Abstract: Systems, methods, and computer-readable storage media are provided for efficient real-time ink stroke smoothing, trajectory prediction, and GPU-leveraged rendering of ink stroke input. First and second ink points are received and an active Bézier approximation is computed based thereupon. Sequentially later in time that the first and second ink points, a third ink point is received. It is determined whether the third ink point adequately fits the active Bézier approximation. Where it is determined that the third ink point adequately fits, an updated active Bézier approximation is computed that includes the first, second and third ink points. Where it is determined that the third ink point fails to adequately fit, a different new Bézier approximation is computed that includes the third ink point but not the first and second ink points. Leveraging a GPU, a smoothed ink stroke based upon the Bézier approximation(s) is rendered.

Abstract: Aspects of the invention provide virtual hover zones. When a user lowers a hovering stylus while remaining within a hover zone, cursor control is modified to be more easily controllable by the user. If the user pauses the stylus in mid-air before lowering the stylus, and if the stylus remains within the hover zone, then upon touchdown the cursor may be moved to the projection of the location where the stylus was paused. Any action that may be taken in response to the touch down may be sent to the projection location as well. Also provided are cursor control zones. A dampening zone may be used to provide dampened cursor movement feedback in response to movement input provided by a pointing device. Also, a dead zone may be used to prohibit cursor movement in response to movement input provided by the pointing device.

Abstract: Treatment of proliferative diseases with a combination of a b-Raf inhibitor and MDM2 inhibitor.

Abstract: User experience of the performance of a computing device is improved through an operating system that processes inputs from a soft keyboard to provide information that can be used to accurately determine keys a user intended to strike while typing. For each detected tap, the operating system provides a probability that one or more keys were the intended target for the user. These probabilities may be computed from probability distribution functions that are dynamically determined based on user and/or system factors, such as typing rate and keyboard style or layout. Other components may use the probabilities to select a key corresponding to a detected keyboard tap as representing the intended user input. The selection may be made based on the probabilities alone or in combination with contextual factors that yield an overall probability that a detected tap arose from a user targeting a specific key.

Abstract: Treatment of proliferative diseases with a combination of a b-Raf inhibitor and MDM2 inhibitor.

Abstract: The present disclosure relates to a conductive connection structure, and more particularly to a pin structure and pin connection structure thereof. The pin structure is disposed at least one side of an anisotropic conductive film. A plurality of conductive particles is distributed over the interior of the anisotropic conductive film. The pin structure comprises: a plurality of columns which are interspaced, wherein, the conductive particles are in the periphery of the columns. The pin structure and pin connection structure provided by the present disclosure use a pin structure comprising a plurality of columns which are interspaced. When the anisotropic conductive film is used to laminate pin structures, spacing between adjacent columns can contain the conductive particles so as to reduce the number of conductive particle that flow between the left-and-right adjacent pin structures, thereby reducing incidence of short circuit of the left-and-right adjacent pin structures.

Abstract: A transform and inverse transform circuit is provided. The transform and inverse transform circuit includes: at least one quantization and inverse quantization circuit, including at least one quantization and inverse quantization unit, wherein each quantization and inverse quantization unit includes a plurality of first coefficients, and each quantization and inverse quantization unit performs quantization or inverse quantization on one of multiple ways of inputting data; and at least one one-dimensional transform circuit, coupled to the quantization and inverse quantization circuit, wherein the one-dimensional transform circuit includes a plurality of second coefficients, wherein the one-dimensional transform circuit performs one-dimensional transform on the inputting data processed by the quantization and inverse quantization circuit, wherein the plurality of first coefficients and the plurality of second coefficients are set up based on a video codec standard.

Abstract: Techniques for identifying inadvertent user input, such as inadvertent touch contact or air input, are described. The techniques may include classifying a touch contact or air input as intentional or unintentional based on contextual information related to the touch contact, the air input, or a device via which the touch contact or air input was received. In some examples, the contextual information may indicate how a user is interacting with the device, such as a position of the user's hand, a location of the touch contact on a touch surface, a path of user's touch trajectory, an application with which the user may be interacting, keyboard input history of the user, and so on. When the user input is classified as unintentional, the techniques may refrain from performing an action that is generally triggered by the user input.

Abstract: The present invention relates to a combination therapy of propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide, or a pharmaceutically acceptable salt thereof, and an EGFR inhibitor for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer.

Abstract: Aspects of the invention provide virtual hover zones. When a user lowers a hovering stylus while remaining within a hover zone, cursor control is modified to be more easily controllable by the user. If the user pauses the stylus in mid-air before lowering the stylus, and if the stylus remains within the hover zone, then upon touchdown the cursor may be moved to the projection of the location where the stylus was paused. Any action that may be taken in response to the touch down may be sent to the projection location as well. Also provided are cursor control zones. A dampening zone may be used to provide dampened cursor movement feedback in response to movement input provided by a pointing device. Also, a dead zone may be used to prohibit cursor movement in response to movement input provided by the pointing device.

Abstract: Treatment of proliferative diseases with a combination of a b-Raf inhibitor and MDM2 inhibitor.

