Patents by Inventor Fei Guo
Fei Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250136974Abstract: The present invention relates to a nucleic acid molecule capable of blocking motor protein, a library containing the nucleic acid molecule, a method for constructing the nucleic acid molecule or library containing the same, and an application of the nucleic acid molecule or library containing same.Type: ApplicationFiled: December 31, 2021Publication date: May 1, 2025Inventors: Ou Wang, Xiao Shi, Xun Xu, Wenwei Zhang, Fei Guo, Siyu Bao, Yuliang Dong, Tao Zeng
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Publication number: 20250120020Abstract: Systems, methods, and apparatus are described herein for maintaining high signal integrity and high bandwidth in data transmissions between an integrated circuit package and a PCB. The integrated circuit package has multiple layers. Signal pins for connecting the integrated circuit package, both physically and electrically, to the PCB are located at a first layer. A signal trace is coupled to each signal pin. The signal trace bifurcates into two branches and couples to a given signal pin at the distal end of each branch.Type: ApplicationFiled: October 10, 2024Publication date: April 10, 2025Inventors: Fei Guo, Muhammad Ershadul Kabir, Suresh Chandrasekhar
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Publication number: 20250066748Abstract: The present invention provides a helicase BCH2X, comprising an amino acid sequence represented by any one of SEQ ID NOs: 1-3. The present invention also provides a complex structure comprising the helicase BCH2X and a binding moiety for binding polynucleotides. The present invention also provides a use of the helicase BCH2X or the complex structure comprising same in the control and characterization of polynucleotides and single-molecule nanopore sequencing.Type: ApplicationFiled: December 31, 2021Publication date: February 27, 2025Inventors: Lele Wang, Tao Zeng, Zhenjun Liu, Junyi Chen, Ziyu Zhao, Denghui Li, Fei Guo, Zhouxiang Ji, Ou Wang, Yuxiang Li, Yuliang Dong, Wenwei Zhang, Xun Xu
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Publication number: 20250066747Abstract: Provided is helicase BCH1X, which comprises an amino acid sequence represented by SEQ ID NO: 1 or 2. Further provided are a complex structure comprising helicase BCH1X and a binding moiety used for binding to a polynucleotide, and a use thereof in the control and characterization of a polynucleotide and in single molecule nanopore sequencing.Type: ApplicationFiled: December 31, 2021Publication date: February 27, 2025Inventors: Xun Xu, Fei Guo, Qiaoxia Hu, Denghui Li, Junyi Chen, Lele Wang, Ziyu Zhao, Zhouxiang Ji, Tao Zeng, Ou Wang, Yuxiang Li, Yuliang Dong, Wenwei Zhang
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Patent number: 12222326Abstract: A material testing machine, including a machine body, a first fixing element, a second fixing element and a detection assembly; the first and the second fixing elements are mounted to the machine body, the first fixing element is configured to mount a first testing element, and the second fixing element is configured to mount a second testing element; in a first state, the first and the second testing elements are in sliding contact; in a second state, the first fixing element drives the first testing element to collide with the second testing element; the detection assembly is configured to detect a target parameter, and in the first state, the target parameter includes a friction force and/or, a friction sound between the first and the second testing elements; and in the second state, the target parameter includes a collision force received by the first or the second testing element.Type: GrantFiled: July 19, 2022Date of Patent: February 11, 2025Assignee: TSINGHUA UNIVERSITYInventors: Fei Guo, Ganlin Cheng, Bingzhe Chen, Chong Xiang, Yijie Huang, Shengshan Chen, Yongjian Li, Xiaohong Jia, Yuming Wang
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Patent number: 12217150Abstract: A data processing method and apparatus based on a recurrent neural network and a device are provided. The recurrent neural network includes multiple recurrent units, each recurrent unit includes multiple data processing nodes and a start node, at least one recurrent unit includes an end node, and at least one data processing node is included between the start node and the end node. During the processing of the first target processing object in a first recurrent unit, in a case that the first target processing object does not satisfy the first preset condition, the start node in the first recurrent unit is run to add a tag to the data processing nodes subsequent to the start node and stop addition of the tag in response to reaching the end node, and no processing is performed by the data processing nodes with the tag.Type: GrantFiled: January 11, 2021Date of Patent: February 4, 2025Assignee: Beijing Baidu Netcom Science and Technology Co., LTDInventors: Huihuang Zheng, Xiang Lan, Yamei Li, Liujie Zhang, Fei Guo, Yanjun Ma, Dianhai Yu
