Abstract: The present disclosure relates generally to biomarkers of activity and/or therapeutic efficacy of anti-CD33 antibodies for the treatment of a disease or injury in an individual, as well as methods related thereto.

Abstract: A method reconfigures an IoT device which is connectable to a cloud backend. The method includes: storing an access code that is input locally in the cloud backend and storing the access code or check information formed on the basis thereof on the IoT device. The method further includes reconfiguring the IoT device, requesting the access code from the cloud backend, inputting the requested access code on a local configuration interface of the IoT device or on an input device connected to the local configuration interface of the IoT device, and comparing the input access code against the access code stored on the IoT device, or the check information formed on the basis thereof. The IoT device is enabled for reconfiguration upon a positive comparison of the input access code against the access code stored, or the check information formed on the basis thereof.

Abstract: Video rendering, including: tracking spatial coordinates of at least one camera during a video sequence forming a shot having multiple frames, wherein each of the at least one camera has a lens; creating a lens profile storing lens data corresponding to the lens of the at least one camera during the shot; encoding the lens data; sending the lens data to a render engine; retracing the movement of the at least one camera during the shot; recreating the lens and one or more characteristics of the lens during the shot; and replicating the shot in a virtual environment using the retraced camera movement and recreated lens characteristics.

Abstract: A respiratory mask system includes a mask interface and a headgear assembly. The headgear assembly is adjustable and comprised of an elastic portion, a non-elastic portion and a restriction mechanism configured to provide a force resisting movement of the non-elastic portion when the elastic portion is extended. There is a support beam coupled to the non-elastic portion and extending along a portion of the headgear that is curved along its longitudinal extent. In this way particular seal modules can be comfortably fitted to a user and any blow off force is mitigated. A particular example of the respiratory mask system includes provision for removable attachment between the seal and a mask frame, the mask frame and a yoke of the headgear; and between a conduit and the mask frame.

Abstract: A posture and movement training garment 100 comprises at least one elastic element arranged to be stretched upon movement of the wearer's trunk and/or at least one of the wearer's limbs away from a predetermined rest or neutral position, thereby to provide the wearer with gentle elastic recoil sufficient to provide the wearer with additional kinaesthetic and/or touch feedback resulting from the movement, substantially without inhibiting the movement. A complementary sports training or physiotherapy garment comprises a fabric base and pockets for the reception of weights, the garment further comprising strips of relatively inextensible material forming a network interconnecting the base material within the pockets, in which the majority of the strips run generally longitudinally of the wearer's limbs and torso and form a branched network with bases mainly originating at the wearer's shoulders and/or hips; and wherein the network does not completely encircle the wearer's limbs and torso.

Abstract: A semiconductor device includes a substrate having a P-well region, an N-well region disposed on either side of and abutting the P-well region, and a deep N-well region disposed beneath and abutting both the P-well region and at least part of the N-well region on either side of the P-well region. The semiconductor device further includes a first conductive layer formed over a cathode region of the P-well region, where a Schottky barrier is formed at a junction of the first conductive layer and the P-well region. The semiconductor device further includes a second conductive layer formed over anode regions of the P-well region, where the anode regions are disposed on either side of the cathode region.

Abstract: A handle for a cleaning device, including a knob which is rotatably arranged at one end of the handle, wherein the knob includes a first knob element and a second knob element. The first knob element is connected to the second knob element, and the second knob element has a recess in which the handle is rotatably arranged. The first knob element is equipped with a latch, by which the first knob element is rotatably locked to the handle. The second knob element has a locking element, and the locking element locks the latch of the first knob element relative to the handle when the first knob element and the second knob element are connected to one another.

Abstract: A midsole for an article of footwear including a three-dimensional mesh including interconnected unit cells and methods of making the same. The interconnected unit cells each include a plurality of struts defining a three-dimensional shape. The interconnected unit cells are connected at nodes having a valence number defined by the number of struts connected at that node. The valence number of the nodes may vary to provide customized characteristics to zones or portions of the midsole. The plurality of interconnected unit cells may be organized in a warped cubic lattice structure. The warped cubic lattice structure and the size/shape of interconnected unit cells may vary to provide customized characteristics to zones or portions of the midsole. The three-dimensional mesh may be customized based on a biometric data profile for an individual, or group of individuals. The midsole may be manufactured using an additive manufacturing process.

Abstract: Vehicle platforms, and systems, subsystems, and components thereof are described. A self-contained vehicle platform or chassis incorporating substantially all of the functional systems, subsystems and components (e.g., mechanical, electrical, structural, etc.) necessary for an operative vehicle. Functional components may include at least energy storage/conversion, propulsion, suspension and wheels, steering, crash protection, and braking systems. Functional components are standardized such that vehicle platforms may be interconnected with a variety of vehicle body designs (also referred to in the art as “top hats”) with minimal or no modification to the functional linkages (e.g., mechanical, structural, electrical, etc.) therebetween. Configurations of functional components are incorporated within the vehicle platform such that there is minimal or no physical overlap between the functional components and the area defined by the vehicle body.

Abstract: Described herein are methods and a system for that monitors the performance, and provides reporting including replacement of IoT edge devices in an edge computing network. Data is received by an AI/ML model from multiple IoT edge devices which is process in time series. Analysis services and engines determine the performance of the multiple IoT edge devices. Severity and weightage are applied to the data, and algorithms determine performance and replacement recommendations.

