Patents by Inventor Federico Graf

Federico Graf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11918611
    Abstract: The present invention is directed to a bacterial, preferably probiotic bacterial peptidoglycan hydrolase (PGH), a peptidoglycan hydrolase (PGH)-comprising bacterial, preferably probiotic bacterial strain or a peptidoglycan hydrolase (PGH)-comprising composition for use in the therapeutic or prophylactic treatment of a bacterial infection, preferably for the treatment of a bacterial infection resulting in diarrhea. Further aspects of the present invention relate to corresponding methods for preparing a medicament and to a corresponding method of treatment.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: March 5, 2024
    Assignee: CRIGASSENI AG
    Inventor: Federico Graf
  • Patent number: 11235060
    Abstract: The invention relates to compositions for vaginal or, alternatively, oral administration and to the use of such compositions for stabilizing the vaginal, or, alternatively, the intestinal acidity and establishing favorable conditions for the inhibition of pathogens and the growth of lactobacilli in the urogenital, or, alternatively, gastro-intestinal tract.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: February 1, 2022
    Assignee: PROBIOSWISS AG
    Inventor: Federico Graf
  • Patent number: 11040076
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: June 22, 2021
    Assignee: PROBIOSWISS AG
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20210077543
    Abstract: The present invention is directed to a bacterial, preferably probiotic bacterial peptidoglycan hydrolase (PGH), a peptidoglycan hydrolase (PGH)-comprising bacterial, preferably probiotic bacterial strain or a peptidoglycan hydrolase (PGH)-comprising composition for use in the therapeutic or prophylactic treatment of a bacterial infection, preferably for the treatment of a bacterial infection resulting in diarrhea. Further aspects of the present invention relate to corresponding methods for preparing a medicament and to a corresponding method of treatment.
    Type: Application
    Filed: May 2, 2019
    Publication date: March 18, 2021
    Inventor: Federico Graf
  • Publication number: 20200046837
    Abstract: The invention relates to compositions for vaginal or, alternatively, oral administration and to the use of such compositions for stabilizing the vaginal, or, alternatively, the intestinal acidity and establishing favorable conditions for the inhibition of pathogens and the growth of lactobacilli in the urogenital, or, alternatively, gastro-intestinal tract.
    Type: Application
    Filed: November 30, 2017
    Publication date: February 13, 2020
    Inventor: FEDERICO GRAF
  • Publication number: 20190142878
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Application
    Filed: January 14, 2019
    Publication date: May 16, 2019
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Patent number: 10213466
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: February 26, 2019
    Assignee: Probioswiss Ag
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20170027998
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Application
    Filed: October 12, 2016
    Publication date: February 2, 2017
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20100196340
    Abstract: Useful probiotics have been selected among lactic acid bacteria strains of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within urogenital and/or gastrointestinal epithelial cells in humans. Probiotic compositions comprise at least one of the said lactic acid bacteria strains in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.
    Type: Application
    Filed: October 17, 2005
    Publication date: August 5, 2010
    Applicant: BDN BIO SARL
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20080131462
    Abstract: The invention relates to a method for preventing or treating gastrointestinal infections in humans, which comprises administering a pharmaceutical preparation comprising, in combination with a pharmaceutically acceptable or food grade carrier, a therapeutically effective amount of at least one lactic acid bacteria strain of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii selected for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within gastrointestinal epithelial cells.
    Type: Application
    Filed: April 20, 2007
    Publication date: June 5, 2008
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart
  • Publication number: 20080019954
    Abstract: The invention relates to a method for preventing or treating urogenital infections in females, which comprises administering a pharmaceutical preparation comprising, in combination with a suitable galenical carrier, a therapeutically effective amount of at least one lactic acid bacteria strain of the genus L. acidophilus, L. crispatus, L. gasseri, L. helveticus and L. jensenii selected for their ability to kill urogenital and/or gastrointestinal pathogens and their ability to inhibit internalization of urogenital and/or gastrointestinal pathogens within vaginal epithelial cells, as well as for their ability to modulate a humoral and/or cellular immune response at the vaginal and/or gastrointestinal level, in particular to inhibit the inflammatory syndrome as well as the infectious syndrome.
    Type: Application
    Filed: April 20, 2007
    Publication date: January 24, 2008
    Inventors: Federico Graf, Philipp Grob, Dominique Brassart