Abstract: The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors.

Abstract: A gate drive unit includes a charging device, a switch, and a timing module. The charging device is conductively coupled with an electrical energy source and a power switch between the electric energy source and the charging device. The switch closes to transfer electrical energy from the energy source to the charging device. The timing module is configured to close the switch to direct the electrical energy from the electrical energy source to the charging device for a designated charging time period in order to charge the charging device with the electrical energy while the power switch is in an OFF state. The timing module opens the switch to cause the electrical energy stored in the charging device to be transferred out of the charging device in the form of a trigger current that is conducted to a gate terminal of the power switch to activate the power switch to an ON state from the OFF state.

Abstract: A system and method for conditioning DC power received from hybrid DC power sources is disclosed. A power conversion circuit is coupled to a respective DC power source to selectively condition the output power generated thereby to a DC bus voltage. The power conversion circuit includes a switch arrangement and capacitors arranged to provide a charge balancing in the power conversion circuit. A controller in operable communication with the switch arrangement receives inputs on a DC bus voltage and at least one parameter related to operation of the DC power source, and determines an adjustable voltage to be output from the conversion circuit to the DC bus based on the received inputs. The controller then selectively controls operation of the switch arrangement in order to generate the determined adjustable voltage.

Abstract: A power conversion system is presented. The power conversion system includes a power converter. The power converter includes at least two circuits, where each of the at least two circuits includes two or more phase legs, where each of the two or more phase legs includes at least two semiconductor switches. Also, the at least two circuits includes an interphase reactor configured to couple one of the two or more phase legs to at least one other phase leg in the two or more phase legs. Moreover, the power conversion system includes a controller configured to obtain a switching pattern for each of the at least two semiconductor switches of the at least two circuits and selectively switch each of the at least two semiconductor switches based on the obtained switching pattern to reduce a common mode signal in the power conversion system. Method for power conversion is also presented.

Abstract: A power conversion system is presented. The system includes a power source coupled to a power converter and a controller. The controller is configured to determine a value of at least one parameter corresponding to the power source. Additionally, the controller is configured to provide a first portion of the at least one parameter to the power converter and modify an operating frequency of the power converter, duty ratio of the power converter, or a combination thereof. Furthermore, the controller is configured to obtain an electrical quantity at an output of the power converter based on the modified operating frequency, the modified duty ratio, or a combination thereof. Also, the controller is configured to deliver a combination of the electrical quantity obtained at the output of the power converter and a second portion of the at least one parameter to a load. Method for converting power is also presented.

Abstract: A portable x-ray system includes a light weight x-ray head including an x-ray tube and a high voltage (HV) tank, wherein the HV tank comprises a compact voltage multiplier configured to receive a low voltage signal and generate a high voltage signal based on the received low voltage signal. Also, the portable x-ray system includes a carrying case comprising low voltage power electronics coupled to the light weight x-ray head through a low voltage cable, and configured to send the low voltage signal to the light weight x-ray head. In addition, the low voltage power electronics is distributed in a predefined space in the carrying case in such a way that a weight of the light weight x-ray head is counter weighed by a weight of the low voltage power electronics to stabilize the portable x-ray system when the light weight x-ray head is rotated in one or more directions.

Abstract: A motion correction system and method for motion correction for an x-ray tube is presented. One embodiment of the motion correction system includes a sensing unit coupled to an x-ray tube to determine a distance with which an impingement location of an electron beam generated by the x-ray tube deviates from a determined location due to motion of the x-ray tube. The motion correction system further includes a control unit coupled to the sensing unit to generate a control signal corresponding to the distance with which the impingement location of the electron beam deviates. Also, the motion correction system includes a deflection unit coupled to the control unit to steer the electron beam to the determined location based on the generated control signal.

Abstract: A gate drive circuit includes an insulated gate semiconductor switch. A controlled current source is connected to the semiconductor switch gate terminal to provide a gate drive circuit that is responsive to recycled gate charge corresponding to an internal gate capacitance of the insulated gate semiconductor switch.

Abstract: A power converter is provided. The power converter includes a converter leg including switches for converting power. The power converter also includes a controller for switching the switches using a pulse width modulation technique. The power converter further includes an interface inductor coupled to the converter leg for avoiding a reverse recovery of current in the switches during operation.

