Patents by Inventor Felix Romain

Felix Romain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gram positive bacteria preparations for the treatment of diseases comprising an immune dysregulation
    Patent number: 8404250
    Abstract: This application relates to compositions comprising components prepared from Gram positive bacteria such as Gram positive facultative intracellular bacteria for treatment of disorders comprising an immune dysregulation in humans and animals.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: March 26, 2013
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Marie-Anne Nahori, Micheline Lagranderie, Gilles Marchal, Bernardo Boris Vargaftig, Jean Lefort, Felix Romain, Georges Hekimian, Philippe Peltre
  • Gram positive bacteria preparations for the treatment of disease comprising an immune dysregulation
    Patent number: 7871627
    Abstract: Compositions comprising components prepared from Gram positive bacteria such as Gram positive facultative intra-cellular bacteria, for example mycobacteria, including extended freeze-dried killed Gram positive bacteria, their method of preparation and their use in humans and animals, for the prevention and/or the treatment of disorders comprising an immune dysregulation such as cancer, autoimmune diseases, allergy and tuberculosis.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: January 18, 2011
    Assignees: Institut Pasteur, Institut National de la Sante Et de la Recherche Medicale (INSERM)
    Inventors: Marie-Anne Nahori, Micheline Lagranderie, Gilles Marchal, Bernardo Boris Vargaftig, Jean Lefort, Felix Romain, Georges Hekimian, Philippe Peltre
  • GRAM POSITIVE BACTERIA PREPARATIONS FOR THE TREATMENT OF DISEASES COMPRISING AN IMMUNE DYSREGULATION
    Publication number: 20100272756
    Abstract: This application relates to compositions comprising components prepared from Gram positive bacteria such as Gram positive facultative intracellular bacteria for treatment of disorders comprising an immune dysregulation in humans and animals.
    Type: Application
    Filed: October 21, 2009
    Publication date: October 28, 2010
    Applicants: INSTITUT PASTEUR, INSTITUT NAT DE LA SANTE ET DE LA RECHERCHE MED
    Inventors: Marie-Anne NAHORI, Micheline Lagranderie, Gilles Marchal, Bernardo Boris Vargaftig, Jean Lefort, Félix Romain, Georges Hekimian, Philippe Peltre
  • Immunogenic glycopeptides, screening, preparation and uses
    Patent number: 7820142
    Abstract: The invention relates to immunogenic glycopeptides derived from pathogenic microorganisms, which can be used for immunization and diagnosing infections dye to such pathogenic microorganisms and also to method for the selection and preparation thereof.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: October 26, 2010
    Assignee: Institut Pasteur
    Inventors: Gilles Marchal, Félix Romain, Pascale Pescher, Françoise Baleux, Daniel Scott-Algara, Laurence Mulard
  • Immunogenic glycopeptides, screening, preparation and uses
    Patent number: 7658929
    Abstract: The invention concerns immunogenic glycopeptides derived from pathogenic microorganisms, useful for vaccination and diagnosis of infections caused by said pathogenic microorganisms (bacteria or fungi), and methods for selecting them and preparing them.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: February 9, 2010
    Assignee: Institut Pasteur
    Inventors: Gilles Marchal, Felix Romain, Pascale Pescher
  • Immunogenic Glycopeptides for Diagnosing Pathogenic Microorganisms Infections
    Publication number: 20080293620
    Abstract: A method for diagnosing an infection in a patient likely to be infected with a pathogenic microorganism, comprising the detection of CD4+ T lymphocytes recognizing at least one glycopeptide derived from said pathogenic microorganism, essentially consisting of a glycosylated T epitope, comprising from 14 to 25 amino acids, among which at least one neutral amino acid is bonded to a disaccharide or to a trisaccharide, and at least 15% of said amino acids are prolines, one of the prolines being located in position ?1 to ?4, relative to the position of said neutral amino acid.