Abstract: Aspects of the invention provide virtual hover zones. When a user lowers a hovering stylus while remaining within a hover zone, cursor control is modified to be more easily controllable by the user. If the user pauses the stylus in mid-air before lowering the stylus, and if the stylus remains within the hover zone, then upon touchdown the cursor may be moved to the projection of the location where the stylus was paused. Any action that may be taken in response to the touch down may be sent to the projection location as well. Also provided are cursor control zones. A dampening zone may be used to provide dampened cursor movement feedback in response to movement input provided by a pointing device. Also, a dead zone may be used to prohibit cursor movement in response to movement input provided by the pointing device.

Abstract: The invention is concerned with the strains of B. coagulans for lactic acid production and the related methods, in which the carbon sources are pentose or hexose or the agricultural or industrial wastes containing pentose or hexose or a mixture of both. According to the invention, the highest amount of L-lactic acid produced from glucose is 173 g/L, the optical purity is over 99%, the yield is up to 0.98, and the productivity is up to 2.4 g/L per hour. The highest amount of L-lactic acid produced from xylose is 195 g/L, the optical purity is over 99%, the yield is up to 0.98, and the productivity is up to 2.7 g/L per hour. The highest amount of L-lactic acid produced from reducing sugars in xylitol byproducts is 106 g/L, the optical purity is over 99%, and the productivity is up to 2.08 g/L per hour. The B. coagulans strains XZL4 (DSM No. 23183) and XZL9 (DSM No.

Abstract: The invention is concerned with the strains of B. coagulans for lactic acid production and the related methods, in which the carbon sources are pentose or hexose or the agricultural or industrial wastes containing pentose or hexose or a mixture of both. According to the invention, the highest amount of L-lactic acid produced from glucose is 173 g/L, the optical purity is over 99%, the yield is up to 0.98, and the productivity is up to 2.4 g/L per hour. The highest amount of L-lactic acid produced from xylose is 195 g/L, the optical purity is over 99%, the yield is up to 0.98, and the productivity is up to 2.7 g/L per hour. The highest amount of L-lactic acid produced from reducing sugars in xylitol byproducts is 106 g/L, the optical purity is over 99%, and the productivity is up to 2.08 g/L per hour. The B. coagulans strains XZL4 (DSM No. 23183) and XZL9 (DSM No.

Abstract: The present disclosure relates to a conductive connection structure, and more particularly to a pin structure and pin connection structure thereof. The pin structure is disposed at least one side of an anisotropic conductive film. A plurality of conductive particles is distributed over the interior of the anisotropic conductive film. The pin structure comprises: a plurality of columns which are interspaced, wherein, the conductive particles are in the periphery of the columns. The pin structure and pin connection structure provided by the present disclosure use a pin structure comprising a plurality of columns which are interspaced. When the anisotropic conductive film is used to laminate pin structures, spacing between adjacent columns can contain the conductive particles so as to reduce the number of conductive particle that flow between the left-and-right adjacent pin structures, thereby reducing incidence of short circuit of the left-and-right adjacent pin structures.

Abstract: User experience of the performance of a computing device is improved through an operating system that processes inputs from a soft keyboard to provide information that can be used to accurately determine keys a user intended to strike while typing. For each detected tap, the operating system provides a probability that one or more keys were the intended target for the user. These probabilities may be computed from probability distribution functions that are dynamically determined based on user and/or system factors, such as typing rate and keyboard style or layout. Other components may use the probabilities to select a key corresponding to a detected keyboard tap as representing the intended user input. The selection may be made based on the probabilities alone or in combination with contextual factors that yield an overall probability that a detected tap arose from a user targeting a specific key.

Abstract: User inputs can indicate an intent of a user to target a location on a display. In order to determine a targeted point based on a user input, a computing device can receive an indication of at least one point, an indication of a width, and an indication of a height. The computing device can estimate a portion of the display based on the indication of the at least one point, the indication of the width, and the indication of the height. The computing device can also determine the targeted point based on a location of the at least one point and based on a location of a portion of one or more objects within the estimated portion of the display.

Abstract: A user interface in a social networking system enables users to connect to and interact with each other using a third-party communication service, such as a VoIP or video chat service. A user initiates an interaction with another user in the social networking system, which passes the users' information to the third-party communication service provider to allow it to provide the requested service. The social networking system may pass an encrypted identifier for the users so that the third-party communication service does not have access to the real identities of the social networking system's users. A user of the social networking system may use this process to video conference with users of the third-party communication service, rather than just other users of the social networking system, and vice versa.

Abstract: The present invention relates to a combination therapy of propane-1-sulfonic acid{3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl-2,4-difluoro-phenyl]-amide}, or a pharmaceutically acceptable salt thereof, and an interferon for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. In particular, the present invention relates to such a therapy wherein the interferon is peginterferon alfa-2a and the disorder is melanoma containing the V600E b-Raf mutation.

Abstract: The present invention relates to a combination therapy of propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide, or a pharmaceutically acceptable salt thereof, and an EGFR inhibitor for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer.