Abstract: The present invention provides recombinant monoclonal antibodies that bind to the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2 or COVID-19) spike protein, and methods of use. In various embodiments of the invention, the antibodies are fully human antibodies that bind to SARS-CoV-2 spike protein. In some embodiments, the antibodies of the invention are useful for inhibiting or neutralizing SARS-CoV-2 activity, thus providing a means of treating or preventing COVID-19 infection in humans. In some embodiments, the invention provides for a combination of one or more antibodies that bind to the SARS-CoV-2 spike protein for use in treating COVID-19 infection. In certain embodiments, the one or more antibodies bind to distinct non-competing epitopes comprised in the receptor binding domain of the SARS-CoV-2 spike protein.

Abstract: Embodiments of the present disclosure disclose a method and an apparatus for processing vehicle-related information based on blockchain, and a computer device and a computer readable storage medium. The method according to an embodiment of the present disclosure includes: a node of a blockchain network may obtain vehicle-related information of a user, embed an identifier of the belonged user into the vehicle-related information of the user, deposit the vehicle-related information embedded with the identifier of the belonged user in a blockchain as a transaction object based on the blockchain network. When the transaction on the vehicle-related information embedded with the identifier of the belonged user is detected, whether the seller of the transaction is the user corresponding to the embedded belonged identifier, if it is not continuation of the transaction is prohibited or restricted.

Abstract: A second-hand vehicle transaction method and server, the method comprises: receiving second-hand vehicle sales information and a sales smart contract submitted by a seller client, registering which in a block chain and perform a entire network radio; receiving a second-hand vehicle transaction request submitted by a buyer client, according to which searching matched second-hand vehicle sales information, and sending the matched second-hand vehicle sales information to the buyer client; executing a target sales smart contract according to a target second-hand vehicle information selected by the buyer client; generating a second-hand vehicle sales contract according to the execution result, and registering the second-hand vehicle sales contract in the block chain after the second-hand vehicle sales contract is confirmed by the buyer client and the seller client.

Abstract: Agents for stimulating activity of methyl modifying enzymes and methods of using the enzymes in assays to identify enzyme modulators are provided herein.