Abstract: The present application relates to a salt of a pyranose-substituted heterocyclic compound, a preparation method therefor, and use thereof, and in particular, to an acid addition salt of a compound of formula (I) or a prodrug thereof, and further relates to D-glucuronate of a crystalline compound of formula (I) or a prodrug thereof D-glucuronate of a crystalline compound of formula (II) has particular advantages in terms of crystallizability, subsequent purification, stability, formulation medicinal properties or quality control, and is most applicable for improving the formulation pharmaceutical properties, purity and quality control, as well as large-scale process development of such drugs.

Abstract: The present invention relates to a maleate salt of a compound represented by formula I, a method for preparing the salt, a pharmaceutical composition containing the salt, and the use of the salt. The present invention also relates to crystalline forms C, D and E of the maleate salt of the compound represented by formula I, methods for preparing the crystalline forms, crystalline compositions and pharmaceutical compositions containing the crystalline forms, and uses thereof.

Abstract: Provided herein is a method of using threonate to alter cellular physiology, such as neuronal physiology. A method of the present disclosure may include providing to a medium comprising a cell, a threonate-containing compound, or a precursor thereof, to increase the concentration of threonate in the medium, where the increased concentration of threonate is sufficient to increase the concentration of magnesium in the cell. Also provided is a method that includes administering a threonate-containing compound, or a precursor thereof, to an individual, to increase synaptic density in the brain and/or to treat a neurological disorder, e.g., cognitive impairment. The threonate-containing compound of the present disclosure does not include magnesium threonate.

Abstract: A central processing unit (CPU) hot-remove method, including determining, by a controller of a server that has a non-full mesh first CPU topology comprising multiple CPUs, a first CPU of the multiple CPUs to be removed from the first CPU topology according to first indication information, determining at least one second CPU associated in the first CPU topology with the first CPU, where the at least one second CPU and the first CPU meet a preset condition associated with a relationship between the first CPU and the at least one second CPU, and sending second indication information to the first CPU topology, the second indication information instructing the first CPU topology to remove the first CPU and the at least one second CPU, resulting in a second CPU topology without the first CPU and other than the at least one second CPU.

Abstract: A bridged silicone resin is disclosed which has the general formula (1): (HSiO3/2)x(RSiO3/2)y(R1SiO3/2)z(SiO3/2—X—SiO3/2)s; wherein x and s are each from >0 to <1 and 0<y+z<1 such that x+y+z+s=1; R is independently an alkyl group; R1 is independently an aryl group; and X is divalent group comprising a silarylene group or a —(CH2)qSiR2R3[O(SiR2R3O)n]SiR2R3—(CH2)q?— group, where n is an integer from 1 to 10, each R2 and R3 is an independently selected substituted or unsubstituted hydrocarbyl group, and q and q? are each independently integers selected from 0 or from 1 to 6. Various methods relating to the bridged silicone resin and end uses thereof are also disclosed.

Abstract: Provided are computer program product, system, and method for loading dependency library files from a shared library repository in an application runtime environment. A determination is made of a dependency tree of dependency library files for an application to load into an application runtime environment. A determination is made as to whether a shared library repository includes all the dependency library files in the dependency tree. The shared library repository is updated to include any dependency library files not in the dependency tree of the application. Access is provided to the dependency library files in the shared library repository in the dependency tree in the application runtime environment. The application is started in the application runtime environment in response to providing access to the dependency library files in the application runtime environment.

Abstract: Systems and methods for embodiments of a graph based artificial intelligence systems for identity management are disclosed. Embodiments of the identity management systems disclosed herein may utilize a network graph approach to analyzing identities or entitlements of a distributed networked enterprise computing environment. Specifically, in certain embodiments, an artificial intelligence based identity management systems may utilize the peer grouping of an identity graph (or peer grouping of portions or subgraphs thereof) to identify roles from peer groups or the like.

Abstract: A mechanical linkage structure for linking a chair and a seat, comprises a first link, a second link, and a third link respectively used as a driven link, a fourth link used as a driving link, a fifth link, a sixth link, and a seventh link respectively used as a driven link. The first link is pivotally connected to the second link and the third link, respectively; the second link is pivotally connected to the fourth link and the fifth link, respectively; the third link is pivotally connected to the fourth link, the fifth link, and the seventh link, respectively; the fifth link is pivotally connected to the sixth link; the sixth link is pivotally connected to the seventh link; the fourth link is driven to rotate the first link, the second link, the third link, the fifth link, the sixth link and the seventh link, to realize the unfolding or collapse of the mechanical linkage structure.

Abstract: In one example an electrical connector is disclosed, which may include a housing and a plurality of electrical contacts disposed in the housing for engaging with corresponding connecting terminals provided on a flat circuit. The housing may include a front portion defining an elongated opening and a rear portion opposite the front portion. The rear portion may define a visible area. The flat circuit may be inserted in the housing from the elongated opening and extended into the visible area.

Abstract: A polymer composite includes a linear aliphatic semi-crystalline polyamide having on average 10 to 14 carbon atoms in the monomer units, or the compound thereof, an S glass fiber, and a core-shell impact modifier. The polymer composite can achieve higher stiffness and impact strength without impairing the transparency significantly. The polymer composite can be used as molding material.

Abstract: A chair according to the present invention includes: a leg 1; a leg support pole 13; a support base 4; a movement mechanism 5 located below a seat 2, the movement mechanism 5 provided with plural movement parts 5A, 5B configured to allow the seat 2 to move in a certain area along a predetermined trajectory in a front-rear and left-right directions between the support base 4 and the seat 2, the movement mechanism 5 being a support mechanism configured to support the seat 2 so that the seat 2 moves in the front-rear direction and left-right directions; and plural cover members 71, 72 arranged corresponding to the plural movement parts 5A, 5B. The plural cover members 71, 72 are configured to move relatively in accordance with movement of the plural movement parts 5A, 5B and cover the support mechanism 5.

Abstract: The present application belongs to the field of medicinal chemistry, and relates to crystals of an aniline pyrimidine compound serving as an EGFR inhibitor. Specifically, the present application relates to crystal A, crystal B and crystal C of N-(2-((2-(dimethyl amino)ethyl)(methyl)amino)-4-methoxy-5-(4-(3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-1-base)pyrimidine-2-base amino)phenyl)acrylamide (formula I) hydrochloride, and also relates to the method for preparing the crystal A, the crystal B and the crystal C, a crystal composition comprising the crystal A, the crystal B, and the crystal C, a pharmaceutical composition comprising the crystal A, the crystal B and the crystal C or the crystal composition thereof, and medical uses thereof. The crystal A, the crystal B and the crystal C in the present application has the advantages of high purity, high crystallization degree, good stability and the like.

Abstract: A processing system comprises a chamber body, a substrate support and a lid assembly. The substrate support is located in the chamber body and comprises a first electrode. The lid assembly is positioned over the chamber body and defines a processing volume. The lid assembly comprises a faceplate, a second electrode positioned between the faceplate and the chamber body, and an insulating member positioned between the second electrode and the processing volume. A power supply system is coupled to the first electrode and the faceplate and is configured to generate a plasma in the processing volume.

Abstract: A method, including: 1) inputting a multi-story point cloud, and segmenting a story and an inter-story connection region based on an elevation histogram of the point cloud in a vertical direction; 2) segmenting rooms for each story based on a grid map projected onto an XOY plane respectively, wherein the XOY plane is parallel to a flooring; 3) segmenting indoor space cells for each story based on a vector wall line respectively; constructing a vector indoor plan based on superimposition of the vector and the grid for each story respectively; and 5) establishing a three-dimensional model of a multi-story structure by deleting an overlapping surface between the story and the connection region according to the Boolean intersection.

