Patents by Inventor Feihong DONG

Feihong DONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230044120
    Abstract: Disclosed is an ultrasonic blood perfusion imaging method for a single blood vessel, comprising: setting an ultrasound focusing label point in a blood vessel contour of a blood vessel to be measured in a region to be measured; obtaining a preactivated ultrasound image of the region to be measured when an ultrasound contrast agent is in an inactive state; activating the ultrasound contrast agent; obtaining an activated ultrasound image of the region to be measured when the ultrasound contrast agent is in an activated state; obtaining an activation map of the ultrasound contrast agent in the blood vessel to be measured; and obtaining a blood flow perfusion distribution map of the blood vessel to be measured. The ultrasound contrast agent is activated at the ultrasound focusing label point causing liquid-to-gas conversion, and the ultrasound signal changes from dark to bright.
    Type: Application
    Filed: October 21, 2022
    Publication date: February 9, 2023
    Applicant: Nanjing Transcend Vivoscope Bio-Technology Co., LTD
    Inventors: Jian AN, Feihong DONG, Jiabin ZHANG, Jue ZHANG
  • Publication number: 20220296215
    Abstract: A method of delivery of an ultrasound-guided drug-loaded microbubble, an electronic device, and a computer-readable storage medium are provided. The method includes: emitting a first ultrasonic signal by utilizing an array transducer, to break a drug-loaded microbubble in a current breaking region; emitting a second ultrasonic signal by utilizing the array transducer, to obtain an ultrasound image; identifying a contour of a blood vessel of the breaking region based on the ultrasound image; and updating a characteristic parameter of the breaking region based on the contour of the blood vessel. According to the method, the breaking region is updated in real time based on the contour of the blood vessel, so that delivery accuracy of a drug-loaded microbubble is improved, and avoiding unnecessary tissue damage.
    Type: Application
    Filed: June 10, 2022
    Publication date: September 22, 2022
    Applicant: Nanjing Transcend Vivoscope Bio-Technology Co., LTD
    Inventors: Wenyu GUO, Jian AN, Feihong DONG, Shuo HUANG, Jue ZHANG
  • Publication number: 20220280660
    Abstract: Disclosed are a composition for ultrasound contrast agent, an ultrasound contrast agent, and a preparation method thereof. The composition for ultrasound contrast agent includes a lipid, a stabilizer and an acoustic-induced deformation material; relative to 100 parts by weight of the lipid, the content of the stabilizer is 20 to 100 parts by weight, and the content of the acoustic-induced deformation material is 1 to 15 parts by weight; and the acoustic-induced deformation material is deformed under a specific acoustic wave, and the characteristic response frequency of the acoustic-induced deformation material is 0.01 MHz to 50 MHz. The microbubble ultrasound contrast agent has better stability, thereby it circulates in vivo for a longer time, and has lower mechanical index, so that the inertial cavitation occurs under a low-energy ultrasonic wave.
    Type: Application
    Filed: May 24, 2022
    Publication date: September 8, 2022
    Applicant: Nanjing Transcend Vivoscope Bio-Technology Co., LTD
    Inventors: Wenyu GUO, Shuo HUANG, Feihong DONG, Jue ZHANG
  • Publication number: 20220265869
    Abstract: Disclosed are a composition for magnetic ultrasound contrast agent, a magnetic ultrasound contrast agent, a magnetic microbubble ultrasound contrast agent, and a preparation method thereof. The composition for magnetic ultrasound contrast agent includes a lipid, a surfactant and a magnetic nanoparticle; the surfactant consists of a surfactant A and a surfactant B, the surfactant A is in a free state, and the surfactant B is in a bonding state and is modified on the surface of the magnetic nanoparticle; the HLB value of the surfactant A is greater than 8. The magnetic microbubble ultrasound contrast agent obtained from the composition for magnetic ultrasound contrast agent has higher stability and may meet requirements for in vivo cyclic targeted delivery, thereby achieving the local high-concentration targeted delivery of a medication.
    Type: Application
    Filed: May 11, 2022
    Publication date: August 25, 2022
    Applicant: Nanjing Transcend Vivoscope Bio-Technology Co., LTD
    Inventors: Shuo HUANG, Wenyu GUO, Feihong DONG, Jue ZHANG
  • Publication number: 20220257804
    Abstract: Disclosed are a film-forming agent composition for contrast agent, a film-forming lipid solution including the film-forming agent composition, a contrast agent including the film-forming lipid solution, and a preparation method thereof. The film-forming agent composition for contrast agent includes a lipid, an emulsifier and a surface charge modifier; relative to 100 parts by weight of the lipid, the content of the emulsifier is 20-50 parts by weight, and the content of the surface charge modifier is 10-35 parts by weight; and the lipid is a carboxylated phospholipid, and the surface charge modifier is a polyelectrolyte. Based on the composition, the nanodroplets of the resulting contrast agent have more uniform particle size, higher stability and better controllability, as well as a lower threshold value for ultrasonic gasification.
    Type: Application
    Filed: May 4, 2022
    Publication date: August 18, 2022
    Applicant: Nanjing Transcend Vivoscope Bio-Technology Co., LTD
    Inventors: Feihong DONG, Jian AN, Jiabin ZHANG, Wenyu GUO, Jue ZHANG
  • Publication number: 20160006613
    Abstract: According to an example, a Virtual Switch Instance (VSI) in a provider edge (PE) device is obtained and an encapsulation Virtual Local Area Network (VLAN) ID corresponding to the VSI is obtained. A service VLAN (SVLAN) ID in VLAN mapping information in a customer edge (CE) device adjacent to the PE device in the VSI is also obtained, and the CE device is determined to be an access CE device of the PE device in the VSI in response to a determination that the SVLAN ID is identical to the encapsulation VLAN ID.
    Type: Application
    Filed: December 2, 2013
    Publication date: January 7, 2016
    Inventors: Feihong DONG, Xiang SHI, Xiaodong LI