Abstract: The present application relates to an array substrate and a display panel. In the present application, a first common line and a first sharing line are respectively disposed on two sides of a scan line, thereby preventing a situation in the prior art that the first sharing line penetrates a main pixel region and a sub-pixel region vertically, thereby improving an aperture ratio and a transmittance of the array substrate. The first common line, the first sharing line, and the scan line are disposed in a same layer, thereby further improving the transmittance of the array substrate.

Abstract: A liquid crystal display panel, a driving method, and a terminal thereof are disclosed. The display panel includes a pixel structure including data lines and scan lines, wherein each data line is connected to at least two pixel groups, and each pixel group includes three sub-pixels having different colors sequentially connected to the data lines; and a first driving unit electrically connected to the scan lines and inputting scan signals to the scan lines in a preset order to solve a problem of horizontal bright and dark lines.

Abstract: Provided is an angle-adjustable positioning and self-closing hinge for a highly sealed door, comprising a hinge part, a fixing base, a fixing bar, a threaded sleeve, a threaded ring, a plug, and an adjustment socket; the hinge part is provided with a bushing and a leaf; the fixing base is provided with a bushing; the fixing bar has a screw; a threaded sleeve is fastened inside the bushing, the plug is fastened inside the bushing, and the threaded sleeve and plug are spaced apart; between the threaded sleeve and plug in the two bushings are disposed the fixing bar, the two magnets, two springs, and the adjustment base; the screw of the fixing bar is screwed to the threaded sleeve.

Abstract: An adjustable-angle positioning and self-closing hinge has two hinge leaves, a fixing pin, a screw knuckle, a screw ring, a fixing base, and an adjusting base; each leaf of the hinge comprises a knuckle and a leaf fastened outside the knuckle; the fixing pin has a threaded pin; the screw knuckle is fastened inside the knuckle of one of the hinge leaves, the fixing base is fastened inside the knuckle of one of the hinge leaves, and the screw knuckle and the fixing base are spaced separately; between the screw knuckle and fixing base in the knuckles of the two hinge leaves are disposed the fixing pin, the screw ring, two magnets, springs, and the adjusting base; the threaded pin of the fixing pin is screwed to the screw knuckle; a first spring abuts between the fixing pin and the front ring edge and gasket of a cup body.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: The present invention provides compositions, methods, and kits for identifying agents that are capable of disrupting protein-protein interaction in a mammalian reverse two-hybrid system. A tetracycline repressor protein was fused with the inhibitory KRAB domain as a suppressor to tightly regulate the reverse two-hybrid system for mammalian cells. Binding of the chimeric protein to the tetracycline operator sequence provided within a promoter entirely suppressed the expression of two interactive proteins. When both an inducer and a candidate protein-protein interaction disrupting agent such as a drug were added in the cell culture together, the reporter gene was either activated by the interaction of protein-pair if the drug was ineffective or remained silent due to the disruption of the protein-protein interaction by the effective drug. The plasmids for the suppressor and the reporter were integrated into chromosomes.

Abstract: The invention features methods of treating insulin-induced obesity, weight gain, and other conditions associated with hyperinsulinemia.