Patents by Inventor Federico Goodsaid

Federico Goodsaid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS, COMPOSITIONS, AND KITS FOR NUCLEIC ACID ANALYSIS
    Publication number: 20170101674
    Abstract: Aspects of the disclosure relate to methods and kits for assessing cancer. Some aspects of the disclosure relate to methods and kits for preparing a sample library for sequencing. Some aspects of the disclosure relate to methods and kits for allele detection. Some aspects of the disclosure relate to high efficiency ligation methods and kits. Some aspects of the disclosure relate to sensitive detection of amplicons.
    Type: Application
    Filed: August 19, 2016
    Publication date: April 13, 2017
    Inventors: Austin So, Michael Y. Lucero, Francisco M. De La Vega, Federico Goodsaid
  • Determination of a Genotype of an Amplification Product at Multiple Allelic Sites
    Publication number: 20120053069
    Abstract: A method is provided for genotyping a target sequence at at least two allelic sites by a 5? nuclease amplification reaction. In one embodiment, the method includes performing a nucleic acid amplification on a target sequence having at least two different allelic sites using a nucleic acid polymerase having 5?-3? nuclease activity and a primer capable of hybridizing to the target sequence in the presence of two or more sets of allelic oligonucleotide probes wherein at least all but one of the allelic oligonucleotide probes include a different fluorescer than the other probes and a quencher positioned on the probe to quench the fluorescence of the fluorescer; detecting a fluorescence spectrum of the amplification; calculating a fluorescence contribution of each fluorescer to the fluorescence spectrum; and determining a presence or absence of the different allelic variants based on the fluorescence contribution of each fluorescer to the combined fluorescence spectrum.
    Type: Application
    Filed: November 13, 2009
    Publication date: March 1, 2012
    Applicant: Applied Biosystems, LLC
    Inventors: Kenneth J. LIVAK, Federico Goodsaid
  • Thermal reaction device and method for using the same
    Patent number: 7867454
    Abstract: An M.times.N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: January 11, 2011
    Assignee: Fluidigm Corporation
    Inventors: Federico Goodsaid, Marc Unger, Jiang Huang, Emerson Quan
  • Thermal Reaction Device and Method for Using the Same
    Publication number: 20080292504
    Abstract: An M.times.N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.
    Type: Application
    Filed: October 30, 2007
    Publication date: November 27, 2008
    Applicant: Fluigm Corporation
    Inventors: Federico Goodsaid, Marc Unger, Jiang Huang, Emerson Quan
  • Determination of genotype of an amplification product at multiple allelic sites
    Publication number: 20080187913
    Abstract: A method is provided for genotyping a target sequence at least two allelic sites by a 5? nuclease amplification reaction.
    Type: Application
    Filed: November 3, 2006
    Publication date: August 7, 2008
    Applicant: Applera Corporation
    Inventors: Kenneth J. Livak, Federico Goodsaid
  • Determination of a genotype of an amplification product at multiple allelic sites
    Patent number: 7132239
    Abstract: A method is provided for genotyping a target sequence at at least two allelic sites by a 5? nuclease amplification reaction.
    Type: Grant
    Filed: June 4, 2003
    Date of Patent: November 7, 2006
    Assignee: Applera Corporation
    Inventors: Kenneth J. Livak, Federico Goodsaid
  • Thermal reaction device and method for using the same
    Publication number: 20050145496
    Abstract: An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block.
    Type: Application
    Filed: June 23, 2004
    Publication date: July 7, 2005
    Inventors: Federico Goodsaid, Marc Unger, Jiang Huang, Emerson Quan
  • Determination of a genotype of an amplification product at multiple allelic sites
    Patent number: 6884583
    Abstract: A method is provided for genotyping a target sequence at at least two allelic sites by a 5? nuclease amplification reaction.
    Type: Grant
    Filed: March 21, 2002
    Date of Patent: April 26, 2005
    Assignee: Applera Corporation
    Inventors: Kenneth J. Livak, Federico Goodsaid
  • Determination of a genotype of an amplification product at multiple allelic sites
    Publication number: 20040053302
    Abstract: A method is provided for genotyping a target sequence at at least two allelic sites by a 5′ nuclease amplification reaction.
    Type: Application
    Filed: June 4, 2003
    Publication date: March 18, 2004
    Inventors: Kenneth J. Livak, Federico Goodsaid
  • Determination of a genotype of an amplification product at multiple allelic sites
    Publication number: 20020164630
    Abstract: A method is provided for genotyping a target sequence at at least two allelic sites by a 5′ nuclease amplification reaction.
    Type: Application
    Filed: March 21, 2002
    Publication date: November 7, 2002
    Inventors: Kenneth J. Livak, Federico Goodsaid
  • Computer logic for fluorescence genotyping at multiple allelic sites
    Patent number: 6154707
    Abstract: A method is provided for genotyping a target sequence at at least two allelic sites by a 5' nuclease amplification reaction. In one embodiment, the method includes performing a nucleic acid amplification on a target sequence having at least two different allelic sites using a nucleic acid polymerase having 5'.fwdarw.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: November 28, 2000
    Assignee: PE Applied Biosystems, a division of Perkin-Elmer
    Inventors: Kenneth J. Livak, Federico Goodsaid
  • Determination of a genotype of an amplification product at multiple allelic sites
    Patent number: 5962233
    Abstract: A method is provided for genotyping a target sequence at at least two allelic sites by a 5' nuclease amplification reaction. In one embodiment, the method includes performing a nucleic acid amplification on a target sequence having at least two different allelic sites using a nucleic acid polymerase having 5'.fwdarw.
    Type: Grant
    Filed: February 4, 1998
    Date of Patent: October 5, 1999
    Assignee: The Perkin-Elmer Corporation
    Inventors: Kenneth J. Livak, Federico Goodsaid