Abstract: The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelination and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described.

Abstract: An electrical connector has a receiving space (10) and includes an insulative housing (1) and a set of contacts. The insulative housing includes a tongue portion (12) protruding into the receiving space. The tongue portion has a mating face (14), a set of depressions (141) formed in a front region of the mating face, and a set of passageways (142) defined in a rear region of the mating face and being spaced away from the depressions. The contacts are held in the tongue portion and include a set of first and second contacts (21,22). The first contacts have elastic first contact portions (15) being movably received in the passageways and protruding beyond the mating face and into the receiving space, and first tail portions (16) opposite to the first contact portions. The second contacts have stiff second contact portions (25) retained in the depressions and exposed to the receiving space, and second tail portions (28) opposite to the second contact portions.

Abstract: A method for forming micro-texture on an air bearing surface of a magnetic read/write slider, includes: positioning sliders arranged in arrays on a tray, each slider having a pole tip facing upward; loading the tray into a processing chamber, which is then evacuated to a preset pressure; and introducing a processing gas containing oxygen into the processing chamber; exposing the sliders to etch the surface of the slider so as to form a clear two-step structure thereon.

Abstract: An electrical connector has a receiving space (10) and includes an insulative housing (1) and a set of contacts. The insulative housing includes a tongue portion (12) protruding into the receiving space. The tongue portion has a mating face (14), a set of depressions (141) formed in a front region of the mating face, and a set of passageways (142) defined in a rear region of the mating face and being spaced away from the depressions. The contacts are held in the tongue portion and include a set of first and second contacts (21,22). The first contacts have elastic first contact portions (15) being movably received in the passageways and protruding beyond the mating face and into the receiving space, and first tail portions (16) opposite to the first contact portions. The second contacts have stiff second contact portions (25) retained in the depressions and exposed to the receiving space, and second tail portions (28) opposite to the second contact portions.

Abstract: The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelination and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described.

Abstract: An electrical connector for being mounted on a PCB, has a receiving space (10) and includes an insulative housing (1) having a tongue portion (12) being parallel to the PCB, the tongue portion having a mating face (14), a set of depressions (141) formed in a front region of the mating face, and a set of passageways (142) formed in a rear region of the mating face; and a set of contacts including a set of first and second contacts (21,22). The first contacts have elastic first contact portions (15) being movably received in the passageways, first tail portions (16), and first connecting portions (17) extending along the tongue portion. The second contacts have stiff second contact portions (25) received in the depressions, second tail portions (28), and second connecting portions (27) being parallel to the first connecting portions in a height direction of the tongue portion. The second contact portions (27) are located at an inner side of the mating face (14).

Abstract: An electrical connector for being mounted on a PCB, has a receiving space (10) and includes an insulative housing (1) having a tongue portion (12) being parallel to the PCB, the tongue portion having a mating face (14), a set of depressions (141) formed in a front region of the mating face, and a set of passageways (142) formed in a rear region of the mating face; and a set of contacts including a set of first and second contacts (21,22). The first contacts have elastic first contact portions (15) being movably received in the passageways, first tail portions (16), and first connecting portions (17) extending along the tongue portion. The second contacts have stiff second contact portions (25) received in the depressions, second tail portions (28), and second connecting portions (27) being parallel to the first connecting portions in a height direction of the tongue portion. The second contact portions (27) are located at an inner side of the mating face (14).

Abstract: An electrical connector mounted on a mother PCB includes an insulative tongue portion and a number of contacts held in the insulative tongue portion. The contacts have four conductive contacts and at least one pair of differential contacts for transferring high speed signals. The conductive contacts are adapted for USB 2.0 protocol. The contacts include a plurality of first and second tail portions to be arranged in a single row or at least two rows.

Abstract: An electrical connector includes an housing having a base portion, a tongue portion extending forwardly from the base portion and a number of passageways, the tongue portion defining a front face, a first side face and a second side face; a metal shell enclosing the tongue portion to define a receiving room therebetween, and defines a top wall, bottom wall and a pair of side walls, a first receiving room being formed between the bottom wall and the first side face; a number of contacts received in the passageways respectively and including a plurality of first contacts and second contacts, the first contacts each defining a first contacting portion, a first soldering portion and a first retaining portion, the second contacts each defining a second contacting portion, a second soldering portion and a second retaining portion.