Abstract: A compressor module for a refrigerant circuit of a motor vehicle air-conditioning system, exhibiting a modular multi-part housing with a low-pressure refrigerant inlet, a high-pressure refrigerant outlet and a compressor, characterized in that an inner heat exchanger of the refrigerant circuit is produced such that it is integrated into the compressor module, wherein the housing of the compressor module fully encloses the inner heat exchanger.

Abstract: A deployment device for positioning a soft tissue repair prosthesis includes a self-expanding support body releasably attachable to the prosthesis. The support body may be removably insertable into a pocket of the prosthesis. A handle coupled to the support body facilitates positioning the patch and/or removal of the support body from the pocket. The support body may substantially occupy the pocket in an expanded configuration. The handle may be arranged to direct a pulling force to the outer peripheral edge of the support body and/or cause a portion thereof to be pulled downward and below the body during withdrawal of the deployment device from the prosthesis. The support body may include support segments pivotally coupled together and foldable to collapse the support body for insertion into and removal from the pocket. One or more resilient support members may be provided for collapsing and expanding the support body and the prosthesis.

Abstract: A connector assembly controllably couples a box having a plurality of containers containing a liquid, is provided. Each container has a fitment. The connector assembly includes a housing, a valve assembly, actuator and a locking plate. The valve assembly includes a plurality of fitment receptacles. The actuator is rotatably coupled to the housing and is movable between an open position, a closed position and an engaged position. The locking plate assembly includes a plurality of opening corresponding to each fitment. The opening has a first diameter when the actuator is in the open position. The first diameter of the opening is configured to allow entry of the fitments into the opening. Movement of the actuator from the open position to the closed position closes the opening to a second diameter.

Abstract: A method of forming a structure for etch masking that includes forming first dielectric spacers on sidewalls of a plurality of mandrel structures and forming non-mandrel structures in space between adjacent first dielectric spacers. Second dielectric spacers are formed on sidewalls of an etch mask having a window that exposes a connecting portion of a centralized first dielectric spacer. The connecting portion of the centralized first dielectric spacer is removed. The mandrel structures and non-mandrel structures are removed selectively to the first dielectric spacers to provide an etch mask. The connecting portion removed from the centralized first dielectric spacer provides an opening connecting a first trench corresponding to the mandrel structures and a second trench corresponding to the non-mandrel structures.

Abstract: Foldable vehicle cover (armed/unarmed) covers vehicle's front, mid-section, and rear, longitudinally, laterally and vertically. Longitudinal staves in separate cover segments permit lateral collapse of cover with draw cords in lateral cover channels (one cord-end attached at closed channel end and the cord extending outboard from open channel end). The unarmed cover has four operating modes: covered, uncovered, laterally compressed and folded (front and rear segments folded atop mid-sectional segment). An alarmed cover includes either pouches on inboard side of vertical cover portions or module attachment systems on the inboard side. Proximity alarm module is pouch mounted or attached and is removably coupled to vehicle vertical element via an electromagnetic/mechanical attachment sub-system. A proximity sensor generates ALARM sensor not proximate vehicle element. A transmitter generates RF ALARM and a software App on user's causes ALARM annunciation.

Abstract: An oral care implement including an elongated body having a head portion supporting plurality of tooth cleaning elements and a handle portion defining an outer surface. A grip control component is disposed on the handle portion and includes a pair of transversely spaced apart control surfaces separated by a longitudinally extending channel. The control surfaces are elevated above the outer surface of the handle portion and positioned to engage a user's thumb. The control component is operable to tilt the head portion at an upward or downward angle relative to a vertical plane of a user's teeth when the control component is grasped between the user's thumb and forefinger for producing a proper brushing angle at the gum line.

Abstract: A headgear system and/or an interface assembly incorporating a headgear system that, in some configurations, is configured to transform from elasticated or “stretchy” behavior to “inelastic” behavior at least in response to normal or expected forces encountered during the intended therapy. In some configurations, upon fitment to the head of a user, the system automatically adjusts toward or to an appropriate size. A headgear portion or assembly for use in combination with a breathing apparatus in some configurations is at least substantially inelastic and is three dimensional in shape. The headgear portion or assembly can comprise a plastic core and a textile casing. The headgear, or part thereof, may also have integrally moulded labels, connectors, adjustment mechanisms and/or grips.

Abstract: A method for operating a friction brake device for an electrically propelled vehicle, in particular a utility vehicle, with an electric drive capable of regenerative braking, the method having the following steps: determining whether braking by the friction brake device is necessary for lining maintenance, causing braking by the friction brake device based on a brake parameter, determining drive information concerning the electric drive, and modifying the brake parameter and a drive parameter depending on the drive information in order to achieve lining maintenance, wherein the drive parameter causes operation of the electric drive depending on the braking.

Abstract: A method is disclosed for characterizing an acoustic-based particle manipulation device comprising a sample holder having a holding space containing a fluid medium. The holding space comprises a wall surface portion. The method comprises providing a driving signal to the sample holder for generating an acoustic wave in the holding space that drives a particle at the wall surface portion, away from the wall surface portion. The method further comprises measuring vibrations of at least part of a surface of the sample holder caused by said driving signal. The method also comprises, based on the measured vibrations of said at least part of the surface, determining, for each position out of a plurality of positions at the wall surface portion and in the holding space, a value for an acoustic force that is caused by said driving signal and that acts in a direction away from the wall surface portion.