Patents by Inventor Fei Hong

Fei Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210147826
    Abstract: Provided is a method for large-scale preparation of a purified preparation of a recombinant lentiviral vector at the GMP grade. The method comprises: (a) providing raw material feed liquid to be purified that comprises recombinant viral vectors; (b) carrying out a microfiltration treatment on the feed liquid to obtain a microfiltered filtrate comprising the recombinant viral vectors; (c) optionally concentrating the filtrate to obtain a concentrated filtrate; (d) purifying the filtrate obtained in the previous step by means of chromatography to obtain a crude pure product comprising the recombinant viral vectors; and (e) subjecting the crude pure product obtained in the previous step to liquid exchange and elaborate purification to obtain the purified recombinant viral vectors.
    Type: Application
    Filed: September 28, 2020
    Publication date: May 20, 2021
    Inventors: Yi HONG, Ting YAN, Jiangguo YING, Haojie ZHANG, Li ZHANG, Fei WANG, Dijun ZHAO, Luyi ZHANG
  • Publication number: 20210151519
    Abstract: A display substrate, a manufacturing method of the display substrate and a display device are provided. The display substrate includes a plurality of sub-pixels arranged in an array in a display area. The display area includes a boundary extending in non-straight line. The plurality of sub-pixels arranged in the array include a plurality of first sub-pixels whose distances to the boundary extending in non-straight line are less than a preset threshold and a plurality of second sub-pixels other than the plurality of first sub-pixels, where at least one of the first sub-pixels is smaller in area than each of the second sub-pixels.
    Type: Application
    Filed: April 17, 2019
    Publication date: May 20, 2021
    Inventors: Lei Lv, Bo Han, Fei Xu, Jie Gao, Jun Hong, Jiuyang Zhu, Mingwei Zhang, JIngyong Li, Chunmin Xu
  • Publication number: 20210026925
    Abstract: The present disclosure relates to a method and a device for categorizing multimedia resources. The method includes: counting the numbers of icons for respective types of icons input by a user for a multimedia resource; and determining a category to which the multimedia resource belongs according to the numbers of the respective types of icons input for the multimedia resource. The method and device for categorizing multimedia resources according to the present disclosure can take respective types of icons input by the user for the multimedia resources into consideration when categorizing the multimedia resources, thereby improving the accuracy of the categorization of the multimedia resources.
    Type: Application
    Filed: March 1, 2018
    Publication date: January 28, 2021
    Inventors: Diyang Han, Yi Fang, Fei Hong, Jiang Chang
  • Patent number: 10818819
    Abstract: A micro light emitting device including a component layer, a first electrode and a second electrode is provided. The component layer includes a main body and a protruding structure disposed on the main body. The first electrode is electrically connected to the component layer. The second electrode is electrically connected to the component layer. The first electrode, the second electrode and the protruding structure are disposed on the same side of the main body. The protruding structure is located between the first electrode and the second electrode. A connection between the first electrode and the second electrode traverses the protruding structure. The main body has a surface. The protruding structure has a first height with respect to the surface. Any one of the first electrode and the second electrode has a second height with respect to the surface. The relation 0.8?H1/H2?1.2 is satisfied, wherein H1 is the first height and H2 is the second height.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: October 27, 2020
    Assignee: PixeLED Display CO., LTD.
    Inventors: Pai-Yang Tsai, Fei-Hong Chen, Yi-Chun Shih
  • Publication number: 20200231702
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Application
    Filed: November 21, 2019
    Publication date: July 23, 2020
    Inventors: Leslie Ann GREENE, Kyle P. CHIANG, Fei HONG, Alain P. VASSEROT, Wing-Sze LO, Jeffry D. Watkins, Cheryl L. QUINN, John D. Mendlein
  • Patent number: 10717786
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: July 21, 2020
    Assignees: aTye Pharma, Inc., Pangu BioPharma Limited
    Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
  • Publication number: 20200222484
    Abstract: Disclosed is a total flavonoids extract of Gynura formosana Kitam., containing 80%-85% of rutin by weight percent content. The results of pharmacological experiments show that the extract can lower the activity of xanthine oxidase in the liver of a hyperuricemia model mouse and reduce the synthesis of uric acid to a certain degree and has a certain uric acid-lowering effect, and can be used as a potential drug for treating hyperuricemia or gout. The method for preparing the total flavonoids extract of Gynura formosana Kitam. comprises: after an extraction step, selecting a complex enzyme composed of enzymes with a specific composition and a specific ratio for enzymolosis, and further carrying out the step of extracting and concentrating with macroporous resin and isolating and purifying with macroporous resin, so that the HPLC purity of rutin in the resulting total flavonoids extract of Gynura formosana Kitam. reaches 80%-85%.
    Type: Application
    Filed: March 17, 2020
    Publication date: July 16, 2020
    Inventors: Huijun Yuan, Tingting Yin, Fei Hong, Juan Yu, Jinxiang Zeng, Shicong Wang
  • Publication number: 20200223942
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Application
    Filed: November 21, 2019
    Publication date: July 16, 2020
    Inventors: Leslie Ann GREENE, Kyle P. CHIANG, Fei HONG, Alain P. VASSEROT, Wing-Sze LO, Jeffry D. Watkins, Cheryl L. QUINN, John D. Mendlein
  • Publication number: 20200215141
    Abstract: A total flavonoid extract from Gynura formosana Kitam., comprising 80-85% of rutin. A preparation method comprises selecting a complex enzyme consisting of a specific composition and ratio of enzymes for enzymatic hydrolysis, extracting and concentrating by a macroporous resin, and separating and purifying by a macroporous resin. The extract has therapeutic effect on non-alcoholic fatty liver disease.