    Type: Application
    Filed: September 29, 2005
    Publication date: November 27, 2008
    Applicant: Institut Pasteur
    Inventors: Gilles Marchal, Felix Romain, Pascale Pescher, Francoise Baleux, Daniel Scott-Algara, Laurence Mulard
  • IMMUNOGENIC GLYCOPEPTIDES, SCREENING, PREPARATION AND USES
    Publication number: 20080233599
    Abstract: The invention concerns immunogenic glycopeptides derived from pathogenic microorganisms, useful for vaccination and diagnosis of infections caused by said pathogenic microorganisms (bacteria or fungi), and methods for selecting them and preparing them.
    Type: Application
    Filed: February 21, 2008
    Publication date: September 25, 2008
    Applicant: INSTITUT PASTEUR
    Inventors: Gilles Marchal, Felix Romain, Pascale Pescher
  • Immunogenic glycopeptides, screening, preparation and uses
    Patent number: 7361348
    Abstract: The invention concerns immunogenic glycopeptides derived from pathogenic microorganisms, useful for vaccination and diagnosis of infections caused by said pathogenic microorganisms (bacteria or fungi), and methods for selecting them and preparing them.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: April 22, 2008
    Assignee: Institut Pasteur
    Inventors: Gilles Marchal, Felix Romain, Pascale Pescher
  • Gram positive bacteria preparations for the treatment of disease comprising an immune dysregulation
    Publication number: 20070190076
    Abstract: Compositions comprising components prepared from Gram positive bacteria such as Gram positive facultative intra-cellular bacteria, for example mycobacteria, including extended freeze-dried killed Gram positive bacteria, their method of preparation and their use in humans and animals, for the prevention and/or the treatment of disorders comprising an immune dysregulation such as cancer, autoimmune diseases, allergy and tuberculosis.
    Type: Application
    Filed: November 17, 2006
    Publication date: August 16, 2007
    Inventors: Marie-Anne Nahori, Micheline Lagranderie, Gilles Marchal, Bernado Vargaftig, Jean Lefort, Felix Romain, Georges Hekimian, Philippe Peltre
  • Mycobacterial proteins, microorganisms producing them and their use for vaccines and the detection of tuberculosis
    Patent number: 7101555
    Abstract: Mycobacterium tuberculosis protein having a molecular weight of 28 779 Da, and hybrid proteins containing at least portions of its sequence. These proteins may in particular be used in vaccines or for the detection of specific tuberculosis antibodies.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: September 5, 2006
    Assignee: Institut Pasteur
    Inventors: Anne Laqueyrerie, Gilles Marchal, Pascale Pescher, Felix Romain
  • Immunogenic glycopeptides, screening, preparation and uses
    Publication number: 20060067888
    Abstract: The invention relates to immunogenic glycopeptides derived from pathogenic microorganisms, which can be used for immunization and diagnosing infections dye to such pathogenic microorganisms and also to method for the selection and preparation thereof.
    Type: Application
    Filed: September 30, 2004
    Publication date: March 30, 2006
    Applicant: INSTITUT PASTEUR
    Inventors: Gilles Marchal, Felix Romain, Pascale Pescher, Francoise Baleux, Daniel Scott-Algara, Laurence Mulard
  • Gram positive bacteria preparations for the treatment of diseases comprising an immune dysregulation
    Publication number: 20060062807
    Abstract: Compositions comprising components prepared from Gram positive bacteria such as Gram positive facultative intra-cellular bacteria, for example mycobacteria, including extended freeze-dried killed Gram positive bacteria, their method of preparation and their use in humans and animals, for the prevention and/or the treatment of disorders comprising an immune dysregulation such as cancer, autoimmune diseases, allergy and tuberculosis.
    Type: Application
    Filed: December 11, 2002
    Publication date: March 23, 2006
    Inventors: Marie-Anne Nahori, Micheline Lagranderie, Gilles Marchal, Bernado Vargaftig, Jean Lefort, Felix Romain, Georges Hekimian, Philippe Peltre
  • Immunogenic glycopeptides, screening, preparation and uses
    Publication number: 20040171523
    Abstract: The invention concerns immunogenic glycopeptides derived from pathogenic microorganisms, useful for vaccination and diagnosis of infections caused by said pathogenic microorganisms (bacteria or fungi), and methods for selecting them and preparing them.