Abstract: An automated apparatus for pre-processing of nucleic acid detection includes a reagent plate to place sample and pre-processing reagent; a base for placing the reagent plate provided with a temperature control module and a blending module; a magnetic separation module for magnetic particles separation, cleaning and elution; a pipetting device for transferring the reagent in the reagent plate comprising a pipetting module, a rotation module and a pipetting tip; a mobile rail platform for supporting the pipetting device; and a host computer for controlling the temperature control module, rotation module, blending module, magnetic separation module and pipetting module. The automated apparatus for pre-processing of nucleic acid detection of the present invention can execute full automation of pre-processing of nucleic acid detection including extraction, library construction and product purification. The final product can be directly used in the unattended operation of high-throughput sequencing.

Abstract: The present disclosure provides a battery module and a battery pack. The battery pack comprises a box and a battery module, the battery module is accommodated in the box. The battery module comprises batteries sequentially arranged in a first direction. The battery comprises an electrode assembly, a case and a cap assembly, the electrode assembly is received in the case, and the cap assembly is connected with the case. The case comprises two first side walls, and the two first side walls are respectively positioned at two sides of the electrode assembly in the first direction. The first side walls of two adjacent batteries face each other. An area of the first side wall is defined as S1, a distance between the electrode assemblies of two adjacent batteries in the first direction is defined as D, S1 and D satisfying a relationship: 1.2×10?5 mm?1?D/S1?500×10?5 mm31 1.

Abstract: A method for transferring components from a transfer head to a receiving substrate is disclosed. The method includes monitoring signals indicative of a pitch mismatch between locations on the transfer head and locations on the receiving substrate and actuating at least one actuator based at least in part on the monitored signals to reduce the mismatch of the pitch of the locations on the transfer head and the locations on the receiving substrate.

Abstract: Disclosed by the present invention is a sub-band selection activation-based multi-band hyperbolic frequency modulation spread spectrum underwater acoustic communication method. The present invention discloses: dividing the available bandwidth of an underwater acoustic system into a plurality of sub-bands, performing hyperbolic frequency modulation on each of the sub-bands respectively, and performing spread spectrum modulation on the plurality of sub-bands within the same frequency modulation period, thus implementing multi-band parallel transmission. Hence, within each frequency modulation period, the divided plurality of sub-bands is grouped, and each sub-band group activates different sub-bands for transmission according to different options for transmitting data. Compared to other underwater acoustic hyperbolic frequency modulation communication solutions, the present invention further improves the frequency band utilization of the system, and the energy efficiency is also improved.

Abstract: A 25-hydroxycholecalciferol monohydrate crystal, a preparation method thereof, and a microemulsion using the 25-hydroxycholecalciferol monohydrate crystal. The X-ray powder diffraction spectrum of the 25-hydroxycholecalciferol monohydrate crystal of the present disclosure shows characteristic peaks at 2? of 10.035°, 11.623°, 14.631°, 15.054°, 15.551°, 16.471°, 17.198°, 19.002°, 19.628°, 20.109°, 21.886°, 23.113°, 23.661°, 24.701°, 25.220°, 25.440°, and 28.527°. The 25-hydroxycholecalciferol monohydrate crystal can effectively enhance the stability of 25-hydroxycholecalciferol, and is more beneficial to the production and storage of related preparations, and thus biological characteristics of 25-hydroxycholecalciferol can be effectively utilized.

Abstract: This application provides a photovoltaic power generation system. The system includes at least one first photovoltaic module, a photovoltaic inverter, a first two-way DC/DC converter, and at least one first energy storage unit, and further includes at least one second photovoltaic module or at least one second energy storage unit. The photovoltaic inverter includes a DC/DC converter and a DC-AC inverter, where the DC/DC converter is electrically connected to the at least one first photovoltaic module, and the DC/DC converter is connected to the DC-AC inverter through a direct current bus. For the photovoltaic power generation system, photovoltaic arrays and energy storage devices can be configured flexibly to cope with peaks and troughs of power consumption.