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Patent number: 12174083Abstract: An equipment for sealing-performance test includes a housing, a fixed mechanism and a detection part; the housing is configured to accommodate the fixed mechanism, and an abutting part is formed in the housing and is configured to abut against an outer side of a sealing ring; the fixed mechanism includes a central rod, a plurality of fixed blocks and a driving assembly, the central rod extends along a direction parallel to the axial direction of the central rod, the plurality of fixed blocks are evenly disposed along a circumferential direction of the central rod, and the driving assembly is configured to drive the plurality of fixed blocks to move along a radial direction of the central rod; a test cavity and a detection cavity are formed in the housing, the test cavity is filled with a test fluid, and is separated from the detection cavity by the sealing ring.Type: GrantFiled: July 12, 2022Date of Patent: December 24, 2024Assignee: TSINGHUA UNIVERSITYInventors: Fei Guo, Yijie Huang, Chong Xiang, Ganlin Cheng, Shengshan Chen, Xiaohong Jia, Yuming Wang
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Publication number: 20240418603Abstract: A performance testing device for the piston rod sealing assembly includes a bracket, a support apparatus, a drive apparatus and a leakage detection apparatus, where the support apparatus includes a cylinder body that is internally provided with a movable channel, and the movable channel is configured to allow a piston rod equipped with a sealing component to pass therethrough; the drive apparatus is provided on the bracket and configured to be connected with the piston rod; the leakage detection apparatus includes a limit member and an oil receiver, the limit member is provided with a detection channel and an oil channel and connected to the cylinder body, the detection channel is communicated with the movable channel and configured to allow the piston rod to pass therethrough; one end of the oil channels is communicated with the detection channel and the other end thereof is communicated with the oil receiver.Type: ApplicationFiled: September 8, 2023Publication date: December 19, 2024Applicant: Tsinghua UniversityInventors: Fei GUO, Chong XIANG, Yijie HUANG, Fan ZHANG, Yu TIAN, Yuming WANG
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Patent number: 12104984Abstract: Embodiments of the present disclosure belong to the field of valve sealing, and in particular, relate to a test device for simulating sealing performance of a one-way valve. A box is provided with a gas inlet pipe and a gas outlet pipe, the gas inlet pipe is communicated with a gas source, a detection device is communicated with the gas outlet pipe, the detection device is used to detect detection gas input into the box by the gas source, a sleeve is connected to the gas inlet pipe, one end of the sleeve is communicated with the gas source, the other end of the sleeve has a gas outlet, one end of a fitting piece is used to block the gas outlet, and the other end of the fitting piece is connected to a driving member, which is used to drive the fitting piece to move and rotate.Type: GrantFiled: May 24, 2022Date of Patent: October 1, 2024Assignee: Tsinghua UniversityInventors: Fei Guo, Qiyao Chen, Chong Xiang, Yijie Huang, Ganlin Cheng, Fan Zhang, Xiaohong Jia
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Publication number: 20240267248Abstract: Various embodiments of the teachings herein include a device searching method. An example method may include: acquiring fingerprint information of a first device in a first network; acquiring fingerprint information of each device in a second network; for each device in the second network, calculating a similarity between the fingerprint information of said device and the fingerprint information of the first device; and according to all the calculated similarities, judging whether the first device should be a device in the second network.Type: ApplicationFiled: May 26, 2022Publication date: August 8, 2024Applicant: Siemens AktiengesellschaftInventors: Wei Dong Huang, Jing Jing Fang, Xin Yue Liu, Dai Fei Guo
