Abstract: The present invention provides fully human monoclonal antibodies that specifically bind to GPNMB, and uses thereof. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs) are provided. The present invention also provides immunoconjugates comprising anti-GPNMB antibodies and methods of using such immunoconjugates. The present invention further provides bi-specific antibodies comprising an anti-GPNMB antibody component and an anti-CD3 component, and methods of using such bispecific antibodies.

Abstract: Generally, this disclosure provides methods and systems for dynamic control of display brightness in different regions of the display based on window configuration and content. The method may include determining regions of interest to a user on the display; adjusting the display brightness in the regions of interest to a first level of brightness; and adjusting the display brightness in regions outside of the regions of interest to a second level of brightness, such that the second level of brightness is lower than the first level of brightness. The dynamic adjustment of display brightness in different regions of the display may reduce power consumption by the display.

Abstract: A wavelength-tunable laser system includes an optical fiber collimator array having at least two ports, an optical amplifier connected to one port of an optical fiber, an optical coupler for coupling light incident from the optical amplifier and transmitting the coupled light to another port, a diffraction grating plate for guiding each wavelength component of light incident from the optical fiber collimator array in a different direction, and an Opto-Very Large Scale Integration (Opto-VLSI) processor.

Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof.

Abstract: An electronic device defines a receiving groove for an antenna, a first opening, and a second opening. The first opening and the second opening are at two opposite ends of the receiving groove, and allow an antenna assembly to be extended or retracted in the receiving groove to allow the electronic device to receive different types of wireless signals.

Abstract: A multiple-input multiple-output (MIMO) device includes a substrate, a shielding cover and a MIMO antenna. The shielding cover is positioned on the substrate, and includes a plurality of sidewalls. The MIMO antenna includes a first solid antenna, a second solid antenna, and a plane antenna. The first solid antenna and the second solid antenna are electrically connected to two ends of one sidewall of the shielding cover, respectively. The first plane antenna is configured on the substrate, and disposed between the first solid antenna and the second solid antenna.

Abstract: A wavelength-tunable laser system includes an optical fiber collimator array having at least two ports, an optical amplifier connected to one port of an optical fiber, an optical coupler for coupling light incident from the optical amplifier and transmitting the coupled light to another port, a diffraction grating plate for guiding each wavelength component of light incident from the optical fiber collimator array in a different direction, and an Opto-Very Large Scale Integration (Opto-VLSI) processor.

Abstract: A hybrid imaging array and method for using the same is disclosed. The image array includes a low-light imaging array and a color imaging array. The two imaging arrays can be utilized separately or in conjunction with one another. The low-light imaging array is optimized for night vision or situations in which the light levels are too low to allow a conventional color image to be formed by the color imaging array. The color imaging array is optimized for daylight or color photography. The low-light imaging array can be utilized in conjunction with the color imaging array to provide a color image with reduced noise.

Abstract: Described are lithium iron phosphate cathode materials for lithium secondary batteries and methods of preparation thereof. Better cathode materials may be produced by two carbon processes. The first carbon process comprises mixing lithium compounds, iron compounds, phosphorous compounds and a first carbon additive, and heating the mixture to a first temperature. The second carbon process comprises adding a second carbon additive to the to the product of the first carbon process and heating the mixture to a second temperature. The cathode material so produced exhibits superior electrical properties.

Abstract: A card edge connector includes an elongated housing with a pair of latches disposed at opposite ends thereof and defining a mating groove in the housing and between said pair of latches. A first wall and a second wall are formed at opposite sides of the mating groove, on which a plurality of conductive terminals are mounted. A key protrudes into the mating groove from the first wall with a distal end sinking into the second such that the second wall can be molded in an uninterrupted manner without the joint of the key.

Abstract: A card edge connector includes an elongated housing with a pair of latches disposed at opposite ends thereof and defining a mating groove in the housing and between said pair of latches. A first wall and a second wall are formed at opposite sides of the mating groove, on which a plurality of conductive terminals are mounted. A key protrudes into the mating groove from the first wall with a distal end sinking into the second such that the second wall can be molded in an uninterrupted manner without the joint of the key.

Abstract: A process for preparing lithium-nickel-manganese-cobalt composite oxide used as a positive electrode material for the lithium ion battery, comprising subjecting a mixture containing a lithium compound and nickel-manganese-cobalt hydroxide to a first-stage sintering and a second-stage sintering. The process includes adding a binder and/or binder solution after the first-stage sintering, and the mixture of the binder and/or binder solution and the product of first-stage sintering is sintered in the second-stage sintering. The tap density and volume specific capacity of the positive electrode material lithium-nickel-manganese-cobalt composite oxide prepared by the process, come up to 2.4 g/cm3 and 416.4 mAh/cm3, respectively. Besides, the positive electrode material lithium-nickel-manganese-cobalt composite oxide prepared by the process possesses the advantages of high specific capacity and good cycle stability.

