Patents by Inventor Federico Medda

Federico Medda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAYTANSINOID-BASED DRUG DELIVERY SYSTEMS
    Publication number: 20230391794
    Abstract: The present subject matter provides for albumin-binding prodrugs, maytansinoid-based compounds, and uses thereof.
    Type: Application
    Filed: December 21, 2022
    Publication date: December 7, 2023
    Inventors: Felix Kratz, Khalid Abu Ajaj, Anna Warnecke, Friederike I. Nollmann, Stephan David Koester, Javier Garcia Fernandez, Lara Pes, Heidi-Kristin Walter, Johannes Pall Magnusson, Serghei Chercheja, Patricia Perez Galan, Federico Medda, Steffen Josef Daum
  • KINASE MODULATORS AND METHODS OF USE THEREOF
    Publication number: 20230373985
    Abstract: The present invention relates to novel compounds that modulate the activity of one or more kinases, such as TYK2 or mutants thereof. The compounds, which may be kinase inhibitors or activators, are useful for treating autoimmune diseases, such as, such as psoriasis, lupus, multiple sclerosis, and inflammatory bowel disease.
    Type: Application
    Filed: July 12, 2021
    Publication date: November 23, 2023
    Inventors: Roland KOESTLER, Nasser Yehia, Jean Tassel, Marcus Wegmann, Federico Medda, Patricia Perez-Gallan, Christiane Gilch, Michael Thormann, Andreas Treml, Michael Almstetter, Zhonghua Pei, Scott Savage
  • Maytansinoid-based drug delivery systems
    Patent number: 11572373
    Abstract: The present subject matter provides for albumin-binding prodrugs, maytansinoid-based compounds, and uses thereof.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: February 7, 2023
    Assignee: LADRX CORPORATION
    Inventors: Felix Kratz, Khalid Abu Ajaj, Anna Warnecke, Friederike I. Nollmann, Stephan David Koester, Javier Garcia Fernandez, Lara Pes, Heidi-Kristin Walter, Johannes Pall Magnusson, Serghei Chercheja, Patricia Perez Galan, Federico Medda, Steffen Josef Daum
  • Albumin-binding prodrugs of auristatin E derivatives
    Patent number: 11377473
    Abstract: The present disclosure provides for albumin-binding prodrugs of auristatin E derivatives and uses thereof.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: July 5, 2022
    Assignee: CENTURION BIOPHARMA CORPORATION
    Inventors: Felix Kratz, Khalid Abu Ajaj, Anna Warnecke, Friederike I. Nollmann, Stephan David Koester, Javier Garcia Fernandez, Lara Pes, Heidi-Kristin Walter, Johannes Pall Magnusson, Serghei Chercheja, Patricia Perez Galan, Federico Medda, Steffen Josef Daum
  • IMAGING AGENTS FOR RADIOLABELING EXOGENOUS AND ENDOGENOUS ALBUMIN
    Publication number: 20210353783
    Abstract: The present disclosure provides albumin-binding radioactive metal complexes and uses thereof, including diagnosing and treating disease.
    Type: Application
    Filed: July 16, 2019
    Publication date: November 18, 2021
    Inventors: Felix Kratz, Khalid Abu Ajaj, Anna Warnecke, Friederike I. Nollmann, Stephan David Koester, Javier Garcia Fernandez, Lara Pes, Steffen Daum, Johannes Pall Magnusson, Serghei Chercheja, Patricia Perez Galan, Federico Medda
  • ALBUMIN-BINDING PRODRUGS OF AURISTATIN E DERIVATIVES
    Publication number: 20200385421
    Abstract: The present disclosure provides for albumin-binding prodrugs of auristatin E derivatives and uses thereof.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 10, 2020
    Inventors: Felix Kratz, Khalid Abu Ajaj, Anna Warnecke, Friederike I. Nollmann, Stephan David Koester, Javier Garcia Fernandez, Lara Pes, Heidi-Kristin Walter, Johannes Pall Magnusson, Serghei Chercheja, Patricia Perez Galan, Federico Medda, Steffen Josef Daum
  • MAYTANSINOID-BASED DRUG DELIVERY SYSTEMS
    Publication number: 20200385403
    Abstract: The present subject matter provides for albumin-binding prodrugs, maytansinoid-based compounds, and uses thereof.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 10, 2020
    Inventors: Felix Kratz, Khalid Abu Ajaj, Anna Warnecke, Friederike I. Nollmann, Stephan David Koester, Javier Garcia Fernandez, Lara Pes, Heidi-Kristin Walter, Johannes Pall Magnusson, Serghei Chercheja, Patricia Perez Galan, Federico Medda, Steffen Josef Daum
  • Pyrimidine derivatives and their pharmaceutical use
    Patent number: 8563557
    Abstract: The invention provides a compound according to formula (I): wherein: X is O or S; Y is O or S; each Ar and Ar? is independently a mono-, bi- or tricyclic aryl or heteroaryl group optionally substituted with one or more substituents selected from halo, alkyl, aryl, heteroaryl, hydroxyl, nitro, amino, alkoxy, alkylthio, cyano, thio, ester, acyl and amido; each R2 is independently hydrogen, halo, alkyl, aryl, heteroaryl, hydroxyl, nitro, amino, alkoxy, alkylthio, cyano and thio; and R1 is as defined herein, or a physiologically acceptable salt, solvate, ester, amide or other physiologically functional derivative thereof.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: October 22, 2013
    Assignees: University Court of the University of Dundee, University Court of the University of St Andrews
    Inventors: Nicholas James Westwood, Sonia Lain, Federico Medda
  • Compounds
    Publication number: 20110245282
    Abstract: The invention provides a compound according to formula (I): wherein: X is O or S; Y is O or S; each Ar and Ar? is independently a mono-, bi- or tricyclic aryl or heteroaryl group optionally substituted with one or more substituents selected from halo, alkyl, aryl, heteroaryl, hydroxyl, nitro, amino, alkoxy, alkylthio, cyano, thio, ester, acyl and amido; each R2 is independently hydrogen, halo, alkyl, aryl, heteroaryl, hydroxyl, nitro, amino, alkoxy, alkylthio, cyano and thio; and R1 is as defined herein, or a physiologically acceptable salt, solvate, ester, amide or other physiologically functional derivative thereof.
    Type: Application
    Filed: October 2, 2009
    Publication date: October 6, 2011
    Inventors: Nicholas James Westwood, Sonia Lain, Federico Medda