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Publication number: 20240219279Abstract: Provided is a testing apparatus for friction and wear, which includes a testing mechanism, a controller, a lubrication system, a cooling system, a loading system, and a detection system. The controller is communicatively connected to the testing mechanism. The lubrication system is adapted to be in communication with the testing mechanism and communicatively connected to the controller. The cooling system is adapted to be in communication with the testing mechanism. The loading system is adapted to be in communication with the testing mechanism and communicatively connected to the controller. The detection system is adapted to be connected to the testing mechanism and communicatively connected to the controller.Type: ApplicationFiled: March 15, 2024Publication date: July 4, 2024Inventors: Ying LIU, Haoran LIAO, Zhurong LIANG, Anqi HUANG, Hongju LI, Xiang ZHAO, Weifeng HUANG, Yongjian LI, Fei GUO
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Publication number: 20240220686Abstract: Disclosed are urban-region road network vehicle-passage flow prediction method and system based on a hybrid deep learning model. The method comprises: compiling statistics on traffic flow on the basis of vehicle-passage data of a checkpoint; performing spatial and temporal distribution feature analysis on vehicle-passage flow data of the checkpoint, and performing feature extraction according to an analysis result, so as to acquire a spatial and temporal influence factor; constructing and training a ConvLSTM and BILSTM hybrid deep learning model according to the spatial and temporal influence factor; performing synchronous prediction on traffic flow of an urban-region road network, selecting prediction loss functions and evaluation indicators, and performing visual representation on a result; and calculating a traffic flow variation degree by means of a linear time series prediction model Prophet, and performing traffic state identification, so as to realize traffic state pre-determination.Type: ApplicationFiled: May 16, 2022Publication date: July 4, 2024Applicant: NANJING NORMAL UNIVERSITYInventors: Hong ZHANG, Xin XU, Fei GUO, Huandong WANG
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Publication number: 20240200040Abstract: A chimeric DNA polymerase includes: a first fragment having at least 80% homology to at least part of an N-end domain of KOD DNA polymerase; a second fragment having at least 80% homology to at least part of an exonucleolytic domain of Pab DNA polymerase; a third fragment having at least 80% homology to at least part of the N-end domain of KOD DNA polymerase; a fourth fragment having at least 80% homology to at least part of a palm domain of Pfu DNA polymerase; a fifth fragment having at least 80% homology to at least part of a finger domain of Pab DNA polymerase; a sixth fragment having at least 80% homology to at least part of the palm domain of Pfu DNA polymerase; and a seventh fragment having at least 80% homology to at least part of a thumb domain of KOD DNA polymerase.Type: ApplicationFiled: December 23, 2019Publication date: June 20, 2024Inventors: Qun AN, Miaomiao GUO, Feng XI, Fei GUO, Yue ZHENG, Yuliang DONG, Wenwei ZHANG
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Publication number: 20240201047Abstract: The present disclosure provides a measuring device and measuring method for a shaft-holding force of a seal, relating to the technical field of sealing. The measuring device of a shaft-holding force of a seal includes a driving assembly, a first pressing plate, a pressure sensor, an adiabatic rod, a conical shaft, a first support, a second support, a test box and a seal, a working temperature of the seal may be simulated by the test box, the conical shaft is located inside the test box, the pressure sensor is located outside the test box, the adiabatic rod is connected between the pressure sensor and the conical shaft, and the pressure sensor and the conical shaft are in different environments. Through separating the pressure sensor from the test box by the adiabatic rod, a temperature of the test box will not affect the pressure sensor.Type: ApplicationFiled: June 9, 2023Publication date: June 20, 2024Applicant: Tsinghua UniversityInventors: Fei GUO, Fan ZHANG, Chong XIANG, Yijie HUANG, Ganlin CHENG, Yajie WAN, Xiaohong JIA