Abstract: A multiple-input multiple-output (MIMO) device includes a substrate, a shielding cover and a MIMO antenna. The shielding cover is positioned on the substrate, and includes a plurality of sidewalls. The MIMO antenna includes a first solid antenna, a second solid antenna, and a plane antenna. The first solid antenna and the second solid antenna are electrically connected to two ends of one sidewall of the shielding cover, respectively. The first plane antenna is configured on the substrate, and disposed between the first solid antenna and the second solid antenna.

Abstract: The present invention relates to additives for electrolytes of lithium ion secondary batteries that include one or more of the following: 1,3-propane sultone, succinic anhydride; ethenyl sulfonyl benzene, and halobenzene. It can also include biphenyl, cyclohexylbenzene; and vinylene carbonate. The weight of said 1,3-propane sultone is between 0.5 wt. % and 96.4 wt. %, said succinic anhydride is between 0.5 wt. % and 96.4 wt. %; said ethenyl sulfonyl benzene is between 0.5 wt. % and 95.2 wt. %; and said halobenzene is between 0.5 wt. % and 95.2 wt. % of the weight of the additive. Batteries with electrolytes containing said additives have improved over-charge characteristics and low temperature properties, and reduced gas generation during charging and discharging.

Abstract: Disclosed herewith are an additive mixture for the electrolyte of lithium ion secondary batteries and electrolyte of lithium ion secondary batteries comprising the said additive mixture. The additive mixture comprises biphenyl based compound 0.5-95.4 wt %, cyclohexyl benzene based compound 0.1-93.8 wt %, vinylene carbonate 0.4-93.2 wt %, t-alkyl benzene based compound 0.5-96.5 wt %, and phenyl vinyl sulfone 0.5-95.8% based on total weight of the additive mixture.

Abstract: This invention relates to non-aqueous electrolytes, in particular, a non-aqueous electrolyte for lithium-ion secondary batteries. The electrolyte comprises regular organic solvents and electrolyte saline. The special characteristics are: the electrolyte also comprises mixed additives, said mixed additives comprising at least one of those of compound group A, at least one of those of compound group B, and one of those of compound group C wherein: compound group A are selected from inorganic saline including Li2CO3, Li2SO4, Li2SO3, LiNO3; compound group B are selected from vinylene carbonate, propylene carbonate; and compound group C are selected from ES, PS, DMS, DES, DMSO. The weight ratio can be A:B:C=0.1%-3.0%:0.5%-4.0%:1.0%-5.0%.

Abstract: This invention discloses a type of mixed additives for electrolyte of lithium-ion secondary batteries, having the following characteristics: in weight percentage: biphenyl series: 0.5% to 95.4%; cyclohexylbenzene series: 1.1% to 93.8%; vinylene carbonate: 0.4% to 93.2%; phenyl vinyl sulfone: 0.5% to 96.5%; ethenyl sulfonyl benzene: 0.5% to 95.8%. This invention also discloses an electrolyte for lithium-ion secondary batteries comprising organic solvents and lithium saline, wherein the special characteristic is that it comprises 2% to 20% weight percentage of said mixed additives. The distinctive advantage of the mixed additives for lithium-ion secondary batteries of this invention is to effectively enhance the overcharging, low-temperature, and cycle properties of lithium-ion batteries. A lithium-ion battery having the mixed additives of this invention remains explosion-free, ignition-free and reliably safe when the lithium-ion secondary battery is overcharging.

Abstract: Described are lithium iron phosphate cathode materials for lithium secondary batteries and methods of preparation thereof. Better cathode materials may be produced by two carbon processes. The first carbon process comprises mixing lithium compounds, iron compounds, phosphorous compounds and a first carbon additive, and heating the mixture to a first temperature. The second carbon process comprises adding a second carbon additive to the to the product of the first carbon process and heating the mixture to a second temperature. The cathode material so produced exhibits superior electrical properties.

Abstract: This invention relates to non-aqueous electrolytes, in particular, a non-aqueous electrolyte for lithium-ion secondary batteries. The electrolyte comprises regular organic solvents and electrolyte saline. The special characteristics are: the electrolyte also comprises mixed additives, said mixed additives comprising at least one of those of compound group A, at least one of those of compound group B, and one of those of compound group C wherein: compound group A are selected from inorganic saline including Li2CO3, Li2SO4, Li2 SO3, LiNO3; compound group B are selected from vinylene carbonate, propylene carbonate; and compound group C are selected from ES, PS, DMS, DES, DMSO. The weight ratio can be (Group I).

Abstract: Methods for preparing iron source material and ferrous oxalate for lithium ferrous phosphate are disclosed. One method comprises bringing solution containing ferrite and soluble non-ferrous metal salts in contact with oxalate solution; wherein said method of contact is to allow a flow of the ferrite solution containing ferrite and soluble non-ferrous metal salts to come in contact with a flow of oxalate solution. Another method comprises brings a stream of ferrite solution in contact with a stream of oxalate solution, wherein the flow rates of the ferrite solution and oxalate solution give the resulting slurry a pH of 2-6. The ferrous oxalate particles produces by the methods of the present invention are regularly shaped and have small and evenly distributed diameters.