    Type: Application
    Filed: March 17, 2020
    Publication date: July 9, 2020
    Inventors: Zhiliang Chen, Jinming Huang, Juan Yu, Fei Hong, Zhaoqiang Zhang, Xuxin Li
  • Publication number: 20200215140
    Abstract: A total flavonoid extract from Gynura formosana Kitam., comprising, in weight percent, 80-85% of rutin. A method for preparing the total flavonoid extract from Gynura formosana Kitam. comprises solvent extraction, complex enzymatic hydrolysis, and separation and purification by a macroporous resin. The total flavonoid extract from Gynura formosana Kitam. is used to prepare a drug or health product related to alcoholic fatty liver disease.
    Type: Application
    Filed: March 17, 2020
    Publication date: July 9, 2020
    Inventors: Zhiliang Chen, Jinming Huang, Fei Hong, Juan Yu, Zhiyi Luo, Xuxin Li
  • Publication number: 20200172632
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Application
    Filed: September 27, 2019
    Publication date: June 4, 2020
    Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
  • Patent number: 10669533
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: June 2, 2020
    Assignees: aTyr Pharma, Inc., Pangu BioPharma Limited
    Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry Dean Watkins, Cheryl L. Quinn, John D. Mendlein
  • Publication number: 20200140571
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Application
    Filed: September 13, 2019
    Publication date: May 7, 2020
    Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
  • Publication number: 20200055956
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Application
    Filed: July 1, 2019
    Publication date: February 20, 2020
    Inventors: Leslie Ann GREENE, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
  • Patent number: 10563191
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: February 18, 2020
    Assignees: aTyr Pharma, Inc., Pangu BioPharma Limited
    Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
  • Patent number: 10563192
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: February 18, 2020
    Assignees: aTyr Pharma, Inc., Pangu BioPharma Limited
    Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain P. Vasserot, Wing-Sze Lo, Jeffry D. Watkins, Cheryl L. Quinn, John D. Mendlein
  • Publication number: 20200028028
    Abstract: A micro light emitting device including a component layer, a first electrode and a second electrode is provided. The component layer includes a main body and a protruding structure disposed on the main body. The first electrode is electrically connected to the component layer. The second electrode is electrically connected to the component layer. The first electrode, the second electrode and the protruding structure are disposed on the same side of the main body. The protruding structure is located between the first electrode and the second electrode. A connection between the first electrode and the second electrode traverses the protruding structure. The main body has a surface. The protruding structure has a first height with respect to the surface. Any one of the first electrode and the second electrode has a second height with respect to the surface. The relation 0.8?H1/H2?1.2 is satisfied, wherein H1 is the first height and H2 is the second height.
    Type: Application
    Filed: September 26, 2018
    Publication date: January 23, 2020
    Applicant: PixeLED Display CO., LTD.
    Inventors: Pai-Yang Tsai, Fei-Hong Chen, Yi-Chun Shih
  • Publication number: 20200012701
    Abstract: The disclosure relates to a method and an apparatus for recommending an associated user. In one embodiment a method comprises determining a first interactive attribute of a first user based on first interactive data of the first user in a multimedia resource playing process; determining interactive relevance between the first user and a second user according to the first interactive attribute and a second interactive attribute of the second user; and recommending, according to the interactive relevance, the second user associated with the first user. Embodiments according to the disclosure can determine an interactive attribute based on interactive data, determine interactive relevance between a first user and a second user according to the interactive attribute, and further recommend the second user associated with the first user, thereby recommending associated users based on user behavior, improving the accuracy in recommending associated users, and enhancing user experience.
    Type: Application
    Filed: November 24, 2017
    Publication date: January 9, 2020
    Inventors: Diyang HAN, Yi FANG, Fei HONG
  • Publication number: 20200007944
    Abstract: The disclosure relates to methods and apparatuses for displaying interactive attributes. The method comprises: determining interactive attributes regarding a multimedia resource based on interactive data of a user during playback of the multimedia resource; generating visualized interactive information based on the interactive attributes; and displaying the visualized interactive information. According to embodiments of the disclosure, interactive attributes can be determined based on interactive data of a user during playback of a multimedia resource, and then visualized interactive information is generated and displayed, to clearly and intuitively display interactions, improve the display effect, and enhance user experience.
    Type: Application
    Filed: November 24, 2017
    Publication date: January 2, 2020
    Inventors: Diyang HAN, Yi FANG, Fei HONG, Feng ZHANG
  • Publication number: 20190379942
    Abstract: The disclosure relates to methods and apparatuses for processing multimedia resources. In one embodiment, a method comprises: obtaining a time distribution of one or more icons entered by one or more users with respect to multimedia resources; determining a specific period of the multimedia resources based on the time distribution; and in response to a request for the specific period from a user, executing an operation corresponding to the request on the multimedia resources corresponding to the specific period. Since icons can reflect viewing reactions of the user, the specific period obtained by the disclosed embodiments can be used to effectively segment multimedia resources based on a user reaction, facilitating rapid obtaining of a segment of interest by the user and improving the viewing experience of the user and efficiency of the device processing the multimedia resources.
    Type: Application
    Filed: November 24, 2017
    Publication date: December 12, 2019
    Inventors: Diyang HAN, Yi FANG, Fei HONG, Aobo ZHANG