Abstract: The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors.

Abstract: An apparatus and method for providing a predefined x-ray field is presented. Briefly in accordance with one aspect of the present disclosure, the apparatus includes a cathode unit configured to emit electrons within a vacuum chamber. The apparatus further includes an anode unit configured to generate x-rays when the emitted electrons impinge on a target surface of the anode unit. Also, the apparatus includes a collimating unit comprising a primary set of blades disposed in the vacuum chamber at a first distance from the anode unit for collimating the generated x-rays to provide the predefined x-ray field at a detector.

Abstract: A motion correction system and method for motion correction for an x-ray tube is presented. One embodiment of the motion correction system includes a sensing unit coupled to an x-ray tube to determine a distance with which an impingement location of an electron beam generated by the x-ray tube deviates from a determined location due to motion of the x-ray tube. The motion correction system further includes a control unit coupled to the sensing unit to generate a control signal corresponding to the distance with which the impingement location of the electron beam deviates. Also, the motion correction system includes a deflection unit coupled to the control unit to steer the electron beam to the determined location based on the generated control signal.

Abstract: A power generator includes one or more full bridge inverter modules coupled to a semiconductor opening switch (SOS) through an inductive resonant branch. Each module includes a plurality of switches that are switched in a fashion causing the one or more full bridge inverter modules to drive the semiconductor opening switch SOS through the resonant circuit to generate pulses to a load connected in parallel with the SOS.

Abstract: An x-ray tube is presented. One embodiment of the x-ray tube includes a cathode unit configured to emit electrons. The x-ray tube further includes an anode unit positioned to receive the emitted electrons, wherein the anode unit includes a base having a target surface configured to generate x-rays when the emitted electrons impinge on the target surface. Also, the anode unit includes a first shielding unit enclosing the base to attenuate at least a first portion of the generated x-rays within the anode unit.

Abstract: Systems, apparatus, and program product and methods for controlling boundary layer flow across an aerodynamic structure which can produce separate regions of flow structures at different strengths by means of dielectric-barrier-discharge (DBD) type plasmas, are provided. An example of such apparatus provides plasma regions that are capable of being individually controlled by voltage and/or frequency, and modulated for the purposes of flow control. The apparatus includes an electrode assembly fitted with electrodes on either side of a dielectric such that different electrode geometries and arrangements create isolated regions of plasmas which results in separate regions of flow structures. These regions may be further controlled and modulated by the use of electronic-switching to produce irregularly shaped flow structures and strengths including those having a primarily vertical component.

Abstract: A novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors.

Abstract: A gate drive circuit includes an insulated gate semiconductor switch. A controlled current source is connected to the semiconductor switch gate terminal to provide a gate drive circuit that is responsive to recycled gate charge corresponding to an internal gate capacitance of the insulated gate semiconductor switch.

Abstract: A power generator includes one or more full bridge inverter modules coupled to a semiconductor opening switch (SOS) through an inductive resonant branch. Each module includes a plurality of switches that are switched in a fashion causing the one or more full bridge inverter modules to drive the semiconductor opening switch SOS through the resonant circuit to generate pulses to a load connected in parallel with the SOS.

Abstract: A power converter utilizes one or more nonlinear composite film capacitors constructed solely of polymer anti-ferroelectric (AFE) particle composites and configured as DC-link bus capacitors providing an energy buffer to reduce DC-link voltage ripple.

Abstract: Systems, apparatus, and program product and methods for controlling boundary layer flow across an aerodynamic structure which can produce separate regions of flow structures at different strengths by means of dielectric-barrier-discharge (DBD) type plasmas, are provided. An example of such apparatus provides plasma regions that are capable of being individually controlled by voltage and/or frequency, and modulated for the purposes of flow control. The apparatus includes an electrode assembly fitted with electrodes on either side of a dielectric such that different electrode geometries and arrangements create isolated regions of plasmas which results in separate regions of flow structures. These regions may be further controlled and modulated by the use of electronic-switching to produce irregularly shaped flow structures and strengths including those having a primarily vertical component.