Patents by Inventor Felipe MATSUNAGA

Felipe MATSUNAGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Opioid detection based on high quality graphene transistor arrays and a synthetic mu receptor
    Patent number: 10809222
    Abstract: The present invention provides methods for fabricating field-effect devices and sensor arrays. The field of the invention also pertains to methods of using the sensors individually, in combination, and in array fashion to detect molecules. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: October 20, 2020
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Alan T. Johnson, Jin Xi, Ganghee Han, Mitchell Lerner, Jeffery G. Saven, Renyu Liu, Felipe Matsunaga, Jose Manuel Perez-Aguilar
  • Water soluble G-protein coupled receptor
    Patent number: 9670264
    Abstract: Described herein are recombinant integral membrane proteins having multiple transmembrane domains that have been engineered to be less hydrophobic, through alteration of the amino acid sequence of the native protein, but retain the ability to bind their natural ligand. The decreased hydrophobicity of the described proteins makes them more water soluble than the native protein, which allows the described proteins to be expressed in bacteria in large quantities and isolated in the absence of membranes, all while retaining the ability to interact with known ligands.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: June 6, 2017
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Renyu Liu, Jeffery G Saven, Jose Manuel Perez-Aguilar, Felipe Matsunaga, Jin Xi
  • OPIOID DETECTION BASED ON HIGH QUALITY GRAPHENE TRANSISTOR ARRAYS AND A SYNTHETIC MU RECEPTOR
    Publication number: 20160123919
    Abstract: The present invention provides methods for fabricating field-effect devices and sensor arrays. The field of the invention also pertains to methods of using the sensors individually, in combination, and in array fashion to detect molecules. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.
    Type: Application
    Filed: April 25, 2014
    Publication date: May 5, 2016
    Applicant: The Trustees of The University of Pennsylvania
    Inventors: Alan T. JOHNSON, Jin XI, Ganghee HAN, Mitchell LERNER, Jeffery G. SAVEN, Renyu LIU, Felipe MATSUNAGA, Jose Manuel PEREZ-AGUILAR
  • WATER SOLUBLE G-PROTEIN COUPLED RECEPTOR
    Publication number: 20160102130
    Abstract: Described herein are recombinant integral membrane proteins having multiple transmembrane domains that have been engineered to be less hydrophobic, through alteration of the amino acid sequence of the native protein, but retain the ability to bind their natural ligand. The decreased hydrophobicity of the described proteins makes them more water soluble than the native protein, which allows the described proteins to be expressed in bacteria in large quantities and isolated in the absence of membranes, all while retaining the ability to interact with known ligands.
    Type: Application
    Filed: April 25, 2014
    Publication date: April 14, 2016
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Renyu LIU, Jeffery G. SAVEN, Jose Manuel PEREZ-AGUILAR, Felipe MATSUNAGA, Jin XI