Patents by Inventor Fen JIANG

Fen JIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic derivative and use thereof
    Patent number: 12458647
    Abstract: The present disclosure discloses a class of macrocyclic derivatives, and specifically discloses a compound shown in formula (VI), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 3, 2025
    Date of Patent: November 4, 2025
    Assignee: Guangzhou Joyo Pharmatech Co., Ltd.
    Inventors: Yang Zhang, Kai Zhou, Fen Jiang, Li Zhang, Xiao Liu, Zheng Wang, Kevin X. Chen, Jian Li, Shuhui Chen
  • MACROCYCLIC DERIVATIVE AND USE THEREOF
    Publication number: 20250268907
    Abstract: The present disclosure discloses a class of macrocyclic derivatives, and specifically discloses a compound shown in formula (VI), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 5, 2025
    Publication date: August 28, 2025
    Inventors: Yang ZHANG, Kai ZHOU, Fen JIANG, Li ZHANG, Xiao LIU, Zheng WANG, Kevin X. CHEN, Jian LI, Shuhui CHEN
  • MACROCYCLIC DERIVATIVE AND USE THEREOF
    Publication number: 20250205245
    Abstract: The present disclosure discloses a class of macrocyclic derivatives, and specifically discloses a compound shown in formula (VI), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 3, 2025
    Publication date: June 26, 2025
    Inventors: Yang ZHANG, Kai ZHOU, Fen JIANG, Li ZHANG, Xiao LIU, Zheng WANG, Kevin X. CHEN, Jian LI, Shuhui CHEN
  • Pyrrolo[2,1-f][1,2,4]triazine derivatives serving as selective HER2 inhibitors and application thereof
    Patent number: 12030897
    Abstract: The present invention relates to a group of pyrrolo[2,1-f][1,2,4]triazine derivatives serving as selective HER2 inhibitors and an application thereof in the preparation of a drug that serves as an HER2 inhibitor. Specifically, the present invention relates to a compound represented by formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: July 9, 2024
    Assignee: MEDSHINE DISCOVERY INC.
    Inventors: Kevin X Chen, Fen Jiang, Xinde Chen, Li Zhang, Zhaoguo Chen, Yanxin Yu, Kai Zhou, Boyu Hu, Cheng Xie, Shuhui Chen
  • PYRIMIDOPYRROLE SPIRO COMPOUNDS AND DERIVATIVES THEREOF AS DNA-PK INHIBITORS
    Publication number: 20230055321
    Abstract: Provided are a class of DNA-PK inhibitor, and specifically, a compound represented by formula (III) or a pharmaceutically acceptable salt thereof, and use thereof in the preparation of DNA-PK inhibitor-related drugs.
    Type: Application
    Filed: November 20, 2020
    Publication date: February 23, 2023
    Inventors: Kevin X CHEN, Shanghua XIA, Zhaoguo CHEN, Zuhao GUO, Yanxin YU, Kai ZHOU, Boyu HU, Li ZHANG, Fen JIANG, Jingjing WANG, Guoping HU, Jian LI, Shuhui CHEN
  • PYRIMIDOIMIDAZOLE COMPOUNDS USED AS DNA-PK INHIBITORS
    Publication number: 20230026616
    Abstract: A class of DNA-PK inhibitors, in particular a compound represented by formula (IV) or a pharmaceutically acceptable salt thereof, and an application thereof in the preparation of a drug relating to a DNA-PK inhibitor.
    Type: Application
    Filed: November 25, 2020
    Publication date: January 26, 2023
    Inventors: Kevin X CHEN, Shanghua XIA, Zhaoguo CHEN, Zuhao GUO, Yanxin YU, Kai ZHOU, Boyu HU, Li ZHANG, Fen JIANG, Jingjing WANG, Guoping HU, Jian LI, Shuhui CHEN
  • SALT AND CRYSTAL FORM OF MTORC1/2 DUAL KINASE ACTIVITY INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20220306622
    Abstract: Disclosed are a salt and a crystal form of an mTORC1/2 dual kinase inhibitor and a preparation method therefor. Also disclosed is use of the salt and crystal form in the preparation of a medicament related to the mTORC1/2 dual kinase inhibitor.
    Type: Application
    Filed: May 6, 2020
    Publication date: September 29, 2022
    Inventors: Kevin X CHEN, Zhaoguo CHEN, Li ZHANG, Yanxin YU, Kai ZHOU, Fen JIANG, Shanghua XIA, Xiaofei WANG
  • PYRROLO[2,1-F][1,2,4]TRIAZINE DERIVATIVES SERVING AS SELECTIVE HER2 INHIBITORS AND APPLICATION THEREOF
    Publication number: 20210323979
    Abstract: The present invention relates to a group of pyrrolo[2,1-f][1,2,4]triazine derivatives serving as selective HER2 inhibitors and an application thereof in the preparation of a drug that serves as an HER2 inhibitor. Specifically, the present invention relates to a compound represented by formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 8, 2019
    Publication date: October 21, 2021
    Applicant: MEDSHINE DISCOVERY INC.
    Inventors: Kevin X CHEN, Fen JIANG, Xinde CHEN, Li ZHANG, Zhaoguo CHEN, Yanxin YU, Kai ZHOU, Boyu HU, Cheng XIE, Shuhui CHEN