Abstract: Compositions and methods are provided for immunization against equine rotavirus group B (ERVB). The compositions comprise ERVB structural proteins VP4, VP2, VP6, and VP7, or VP2, VP6, VP7, and a modified VP4, which can be assembled into virus-like particles (VLPs). The invention includes immunogenic compositions and vaccines for administration to non-human animals, including pregnant mares to confer passive immunity to foals. Methods of stimulating immune responses, preventing ERVB spread, conferring passive immunity, evaluating vaccine efficacy, detecting ERVB antibodies, and producing VLPs in baculovirus-infected insect cells are disclosed. The compositions may further include inactivation agents. Nucleotides and vectors encoding the ERVB proteins are also provided.

Abstract: A display substrate and a display device. The display substrate includes a base substrate, a light-shielding layer, a gate layer and a source-drain metal layer; the base substrate includes a display area and a peripheral area; the light-shielding layer is located on the base substrate; the gate layer is at a side of the light-shielding layer away from the base substrate; and the source-drain metal layer is at a side of the gate layer away from the light-shielding layer. The display area includes signal lines, and the peripheral area includes a lead wire region and a bonding region; the lead wire region includes lead wires connected to the signal lines, and extend, in the lead wire area, to the bonding area in a first direction; and the lead wires are distributed in the light-shielding layer, the gate layer and the source-drain metal layer.

Abstract: Image capture devices and methods may be used to pre-buffer media storage. The pre-buffering method includes recording an image capture segment of a variable bitrate input stream in a circular buffer. The circular buffer includes a number of recordable segments. The method includes recording a next image capture segment in a next adjacent recordable segment of the circular buffer if the next adjacent recordable segment of the predetermined number of recordable segments is available. The method includes overwriting an oldest recordable segment if the next adjacent recordable segment of the predetermined number of recordable segments is not available.

Abstract: A targeted nanoscale particle is bound to the outer surface of the targeted cell, and is composed of a plurality of proteins interconnected via a first binding site. The targeted nanoscale particle further comprises a second binding site, and is bound to the outer surface of a target cell via the second binding site. In an exemplary embodiment, the targeted nanoscale particle can promote the interaction between the two types of cells by simultaneously binding to a chimeric antigen receptor T cell and a leukemia cell, thereby promoting the recognition and killing of the leukemia cell by the chimeric antigen receptor T cell. In addition, the internal cavities of the proteins in the targeted nanoscale particle provide space for loading of a chemotherapeutic drug, thus realizing the combination therapy of the chimeric antigen receptor T cell and other therapies while loading the drug.

Abstract: A colorful TPU film capable of being hot-cut is provided, relating to the field of TPU technology. The colorful TPU film capable of being hot-cut includes a colorful layer and a TPU carrier layer arranged in sequence from top to bottom, the colorful layer includes raw materials in parts by weight: 45-55 parts of polyurethane pigment composite, 10-15 parts of epoxy resin, 13-17 parts of styrene-acrylic emulsion, 2-3 parts of sodium dodecyl sulfate, 5-6 parts of octylphenol polyoxyethylene ether, 1-2 parts of sodium bicarbonate, and 1-2 parts of potassium persulfate. The colorful TPU film capable of being hot-cut has strong tensile strength and adhesion, while the ability to be cut at high temperatures, making practical. The preparation method of the colorful TPU film capable of being hot-cut TPU film is easy to control, resulting the colorful TPU film capable of being hot-cut has stable quality and excellent comprehensive performance.

Abstract: A method for training an image processing model includes: acquiring a to-be-corrected eye image set matching a usage environment of the image processing model; performing style transfer on to-be-corrected eye images in the to-be-corrected eye image set through a style transfer network in the image processing model, to obtain a target eye image; acquiring a training sample matching the usage environment of the image processing model based on the to-be-corrected eye images and the target eye image, the training sample including object eye images matching different gaze positions; and training a correction network in the image processing model through the training sample matching the usage environment of the image processing model, to obtain a model update parameter matching the correction network, and generating a trained image processing model based on the model update parameter.

Abstract: An image noise reduction method including: obtaining a first image to be processed and a second image as a reference image; obtaining a block of the first image by dividing the first image; determining a motion intensity of the block based on the second image; obtaining filter coefficient description information matching the motion intensity based on: a first pixel difference of a first pixel point value of the first image and a second pixel point value of the second image, and a filter coefficient; obtaining a target pixel difference between a third pixel point value of the block and a fourth pixel point value of the second image; determining a target filter coefficient corresponding to the target pixel difference based on the filter coefficient description information; and determining a target noise reduction image of the first image based on the target filter coefficient.

Abstract: A video frame processing method, performed by a computer device, includes: receiving video frames carrying noise, wherein the video frames include an object; extracting poses of a part of the object; determining deflection degree values of the part based on the poses; generating a control signal based on the deflection degree values; obtaining updated deflection values based on backlash filtering of the control signal; and performing image processing on the video frames based on the updated deflection values.

Abstract: Novel direct thrombin inhibitors are provided herein, along with methods for their use as anticoagulants. The direct thrombin inhibitors described herein are useful in treating and/or preventing thromboembolism and bleeding or clotting disorders. Also provided herein are methods for inhibiting thrombin in a cell using the compounds and compositions described herein.