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Publication number: 20240173206Abstract: Provided is a wearable transcutaneous electrical acupoint stimulation physiotherapy device for preventing and treating postoperative cognitive dysfunction, including a head-mounted wearable device, a hand wearable device and a knee wearable device; where the head-mounted wearable device includes a forehead-shaped piece, a head coronal plane adjustable ring elastic belt, a head sagittal plane adjustable ring elastic belt, a first slidable electrode fixing block, a first electrode pad and a first sliding guide groove.Type: ApplicationFiled: November 6, 2023Publication date: May 30, 2024Inventors: Changjun GAO, Fei GUO, Ruili HAN, Li SUN, Yuan QIN
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Publication number: 20240109863Abstract: The present invention provides a 2-pyridone derivative having a structure represented by formula I, or a stereoisomer or pharmaceutically acceptable salt thereof. Activity experiment results show that the 2-pyridone derivative provided in the present invention has higher activity and selectivity, and can be used to treat thyroid hormone receptor-related diseases.Type: ApplicationFiled: December 28, 2021Publication date: April 4, 2024Applicants: KPC PHARMACEUTICALS, INC, SHANGHAI KUNHENG PHARMA-TECH CO., LTDInventors: Hejun LV, Peng WANG, Fei GUO, Shaoqing CHEN, Junfeng LIU
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Patent number: 11912867Abstract: Described herein is a polyurethane having an isocyanate group and having C—C double bonds on a side chain, a process for preparing such a polyurethane, and an UV-moisture dual cure polyurethane reactive hotmelt including the polyurethane.Type: GrantFiled: January 14, 2020Date of Patent: February 27, 2024Assignee: BASF SEInventors: Xuyuan Peng-Poehler, Yun Fei Guo, Li Chen
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Publication number: 20230408371Abstract: An equipment for sealing-performance test includes a housing, a fixed mechanism and a detection part; the housing is configured to accommodate the fixed mechanism, and an abutting part is formed in the housing and is configured to abut against an outer side of a sealing ring; the fixed mechanism includes a central rod, a plurality of fixed blocks and a driving assembly, the central rod extends along a direction parallel to the axial direction of the central rod, the plurality of fixed blocks are evenly disposed along a circumferential direction of the central rod, and the driving assembly is configured to drive the plurality of fixed blocks to move along a radial direction of the central rod; a test cavity and a detection cavity are formed in the housing, the test cavity is filled with a test fluid, and is separated from the detection cavity by the sealing ring.Type: ApplicationFiled: July 12, 2022Publication date: December 21, 2023Inventors: Fei Guo, Yijie Huang, Chong Xiang, Ganlin Cheng, Shengshan Chen, Xiaohong Jia, Yuming Wang
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Patent number: 11848656Abstract: A power delivery network, circuit, and method reduce die package resonance of an integrated circuit (IC) die. Decoupling capacitors interact with equivalent series inductances (ESLs) of power conductors within a package carrier substrate create the die package resonance characteristic. In one form an anti-resonance tuning circuit has a first branch including a first inductance coupled to one of an IC die positive power supply conductor and an IC die negative power supply conductor, and a second branch coupled directly to a selected one of a carrier substrate positive or negative conductive structures, the second branch comprising a second inductance inductively coupled to the first inductance.Type: GrantFiled: June 24, 2021Date of Patent: December 19, 2023Assignee: ATI Technologies ULCInventor: Fei Guo
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Patent number: 11843639Abstract: Various embodiments include an industrial control system security analysis method. The method may include: collecting a communication data packet of interactive data transmitted between control devices in a first industrial control system; extracting network identifiable information; and determining whether it matches a pre-created event database. If the information matches: determining that the communication data packet is a malicious data packet; acquiring security policies of the first industrial control system and a second industrial control system; and determining a threat coefficient of the communication data packet for the second industrial control system based on the network identifiable information and each of the security policies, wherein the threat coefficient represents a degree of threat of the communication data packet to the second industrial control system.Type: GrantFiled: May 29, 2020Date of Patent: December 12, 2023Assignee: SIEMENS LTD., CHINAInventor: Dai Fei Guo