Patents by Inventor Fenghe Du

Fenghe Du has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mule: Mcl-1 ubiquitination ligase E3
    Patent number: 7303887
    Abstract: A HECT-domain containing E3 ubiquitin ligase that mediates the polyubiquitination of Mcl-1, named Mule for Mcl-1 ubiquitin ligase E3, is described. Methods and compositions for modulating functional interaction between Mcl-1 and Mule protein and Mcl-1 mediated apoptosis are described. Diagnostic and prognostic methods based on Mule expression in patient cells are also described.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: December 4, 2007
    Assignee: Board of Regents, The University of Texas System
    Inventors: Xiaodong Wang, Qing Zhong, Wenhua Gao, Fenghe Du
  • Mule: Mcl-1 ubiquitination ligase E3
    Publication number: 20060264366
    Abstract: A HECT-domain containing E3 ubiquitin ligase that mediates the polyubiquitination of Mcl-1, named Mule for Mcl-1 ubiquitin ligase E3, is described. Methods and compositions for modulating functional interaction between Mcl-1 and Mule protein and Mcl-1 mediated apoptosis are described. Diagnostic and prognostic methods based on Mule expression in patient cells are also described.
    Type: Application
    Filed: May 18, 2005
    Publication date: November 23, 2006
    Inventors: Xiaodong Wang, Qing Zhong, Wenhua Gao, Fenghe Du