Abstract: An anchoring system and method includes a guide rail having a rail body that includes a track that has a different width at a first end of the rail body than at a second end of the rail body. An applicator assembly includes a linkage system and an anchor system. The linkage system includes rollers that are disposed within the track of the guide rail. The applicator assembly moves in a first direction based on movement of the rollers within the track. The linkage system includes an extension component having a contoured surface that engages a first side of a rail. The anchor system moves in a first direction of rotation toward a second side of the rail and the extension component moves in a second direction of rotation toward the first side of the rail during an application operation.

Abstract: A gas hydrate inhibitor composition is disclosed including two main components: (1) 5-95% of an amphiphilic compound with a hydrophobic tail linked to a hydrophilic head group through various linking structures, and (2) 5-95% of a cationic surfactant based on di(C8-C18 alkyl)dimethyl ammonium salts. The linking structures include amide-based linkers and more complex structures containing hydroxyl groups, carboxylic acid groups, and various combinations. The composition features specific requirements for substituent groups ranging from small alkyl chains to larger hydrocarbyl groups.

Abstract: The present invention provides an antigen binding protein specifically binding to a CT45 antigenic peptide that is in a complex with a major histocompatibility complex (MHC) protein, wherein the CT45 antigenic peptide comprises or consists of the amino acid sequence of SEQ ID NO: 138 (KIFEMLEGV) and wherein the antigen binding protein comprises a first polypeptide comprising a variable domain VA comprising complementarity determining regions CDRa1, CDRa2 and CDRa3 and a second polypeptide comprising a variable domain VB comprising CDRb1, CDRb2 and CDRb3. Also provided are nucleic acids encoding the antigen binding proteins, vectors comprising the nucleic acids, recombinant cells expressing the antigen binding proteins and pharmaceutical compositions comprising the antigen binding proteins. The invention further provides the antigen binding proteins for use in medicine and a method of producing the antigen binding protein.

Abstract: A cartridge configured for use with an aerosol-generating device is provided, including a power supply, control circuitry, a detector including a light source and light sensor, and a cavity configured to receive the cartridge, the cartridge including: a container; an electrically operated heater; an aerosol forming chamber; and a taggant having an identifiable spectroscopic signature that the detector of the aerosol-generating device can use to distinguish the aerosol-generating article from other articles.

Abstract: Disclosed herein is a process for making an electrode active material. The process includes the following steps: (a) providing an (oxy)hydroxide of TM, where TM is a transition metal and includes nickel and, optionally, at least one of cobalt and manganese, (b) mixing the (oxy)hydroxide of TM with 75 to 85 mol-% of a lithium source, referring to TM, and at least one compound of Mg or Al, (c) treating the resultant mixture at a temperature in the range of from 400 to 700° C., thereby obtaining a powder, (d) mixing the powder from step (c) with a source of lithium and with at least one compound of Mg or Al and with at least one compound of Nb, Ta, W, Ti or Zr, and (e) treating the mixture obtained from step (d) thermally at a temperature in the range of from 550 to 800° C.

Abstract: The present invention relates to CNP prodrugs in which the carrier is covalently and reversibly attached to the ring moiety of a CNP moiety, to pharmaceutical compositions comprising such CNP prodrugs, to their uses and to methods of treating diseases that can be treated with the CNP prodrugs of the present invention.

Abstract: A rear loading device for a bicycle is disclosed with a central structure portion configured to be secured to a bicycle frame rearwardly of its crankset, a left-side structure portion and a right-side structure portion pivotally connected to the central structure portion, and a mechanism including at least one joint connecting the left-side structure portion and the right-side structure portion to the central structure portion or to the frame of the bicycle, the mechanism enabling displacement of the left-side structure portion and the right-side structure portion relative to one another between a deployed configuration in which top ends of the left-side structure portion and the right-side structure portion are distanced to define a cargo volume therebetween, and a retracted configuration in which the top ends of the left-side structure portion and the right-side structure portion are adjacent to one another to reduce the cargo volume.

Abstract: A method for cleaning a molding insert for injection-molding of single-use ophthalmic lens molds comprises the steps of providing an insert holder and a molding surface of the molding insert faces away from the insert holder. A dry ice nozzle comprises an inlet for the supply of dry ice, a nozzle channel comprising a longitudinally extending diverging inner wall portion terminating in an outlet opening of the nozzle channel, and a nozzle housing with a circumferentially running distal end wall. The nozzle housing further comprises a housing wall portion extending away from the distal end wall to define an exhaust channel. The method further comprises positioning the dry ice nozzle on the insert holder, supplying dry ice particles to the nozzle inlet to generate a jet of dry ice particles impinging on the molding surface of the molding insert, and removing exhaust gases.

