Abstract: Disclosed is an interleukin-2 (IL-2) variant with decreased binding affinity to the IL-2 receptor, and a recombinant protein containing the IL-2 variant.

Abstract: A package arrangement is provided, including a base panel and a first accommodating portion provided on the base panel. The first accommodating portion is configured to be able to retain an item to be packaged, while allowing at least part thereof to be exposed and visible outside the first accommodating portion.

Abstract: Model hub orchestration includes identifying, by a model scheduler of a model hub orchestrator in response to a request from a client device, a plurality of processing blocks of a machine learning model. The model scheduler assigns each processing block an index indicating a position of the processing block within a sequential arrangement of the plurality of processing blocks of the machine learning model. The model scheduler selects one or more model hubs communicatively coupled with the model hub orchestrator to store different ones of the plurality of processing blocks. The model scheduler transfers the plurality of processing blocks from the client device to the one or more model hubs as selected.

Abstract: A cell culture device comprises a multi-well cell culture plate comprising a plurality of wells, each well comprising a top, a bottom, and a sidewall disposed between the top and the bottom and having an interior surface comprising an ultra-low attachment surface. A plurality of scaffolds are disposed within wells of the multi-well cell culture plate, each scaffold comprising a cell-adherent surface. In some embodiments, the scaffold comprises a fiber scaffold. In some embodiments, the scaffold comprises an artificial vascular scaffold. In some embodiments, cell culture devices comprise a plurality of hydrogel scaffolds disposed in a multi-well cell culture plate, the plurality of hydrogel scaffolds comprising hydrogel fibers of differing lengths, wherein opposite ends of a hydrogel fiber are disposed in different wells within the multi-well cell culture plate to create interconnected wells.

Abstract: An electric pump rotor includes: a permanent magnet; a cylindrical rotor core that holds the permanent magnet; an adjacent member that is provided adjacent to one side in an axial direction of the permanent magnet and the rotor core; and a resin molded portion in which a drive unit that covers the permanent magnet, the rotor core, and the adjacent member, and a blade portion that pressure-feeds a working fluid are integrally formed by resin molding.

Abstract: A base station includes a base station body and a base station addressing device. The base station addressing device includes: an acquisition module configured to acquire satellite observation data at a current observation point; a calculation module configured to evaluate the observation quality at the observation point according to the satellite observation data; and an output module configured to output a first prompt according to the observation quality, where the first prompt indicates the suitability of the observation point for mounting the base station. The base station addressing device is detachably connected to the base station body so that the base station addressing device is capable of being detached from the base station body to perform an addressing task.

Abstract: The present disclosure relates to the technical field of clothing treatment, and particularly provides a clothing treatment device, aiming at solving the problem in the prior art where a connecting structure between a drawer and a box body is unable to effectively withstand both horizontal and vertical forces simultaneously. To this end, the clothing treatment device of the present disclosure includes a first moving component, a second moving component, and a pull-out working component. An inclined surface of which an angle can be adjusted by a pull rope is arranged on the first moving component. A support component is arranged on the working component, and the first moving component is arranged on the working component. In the pull-out process of the working component, the clothing treatment device enables the first moving component to drive the working component to move on the second moving component.

Abstract: A self-propelled device includes a housing; a traveling assembly including traveling wheels and a traveling electric motor, where the traveling assembly is coupled to the housing; and a mobile station including a satellite receiving antenna and a radio station, where the satellite receiving antenna is configured to acquire a satellite signal, the satellite signal includes satellite observation data of the mobile station, the radio station is configured to receive a radio signal from a base station, and the radio signal includes satellite observation data of the base station. The self-propelled device further includes a controller configured to control the self-propelled device to autonomously travel and perform a work task.

Abstract: A child seat device includes a backrest, a seat and a tether system. The backrest is rotatably connected to the seat. The seat device has a sitting side and a back side. The tether system comprises a shoulder strap and a crotch strap. The shoulder strap is arranged on the backrest. The crotch strap has a connecting end and a fixed end. The portion of the crotch strap on the sitting side is a first strap segment. The connecting end is located on the first strap segment and can be detachably connected to one end of the shoulder strap. The fixed end is fixedly connected to the back side of the seat device.

Abstract: In one aspect, the present disclosure relates to compounds of Formula (I), which inhibit Activin A receptor type 1 (ACVR1 or ALK2) and/or mutants thereof, and pharmaceutical compositions thereof, and/or which inhibit Activin A receptor like type 1 (ACVRL1 or ALK1) and/or mutants thereof, and pharmaceutical compositions thereof. In another aspect, the present disclosure provides a method of treating, preventing, and/or ameliorating a disease and/or disorder in a subject, the method comprising administering to the subject at least one compound and/or pharmaceutical composition of the present disclosure. In certain embodiments, the disease and/or disorder is characterized by one or more ACVR1 and/or ACVRL1 activating mutations and/or overactive ACVR1 and/or overactive ACVRL1.