    Type: Application
    Filed: June 20, 2003
    Publication date: September 2, 2004
    Inventors: Gilles Marchal, Felix Romain, Pascale Pescher
  • Mycobacterial proteins, microorganisms producing them and their use for vaccines and for the detection of tuberculosis
    Publication number: 20040142453
    Abstract: Mycobacterium tuberculosis protein having a molecular weight of 28 779 Da, and hybrid proteins containing at least portions of its sequence.
    Type: Application
    Filed: November 25, 2003
    Publication date: July 22, 2004
    Applicant: INSTITUT PASTEUR
    Inventors: Anne Laqueyrerie, Gilles Marchal, Pascale Pescher, Felix Romain
  • Mycobacterial proteins, microorganisms producing them and their use for vaccines and for the detection of tuberculosis
    Patent number: 6676945
    Abstract: Mycobacterium tuberculosis protein having a molecular weight of 28.779 Da, and hybrid proteins containing at least portions of its sequence. These proteins may in particular be used in vaccines or for the detection of specific tuberculosis antibodies.
    Type: Grant
    Filed: November 2, 2001
    Date of Patent: January 13, 2004
    Assignee: Institut Pasteur
    Inventors: Anne Laqueyrerie, Gilles Marchal, Pascale Pescher, Felix Romain
  • Mycobacterial proteins, microorganisms producing them and their use for vaccines and for the detection of tuberculosis
    Publication number: 20030054008
    Abstract: Mycobacterium tuberculosis protein having a molecular weight of 28,799 Da, and hybrid protein containing at least portions of its sequence.
    Type: Application
    Filed: November 2, 2001
    Publication date: March 20, 2003
    Applicant: INSTITUT PASTEUR
    Inventors: Anne Laqueyrerie, Gilles Marchal, Pascale Pescher, Felix Romain
  • Mycrobacterial proteins, microorganisms producing same and uses of said proteins in vaccines and for detecting tuberculosis
    Patent number: 6379902
    Abstract: Mycobacterium tuberculosis protein having a molecular weight of 28 779 Da, and hybrid proteins containing at least portions of its sequence. These proteins may in particular be used in vaccines or for the detection of specific tuberculosis antibodies.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: April 30, 2002
    Assignee: Institut Pasteur
    Inventors: Anne Laqueyrerie, Gilles Marchal, Pascale Pescher, Felix Romain
  • Mycobacterial proteins, microorganisms producing them and their use for vaccines and for the detection of tuberculosis
    Patent number: 6335181
    Abstract: Mycobacterium tuberculosis protein having a molecular weight of 28.779 Da, and hybrid proteins containing at least portions of its sequence. These proteins may in particular be used in vaccines or for the detection of specific tuberculosis antibodies.
    Type: Grant
    Filed: June 21, 2000
    Date of Patent: January 1, 2002
    Assignee: Institut Pasteur
    Inventors: Anne Laqueyrerie, Gilles Marchal, Pascale Pescher, Felix Romain
  • Antibodies Which Bind Mycobacterial Tuberculosis Proteins
    Patent number: 6221353
    Abstract: Antibodies that bind Mycobacterium tuberculosis 28 kDa proteins and immune complexes between the antibodies and proteins.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: April 24, 2001
    Assignee: Institut Pastuer
    Inventors: Anne Laqueyrerie, Gilles Marchal, Pascale Pescher, Felix Romain
  • Mycobacterium proteins and applications
    Patent number: 6060259
    Abstract: Mycobacterium proteins, in particular those of M. bovis, having molecular weights between approximately 44.5 and 47.5 kD. These proteins can have molecular weights of approximately 45 kD or 47 kD and isoelectric pH of approximately 3.7 (45 and 47 kD proteins) and 3.9 (47 kD proteins).These proteins or hybrid proteins containing a part of their sequences can be used as vaccines or as drugs, or for the detection and monitoring of tuberculosis in particular in man and in cattle.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: May 9, 2000
    Assignee: Institut Pasteur
    Inventors: Gilles Marchal, Felix Romain, Pascale Pescher, Cynthia Horn