Abstract: A package arrangement includes a support board. The support board is formed of at least two layers of plate laminated and affixed together. Adjacent two plates of the at least two layers of plate define therebetween a cavity for receiving at least part of a hand tool. Each plate of the at least two layers of plate is fabricated from a material satisfying recycling requirements for the same class of materials.

Abstract: Provided are a GLP-1 (7-37) polypeptide analogue, a fatty acid-modified derivative of the analogue, and a medicament comprising the derivative. Further, also provided are a preparation method of the derivative, and use of the same in the preparation of a medicament.

Abstract: The application provides an isolated monoclonal antibody or an antigen binding portion thereof, that specifically binds to B7-H3. Also provided is a nucleic acid molecule that encodes the antibody or antigen binding portion thereof, and an expression vector, a host cell and a method for expressing the antibody or antigen binding portion thereof. The application further provides an immunoconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus, and a pharmaceutical composition that comprise the antibody or antigen binding portion thereof, and a treatment method using the antibody or antigen binding portion thereof of the disclosure.

Abstract: The present invention relates to the field of optoelectronic communication and provides a module with a network interface. The module with a network interface comprises a base, a circuit assembly, and shielding elastic sheets. The base is provided with a screw seat thereon, and a first boss is provided on a side surface of the base. The circuit assembly comprises a circuit board, a network interface, and a grounding spring sheet. The circuit board is provided with a first notch which is coupled to a side wall of the screw seat; the grounding spring sheet is fixed on the circuit board and connected to the base. The shielding elastic sheet comprises two oppositely arranged side walls, each of which is provided with a folded edge, wherein the folded edge has a first buckling hole, which is buckled into the first boss to fix the shielding elastic sheet on the base.

Abstract: A TPU high and low temperature film with optical color effect and a preparation method thereof are provided. The TPU high-temperature film includes an optical coating layer, a texture layer, a TPU carrier layer, and a hot melt adhesive layer from top to bottom. The texture layer is made of polyurethane UV adhesive coating. The TPU high and low temperature film of the present disclosure has stable quality, excellent tensile properties, UV aging resistance, hydrolysis resistance, and boiling resistance. At the same time, its optical coating layer also has good adhesion, hydrolysis resistance, boiling resistance, and aging resistance, rendering it easy to use. The preparation method of the TPU high and low temperature film is simple in process, easy to control in operation, and conducive to industrial production. Moreover, during the production process, no waste, wastewater, exhaust gas, etc. are generated, which does not pollute the environment.

Abstract: An optical fiber connector and an optical splitter are provided, and pertain to the field of optical communication technologies. The optical fiber connector includes a housing and a plurality of optical fibers arranged in parallel. The housing encloses the plurality of optical fibers, and end faces at both ends of the optical fibers are exposed outside the housing. A part that is of at least one of the plurality of optical fibers and that is enclosed by the housing is provided with a grating, and when at least two optical fibers in the at least one optical fiber are provided with gratings, the gratings on the at least two optical fibers are different from each other. A grating on at least one optical fiber is provided on a part that is of the optical fiber and that is enclosed by the optical fiber connector.

Abstract: A heat exchanger, an electric control box, and an air conditioning system. The heat exchanger includes a heat exchange body and a collecting tube assembly. Multiple micro-channels are disposed in the heat exchange body. The collecting tube assembly includes at least two collecting tubes. At least a portion of the micro-channels passes through one collecting tube of the at least two collecting tubes and are communicated with a remaining one of the at least two collecting tubes.

Abstract: A building photovoltaic data interpolation method based on WGAN and whale optimization algorithm is provided, which includes: obtaining historical building roof photovoltaic output data, perform preprocessing on the historical building roof photovoltaic output data, and uses CNN to build a GAN; describing missing value position of preprocessed data by using a binary mask matrix, and setting Wasserstein distance to define a loss function of a GAN generator and a discriminator; taking the loss function as a fitness function, optimizing an input to the GAN generator through a whale optimization algorithm and obtaining optimized candidate samples; fusing the optimized candidate samples and a photovoltaic data processed by the binary mask matrix to obtain completed reconstructed samples, so as to improve the complementary accuracy, optimize the random noise, remove the unfavorable influencing components, and provide services for building rooftop PV data interpolation more accurately.

Abstract: Provided is an amorphous silicon thin-film transistor including an amorphous silicon semiconductor layer, a source electrode, and a drain electrode that are successively disposed on a base substrate. Ions doped by an ion implantation process are present in a region, proximal to the source electrode and the drain electrode, of the amorphous silicon semiconductor layer. A concentration of the ions in a surface region, proximal to the source electrode and the drain electrode, of the amorphous silicon semiconductor layer is greater than or equal to 5*10{circumflex over (?)}20 atoms/cc.

Abstract: Provided are a bispecific antibody and a preparation method therefor. The antibody comprises structural domains capable of binding to CD20 and CD3, and a heterodimer Fc region. The structural domains capable of binding to CD20 and CD3 are each independently selected from a Fab region, a ScFv region, or an sDab region. The bispecific antibody targets CD20 and CD3, and mediates T cell-specific killing of tumor cells.