Abstract: Systems and methods may be provided for wirelessly monitoring physiological vital signs. The systems and methods may include transmitting, from a local replication system via a wireless communications link, one or more stimulus signals to a remote signal acquisition subsystem that may be in communication with at least one remote sensor, where, responsive to the one or more stimulus signals, the at least one remote sensor is operable to generate one or more interrogation signals applied to a physiological system under test, where the at least one remote sensor may detect one or more response signal, where the one or more response signals may include a detected physiological system response to the one or more interrogation signals.