Abstract: Lumbar lordosis facilitator device composed of one or several fluid bags (1). Each bag (1) has one or several fluid entry points (2) connected to a pressurized fluid source (7) so that they allow the filling of the bag or bags (1) from a primary end to one or several fluid exit points (3) located in a way that allow the evacuation of the fluid to a secondary end on the opposite side of the primary end. The device also has a fluid inner pressure regulating system that can employ several sensor systems (8,9,10).

Abstract: A battery system, in particular for a vehicle, includes a battery system housing, wherein the battery system housing has an air inlet region and an air outlet region for the air flowing through the battery system housing and at least one battery unit. The at least one battery unit is accommodated in the battery system housing so that air flowing through the battery system housing can flow around the at least one battery unit.

Abstract: Articulating surgical instruments are disclosed. In one embodiment, a surgical instrument may include an elongated shaft assembly including an articulable portion moveable between a non-articulated configuration and an articulated configuration. First and second articulating shafts of the elongated shaft assembly may be coaxially arranged and axially fixed at an attachment point located distally from the articulable portion. Proximal portions of the first and second articulating shafts may be displaceable in opposing directions to articulate the articulable portion from the non-articulated configuration to the articulated configuration. In another embodiment, an articulation control may be movable from a first position to a second position to move an articulation lock from a locked configuration to an unlocked configuration to selectively permit articulation of a surgical instrument. The articulation lock also may be movable from the second position to a third position to articulate the surgical instrument.

Abstract: A method of securely deploying a software package comprises storing validity data describing restricted use of a restricted use token; receiving a command including a URL to deploy a software package; testing validity of the URL based on the validity data; and downloading, when the testing is successful, the software package via a secure channel, wherein the method is performed using one or more processors.

Abstract: Disclosed is a support structure for a cryogenic system with a first compartment, a second compartment, and a third compartment that are vertically stacked in this order; the first compartment configured to accommodate a cryostat; the second compartment configured to provide access to a top portion of the cryostat for performing measurements and/or tests on an object inside the cryostat; the third compartment configured to accommodate electronics for controlling at least the cryostat.

Abstract: A method for identifying a motor vehicle, in particular AVP motor vehicle. The method includes: agreeing on a common secret by an infrastructure-side system, in particular AVP system, of an infrastructure, in particular of a parking lot, with a motor-vehicle-side system, in particular AVP system, of the motor vehicle; ascertaining a first code on the basis of the common secret using a predetermined ascertainment rule by means of the infrastructure-side system; detecting a signal which was emitted from a motor vehicle located within the infrastructure and transmits a second code, by means of the infrastructure-side system; comparing the second code to the first code by means of the infrastructure-side system in order to identify the motor vehicle emitting the signal as the one motor vehicle with the motor-vehicle-side system of which the common secret has been agreed.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A cargo floor, in particular a trunk or storage floor, for a motor vehicle. The cargo floor includes a layer-shaped construction with a core layer, a first reinforcement layer and a second reinforcement layer. The core layer is arranged between the first reinforcement layer and the second reinforcement layer and includes a honeycomb structure produced in particular from polypropylene (PP). It is conceivable that the first reinforcement layer and/or the second reinforcement layer each include a meshwork made of a plurality of thermoplastic continuous fiber tapes (UD tapes).

Abstract: A device for service-oriented communication with a signal-based hardware architecture. The device comprises a number of service-oriented communication interfaces for communicative connection to a number of external service-oriented communication partners, a number of signal-based communication interfaces for communication with a number of external signal-based devices, and an embedded system.

Abstract: A trajectory is determined for inserting a patient into an MR scanner. An avatar representing specific body dimensions is provided. The avatar includes location information relating to an implant. A spatial magnetic field gradient data set relating to the scanner is provided. An avatar pose at a starting point of the trajectory is defined, and a course for the trajectory is provided. For several points on the trajectory, the corresponding magnetic field value are determined by combining the spatial magnetic field gradient data set with the avatar pose. The trajectory and/or the avatar pose are determined so that the at least one implant only passes regions within the MR scanner that are below a predetermined threshold value concerning the magnetic field gradient.

Abstract: A method for implementing a software update for a selected enclave of a computing system includes obtaining, by a security monitor (SM) of the computing system, the software update for the selected enclave, installing, by the SM, the software update for the selected enclave to provide updated enclave software code, and measuring, by the SM, the updated enclave software code to provide a software update measurement. The updated enclave software code is stored in a memory region isolated from a memory region in which data for the selected enclave is stored. The method further includes transmitting, by the SM, the software update measurement to one or more respective other enclaves that share a memory region with the selected enclave.