Abstract: A model prediction-based control method for grid forming of multi-port autonomous reconfigurable solar plants includes: estimating and predicting system parameters by establishing a multi-port autonomous reconfigurable solar plant and a dynamic model of a synchronous generator model; converting an objective function into an unconstrained optimization problem, using Newton's method to achieve minimum computational burden within each calculation time step to find a solution in real time for obtaining an optimal angular frequency; based on results of the optimal angular frequency, updating an output voltage and a dq-axis current of the multi-port autonomous reconfigurable solar plant, and changing an arm modulation index of the plant, thereby realizing the plant's inertia and primary frequency modulation support. The model prediction-based control method provided by the present invention achieves rapid prediction during operation and improves frequency response, rapidity and system stability.

Abstract: Provided herein are a set of primers and probes for detecting rotavirus.

Abstract: Provided are an organic electroluminescent material and device. The organic electroluminescent material is a compound having a structure of Formula 1. The compound may be used as a host material, an electron transporting material, or a hole blocking material in an organic electroluminescent device and can greatly improve device performance, for example, improve device efficiency and achieve an unexpectedly significant improvement in device lifetime. Further provided are an organic electroluminescent device comprising the organic electroluminescent material and a compound composition comprising the organic electroluminescent material.

Abstract: Disclosed is a clamping tool, including a first plier body, a second plier body, and a pivot connection locking mechanism, wherein the first plier body includes a first handle body and a first plier head; the second plier body includes a second handle body and a second plier head, the second plier body being hinged with the first plier body; the pivot connection locking mechanism is movably arranged at a position where the first plier body is hinged with the second plier body; the pivot connection locking mechanism has an unlocked state and a locked state; when in the locked state, the first plier head is pivotally connected with the second plier head; and when in the unlocked state, the first plier head and the second plier head can move toward or away from each other.

Abstract: The disclosure relates to the technical field of traction batteries, and in particular to a battery pack and a vehicle comprising the battery pack. The invention aims at the problem of large heat loss in the existing traction battery in a low-temperature environment. To this end, the battery pack of the disclosure comprises: a frame internally formed with an installation site; a battery module mounted in the installation site and comprising a number of cells; and a side beam connected to an outer side wall of the frame and made of a first thermal insulation material. The above arrangement can reduce the heat transfer coefficient of natural convection between the side wall of the frame and the environment, and reduce the heat flux, thereby reducing the temperature loss of the cells.

Abstract: A filter element assembly and a water purifier. The filter element assembly includes: a first housing having a first water port, a second water port, a third water port, and a fourth water port; a first filter element having a first water channel and a second water channel; a second housing; a second filter element, a third water channel and a fourth water channel being provided at an outer periphery and an inner periphery of the second filter element, respectively; a first pipeline connected between the third water port and a fifth water port and arranged in the second water channel; and a second pipeline connected between the fourth water port and a sixth water port arranged within the second water channel and spaced apart from the first pipeline.

Abstract: Provided are a CLDN18.2-combined antibody and an unfucosylated form thereof. Further provided are a preparation method for the antibody, a conjugate, and a composition containing the antibody, and use thereof in the treatment of a disease such as cancer.

Abstract: A VoIP call method includes: receiving a VoIP call message sent by an application server of a first VoIP application through a push server, where the VoIP call message is used to request to perform a VoIP call; starting a first VoIP lightweight process of the first VoIP application, and providing the VoIP call message to the first VoIP lightweight process; displaying a call notification based on the VoIP call message obtained by the first VoIP lightweight process; and the first VoIP lightweight process establishes a persistent connection to the application server.

Abstract: A scanning assistance system and method is described. The scanning assistance system is connected to an imaging device. The scanning assistance system includes: a classification module, which selects a classifier based on a type of information input in the scanning process, to obtain feature data and question context data corresponding to the information; a decision module, which performs a search in a pre-constructed knowledge base and selects a knowledge base capable of processing the feature data and the question context data; and a control module, which, extracts from a corresponding knowledge base a question corresponding to the feature data and the question context data and a knowledge context for resolving the question, and provides a solution corresponding to the question by using a large language model. A question can be resolved quickly in a scanning process, and a scanning procedure can be optimized.

Abstract: A multiwell plates for cell culture growth are disclosed having reduced maximum depths. The multiwell plates may further comprise a reduced skirt height.