Patents by Inventor Feipu YANG

Feipu YANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220227773
    Abstract: The present invention relates to a fused ring compound represented by general formula (I), a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition and use thereof. The compound provided in the present invention is useful for treating, preventing and/or controlling various nervous system disorders. The compound provided in the present invention modulates one or more monoamine transporters, inhibits the reuptake of endogenous monoamines such as dopamine, 5-hydroxytryptamine, and norepinephrine (e.g., from the synaptic cleft), and/or modulates the 5-HT3 receptor.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 21, 2022
    Inventors: Jingshan SHEN, Yang HE, Chunhui WU, Feipu YANG, Zhen WANG, Junchi ZHANG, Fuqiang ZHU, Hongjian QIN
  • Maleate salt of benzothiophene compound, crystalline form thereof, and use thereof
    Patent number: 11384073
    Abstract: The present disclosure relates to a maleate salt of a benzothiophene compound, a crystalline form thereof, and a use thereof. Specifically, the present disclosure relates to a compound represented by formula (I-A), a crystalline form A thereof, a preparation method of a pharmaceutical composition including the same, and a use of the pharmaceutical composition in the preparation of drugs for preventing or treating diseases of the central nervous system. The compound represented by formula (I-A) and the crystalline form A thereof in the present disclosure have excellent physical and chemical properties, high oral bioavailability, excellent drugability, and are well-suited for pharmaceutical preparation, application, and preservation.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: July 12, 2022
    Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANGHAI CO., LTD.
    Inventors: Jingshan Shen, Yang He, Zhen Wang, Jianfeng Li, Yongjian Liu, Jin Suo, Guanghui Tian, Weiming Chen, Feipu Yang, Yu Wang, Xiangrui Jiang, Rongxia Zhang, Hualiang Jiang
  • MALEATE SALT OF BENZOTHIOPHENE COMPOUND, CRYSTALLINE FORM THEREOF, AND USE THEREOF
    Publication number: 20210309648
    Abstract: The present disclosure relates to a maleate salt of a benzothiophene compound, a crystalline form thereof, and a use thereof. Specifically, the present disclosure relates to a compound represented by formula (I-A), a crystalline form A thereof, a preparation method of a pharmaceutical composition including the same, and a use of the pharmaceutical composition in the preparation of drugs for preventing or treating diseases of the central nervous system. The compound represented by formula (I-A) and the crystalline form A thereof in the present disclosure have excellent physical and chemical properties, high oral bioavailability, excellent drugability, and are well-suited for pharmaceutical preparation, application, and preservation.
    Type: Application
    Filed: December 18, 2020
    Publication date: October 7, 2021
    Inventors: Jingshan Shen, Yang He, Zhen Wang, Jianfeng Li, Yongjian Liu, Jin Suo, Guanghui Tian, Weiming Chen, Feipu Yang, Yu Wang, Xiangrui Jiang, Rongxia Zhang, Hualiang Jiang
  • Heterocyclic compounds, process for preparation of the same and use thereof
    Patent number: 10174011
    Abstract: The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: January 8, 2019
    Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANDONG CO., LTD.
    Inventors: Hualiang Jiang, Zhen Wang, Jianfeng Li, Rongxia Zhang, Yang He, Yongjian Liu, Minghao Bi, Zheng Liu, Guanghui Tian, Weiming Chen, Feipu Yang, Chunhui Wu, Yu Wang, Xiangrui Jiang, Jingjing Yin, Guan Wang, Jingshan Shen
  • HETEROCYCLIC COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF
    Publication number: 20170158680
    Abstract: The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.
    Type: Application
    Filed: March 9, 2015
    Publication date: June 8, 2017
    Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANDONG CO., LTD.
    Inventors: Hualiang JIANG, Zhen WANG, Jianfeng LI, Rongxia ZHANG, Yang HE, Yongjian LIU, Minghao BI, Zheng LIU, Guanghui TIAN, Weiming CHEN, Feipu YANG, Chunhui WU, Yu WANG, Xiangrui JIANG, Jingjing YIN, Guan WANG, Jingshan SHEN