process for the preparation of indanamine derivatives and new synthesis intermediates
    Patent number: 10059653
    Abstract: Subject-matter of the invention is a process for the preparation of a key intermediate in the synthesis of indacaterol. Subject-matter of the invention are also new synthesis intermediates.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: August 28, 2018
    Assignee: OLON S.P.A.
    Inventors: Giorgio Bertolini, Paolangelo Cerea, Corrado Colli, Lazzaro Feliciani, Federico Gassa, Aldo Bianchi, Federica Colombo, Stefano Maiorana, Filippo Nisic
  • PROCESS FOR THE PREPARATION OF INDANAMINE DERIVATIVES AND NEW SYNTHESIS INTERMEDIATES
    Publication number: 20170362161
    Abstract: Subject-matter of the invention is a process for the preparation of a key intermediate in the synthesis of indacaterol. Subject-matter of the invention are also new synthesis intermediates.
    Type: Application
    Filed: January 19, 2016
    Publication date: December 21, 2017
    Applicant: OLON S.P.A.
    Inventors: Giorgio BERTOLINI, Paolangelo CEREA, Corrado COLLI, Lazzaro FELICIANI, Federico GASSA, Aldo BIANCHI, Federica COLOMBO, Stefano MAIORANA, Filippo NISIC
  • Process for the preparation of isoserine derivatives
    Patent number: 8624051
    Abstract: This invention relates to a “one pot” process for the preparation of isoserine derivatives in high diastereoselective way. The process according to the invention includes the steps of reacting a protected glycidic acid with imines to yield isoserines protected both at the —OH and at the —COOH groups, deprotection of the obtained intermediates to isoserines or isoserine 1-4C— alkyl esters. Pure threo derivatives as the main isomer are obtained.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: January 7, 2014
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Maria Luisa Gelmi, Federico Gassa
  • PROCESS FOR THE PREPARATION OF ISOSERINE DERIVATIVES
    Publication number: 20130090493
    Abstract: This invention relates to a “one pot” process for the preparation of isoserine derivatives in high diastereoselective way. The process according to the invention includes the steps of reacting a protected glycidic acid with imines to yield isoserines protected both at the —OH and at the —COOH groups, deprotection of the obtained intermediates to isoserines or isoserine 1-4C— alkyl esters. Pure threo derivatives as the main isomer are obtained.
    Type: Application
    Filed: April 13, 2011
    Publication date: April 11, 2013
    Applicant: INDENA S.P.A
    Inventors: Gabriele Fontana, Maria Luisa Gelmi, Federico Gassa