Abstract: This application relates to a tab flattening device. The tab flattening device includes: a roller configured to convey an electrode plate, a cover, and a flattening portion. The surface of the roller is in contact with the electrode plate in a contact region. The cover surrounds the contact region peripherally and includes a feed-in guide surface oriented toward the contact region. The flattening portion is disposed protrusively on the feed-in guide surface, and located opposite to a tab of the electrode plate. A tab guide surface is formed on the flattening portion. Along a feed-in direction of the electrode plate, the flattening portion is at least partially located upstream of the contact region.

Abstract: Provided are a system for constructing a genome-wide sgRNA library and a use thereof. The system includes an input module, an sgRNA design module and an sgRNA filtering module. By constructing three modules in the system, optimizing details and processes in the modules, and adopting multiple design criteria and screening principles, the genome-wide sgRNA library is finally constructed. The system and method are concise and efficient, and the obtained library has a high quality and good activity, and is convenient for applications in gene editing researches.