Patents by Inventor Felix Heise

Felix Heise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable, Benzyl Alcohol-free Aqueous Solution Formulations Containing Alpha-type Interferon
    Publication number: 20170360891
    Abstract: The present invention provides a stable, isotonic, aqueous solution formulation comprising: (i) 0.1-0.5 mg/mL alpha-type interferon, preferably pegylated alpha-type interferon; (ii) 20 mM Acetate buffer system to maintain a pH of 6.0±0.5; (iii) 5-20 mM L-methionine; (iv) 120-150 mM sodium chloride; (v) 0.01-0.07 percent by weight of a surfactant effective to stabilize the alpha-type interferon, preferably pegylated alpha-type interferon against loss of its activity and (vi) an amount of water for injection sufficient to prepare a solution of the above-listed ingredients.
    Type: Application
    Filed: March 23, 2017
    Publication date: December 21, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Ulla Grauschopf, Michael Adler, Hanns-Christian Mahler, Felix Heise, Susanne Baroth