Abstract: A updating method of images in electronic paper panel includes: divide the screen and image into (N*N) areas and build indexes for them; compare the present image on the display screen with the next image and compute the different areas; according to the computing result, find the uppermost, undermost, leftmost and rightmost different areas and compute the area of the smallest rectangle which includes the different areas; compare the result with the configured threshold and according to this compared result, set up the updating method to display the image. This method effectively reduces the data of updating images and save the power of the electronic paper, especially the power of the electronic paper panel. It can also improve the response time of the electronic paper panel. At the same time, it is easy to be ported to other advanced embedded operating systems. Thus, it could provide an effective method for the products related to the electronic paper.

Abstract: A display method of images in electronic paper panel includes: set the resolution for display; add a new event which indicates and drives the new image display; trim the new image to fit in with the resolution; compress the image when it needs to be stored, only reserve the mean values of pixels within each column and each row, as the character of the image; compare the next image with the present image and get the correlation coefficient of the two images; according to the correlation coefficient, set a proper display mode; enhance the image based on human visual character, and then display image. This invention extends the application of electronic paper to intelligent operating system areas, and it is easy to be ported to different advanced intelligent operating systems. It can significantly eliminate the ghosting and flicker on the electronic paper panel, and it also reduces the power consumption of the electronic paper systems and reduces the response time for display.

Abstract: Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.

Abstract: A stacked electrical connector includes a first mating interface. The first mating interface comprises a first receiving space (101) with a first tongue (102). The first tongue (102) has a pair of upper and lower face (1021, 1022). A plurality of first contacts (20) are retained in the first mating interface. The first contacts (20) include a plurality of first elastic contacts (201) and a plurality of first flat contact (202). Each first elastic contact (201) has a securing portion (2011) fixed in the first mating interface (101), an elastic contact portion (2010) extending to the first tongue (102) and a soldering portion (2012). Each first flat contact (202) has a retention portion (2024, 2028) retained in the first mating interface (101), a flat contact portion (2022, 2026) extending to the first tongue (102) and a tail portion (2025, 2029).

Abstract: An electrical connector includes an housing having a base portion, a tongue portion extending forwardly from the base portion and a number of passageways, the tongue portion defining a front face, a first side face and a second side face; a metal shell enclosing the tongue portion to define a receiving room therebetween, and defines a top wall, bottom wall and a pair of side walls, a first receiving room being formed between the bottom wall and the first side face; a number of contacts received in the passageways respectively and including a plurality of first contacts and second contacts, the first contacts each defining a first contacting portion, a first soldering portion and a first retaining portion, the second contacts each defining a second contacting portion, a second soldering portion and a second retaining portion.

Abstract: A stacked electrical connector includes a first mating interface. The first mating interface comprises a first receiving space (101) with a first tongue (102). The first tongue (102) has a pair of upper and lower face (1021, 1022). A plurality of first contacts (20) are retained in the first mating interface. The first contacts (20) include a plurality of first elastic contacts (201) and a plurality of first flat contact (202). Each first elastic contact (201) has a securing portion (2011) fixed in the first mating interface (101), an elastic contact portion (2010) extending to the first tongue (102) and a soldering portion (2012). Each first flat contact (202) has a retention portion (2024, 2028) retained in the first mating interface (101), a flat contact portion (2022, 2026) extending to the first tongue (102) and a tail portion (2025, 2029).

Abstract: An electrical connector mounted on a mother PCB includes an insulative tongue portion and a number of contacts held in the insulative tongue portion. The contacts have four conductive contacts and at least one pair of differential contacts for transferring high speed signals. The conductive contacts are adapted for USB 2.0 protocol. The contacts include a plurality of first and second tail portions to be arranged in a single row or at least two rows.

Abstract: Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.

Abstract: Two novel benzofuran glycosides, named psoralenoide and isopsoralenoide, isolated and purified from the seeds of Psoralea corylifolia. The compounds are useful as therapeutic agents for diseases defined under TCM and as a more accurately means of quality control and assessment for Psoralea corylifolia, an important herbs used in TCM.