Patents by Inventor Fedor Nikolaievich Dultsev

Fedor Nikolaievich Dultsev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Measurement and use of molecular interactions
    Patent number: 7763475
    Abstract: The present invention is based on the realization that the bonds between a target molecule, or a target molecule attached to a particle, and a surface, can be ruptured by mechanically oscillating the surface at increasing amplitude, leading to detachment of the target molecule or particle from the surface. The required acceleration, and hence force, will depend on a variety of factors, including the mass of the molecule or particle, the nature of the bond to the surface and the geometric shape or size of the target molecule or particle. The present invention may therefore be used to separate or to size different target molecules, or to detect their presence.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: July 27, 2010
    Assignee: Inverness Medical Switzerland GmbH
    Inventors: David Klenerman, Victor Petrovich Ostanin, Fedor Nikolaievich Dultsev, Matthew Cooper
  • Measurement and use of molecular interactions
    Patent number: 7195909
    Abstract: The subject invention pertains to a method for determining the affinity between binding partners, or a property of one of the binding partners dependent on the affinity, comprising the steps of: (i) contacting the binding partners, one of which is immobilised on a surface; (ii) oscillating the surface at increasing amplitude; and (iii) detecting a dissociation event. An analogous method can be used to separate a target analyte from a composition. The subject invention also pertains to an apparatus for determining the affinity between binding partners, and comprises: a surface (10) having one binding partner (16) immobilised thereon; means for oscillating the surface at increasing amplitude; and means (14, 15) for detecting a dissociation event.
    Type: Grant
    Filed: January 24, 2003
    Date of Patent: March 27, 2007
    Assignee: Akubio Limited
    Inventors: David Klenerman, Victor Petrovich Ostanin, Fedor Nikolaievich Dultsev
  • Measurement and use of molecular interactions
    Publication number: 20030194697
    Abstract: The subject invention pertains to a method for determining the affinity between binding partners or a property of one of the binding partners dependent on the affinity, comprising the step of:
    Type: Application
    Filed: January 24, 2003
    Publication date: October 16, 2003
    Inventors: David Klenerman, Victor Petrovich Ostanin, Fedor Nikolaievich Dultsev
  • Measurement and use of molecular interactions
    Patent number: 6589727
    Abstract: A method for determining the affinity between binding partners, or a property of one of the binding partners dependent on the affinity, comprising the steps of: (i) contacting the binding partners, one of which is immobilised on a surface; (ii) oscillating the surface at increasing amplitude; and (iii) detecting a dissociation event. An analogous method can be used to separate a target analyte from a composition. The subject invention also pertains to an apparatus for determining the affinity between binding partners, and comprises: a surface (10) having one binding partner (16) immobilised thereon; means for oscillating the surface at increasing amplitude; and a device (14, 15) for detecting a dissociation event.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: July 8, 2003
    Assignee: Akubio Ltd.
    Inventors: David Klenerman, Victor Petrovich Ostanin, Fedor Nikolaievich Dultsev