Abstract: An array substrate and a display panel including a plurality of pixels, a plurality of scan line groups and a plurality of data lines, each of the pixels includes at least three sub-pixels, each of the scan line group includes three sub-scan lines, one of the scan line groups is provided between adjacent two of the pixel rows, and at least two of the sub-pixels in each of the pixels are connected to different two of the sub-scan lines in the one of the scan line groups, one of the pixel columns is provided between adjacent two of the data lines, and at least two of the sub-pixels in each of the pixels are connected to a same one of the data lines.

Abstract: The present application discloses a liquid crystal display panel, a driving method thereof, and a display device. The liquid crystal display panel includes a pixel structure, which includes a plurality of sub-pixels arranged in a matrix; data lines and scan lines arranged perpendicularly cross each other, wherein each of the sub-pixel groups includes two of the sub-pixels of same color; a first driving unit electrically connected to the scan lines, wherein the first driving unit inputs scan signals to the scan lines in a preset sequence, the sub-pixel groups of the pixel modules sequentially obtain the scan signals, two of the sub-pixels in each of the sub-pixel groups obtain the scan signals at a same time, and two of the sub-pixels in a same one of the sub-pixel groups obtain the scan signals at a same time.

Abstract: The disclosure provides a display panel and a preparation method thereof. The display panel includes an array substrate and an opposite substrate. The array substrate includes a first substrate, a common electrode layer, a first metal layer, a second substrate, and a light-shielding layer. The common electrode layer includes a common electrode, a first electrode, and a groove, and the groove is disposed between the common electrode and the first electrode. The light-shielding layer includes a light-shielding part, and an orthographic projection of the light-shielding part on the first substrate covers an orthographic projection of the first electrode on the first substrate, an orthographic projection of the second electrode on the first substrate, and an orthographic projection of the groove on the first substrate.

Abstract: Provided is an angle-adjustable positioning and self-closing hinge for a highly sealed door, comprising a hinge part, a fixing base, a fixing bar, a threaded sleeve, a threaded ring, a plug, and an adjustment socket; the hinge part is provided with a bushing and a leaf; the fixing base is provided with a bushing; the fixing bar has a screw; a threaded sleeve is fastened inside the bushing, the plug is fastened inside the bushing, and the threaded sleeve and plug are spaced apart; between the threaded sleeve and plug in the two bushings are disposed the fixing bar, the two magnets, two springs, and the adjustment base; the screw of the fixing bar is screwed to the threaded sleeve.

Abstract: An adjustable-angle positioning and self-closing hinge has two hinge leaves, a fixing pin, a screw knuckle, a screw ring, a fixing base, and an adjusting base; each leaf of the hinge comprises a knuckle and a leaf fastened outside the knuckle; the fixing pin has a threaded pin; the screw knuckle is fastened inside the knuckle of one of the hinge leaves, the fixing base is fastened inside the knuckle of one of the hinge leaves, and the screw knuckle and the fixing base are spaced separately; between the screw knuckle and fixing base in the knuckles of the two hinge leaves are disposed the fixing pin, the screw ring, two magnets, springs, and the adjusting base; the threaded pin of the fixing pin is screwed to the screw knuckle; a first spring abuts between the fixing pin and the front ring edge and gasket of a cup body.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: A chimeric transactivator comprises a transcription activation domain, a repressor protein DNA binding domain and the bacterial DNA gyrase B subunit. A target gene is operatively linked to operator DNA sequences recognized by the repressor binding domain. The addition of the antibiotic coumermycin results in a coumermycin-switched dimerization of the transactivator, which then binds to operator DNA sequences and activates transcription of the target gene. The addition of novobiocin switches off expression of the target gene by abolishing coumermycin-induced dimerization of the transactivator.

Abstract: The present invention provides compositions, methods, and kits for identifying agents that are capable of disrupting protein-protein interaction in a mammalian reverse two-hybrid system. A tetracycline repressor protein was fused with the inhibitory KRAB domain as a suppressor to tightly regulate the reverse two-hybrid system for mammalian cells. Binding of the chimeric protein to the tetracycline operator sequence provided within a promoter entirely suppressed the expression of two interactive proteins. When both an inducer and a candidate protein-protein interaction disrupting agent such as a drug were added in the cell culture together, the reporter gene was either activated by the interaction of protein-pair if the drug was ineffective or remained silent due to the disruption of the protein-protein interaction by the effective drug. The plasmids for the suppressor and the reporter were integrated into chromosomes.

Abstract: The invention features methods of treating insulin-induced obesity, weight gain, and other conditions associated with hyperinsulinemia.