Abstract: This disclosure provides an unmanned survey vessel with an anti-overturning structure and an anti-overturning method of same, and relates to the anti-overturning technique field of unmanned survey vessels. The unmanned survey vessel includes a vessel body and a plurality of buoys. The vessel body is a hollow frame of which a middle is provided with a discharge space. An uptight rod is vertically fixed at an upper-end of the tail part of the vessel body. A supporting beam is horizontally fixed at an upper-end of the upright rod. The supporting beam extends to a bow of the vessel. A rectangular notch is formed in one end, close to the bow, of the supporting beam. One end close to the bow inside the rectangular notch is rotatably provided with a guide rod through a pin shaft. The plurality of buoys are equally divided into two groups which are adjustably arranged on two side walls in the advancing direction of the vessel body respectively.

Abstract: An easy-to-assemble mounting rack for a deformation detection device for a steel structure and an assembling method thereof are provided. The easy-to-assemble mounting rack includes mounting parts including a back mounting plate, an operating rod, an adjusting seat, a ball-shaped block and an upright rod. The upright rod is vertically fixed at the bottom end face of the adjusting seat. A ball-shaped hole is formed in the adjusting seat. The ball-shaped block is rotatably embedded in the ball-shaped hole. A plug-in hole is formed in a radial direction of the ball-shaped block. One end of the operating rod slidably penetrates through the plug-in hole and is detachably connected with the back mounting plate. Screw holes directly opposite to the mounting holes of the deformation detection device are formed on the back mounting plate. The other end of the operating rod is fixedly sleeved with a counterweight plate.

Abstract: Example inventions detect and treat an occurrence of an apnea event during a sleep period of a user. Example inventions receive data corresponding to nasal air pressure of the user and/or audio of the user during the sleep period. Example inventions determine patterns in the data, based on the patterns, detect the apnea event and, in response to the detecting, treat the apnea event.

Abstract: Compounds, including Toll-like receptor (TLR) agonists, e.g., TLR7 and TLR7/8 agonists and their folic acid or pteroyl amino acid conjugates, and use thereof to treat a cancer or a fibrotic disease or disorder; and methods of making conjugates comprising targeting ligands of folic acid receptor and TLR7 and TLR7/8 agonists.

Abstract: The present invention relates to a preparation method for and an application of a chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand SpiroPNP and an iridium catalyst Ir-SpiroPNP thereof. The chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand is a compound represented by formula I, or a racemate or optical isomer thereof, or a catalytically acceptable salt thereof, and the main structural feature is a phosphine ligand having a chiral spiro indene skeleton and a large sterically hindered substituent. The chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand can be synthesized into a chiral starting material from a 7-diaryl/alkylphosphino-7?-amino-1,1?-spirodihydroindenyl compound having a spiro ring skeleton. The iridium catalyst of the chiral spirocyclic phosphino-7?-amino-1,1?-spirodihydroindenyl compound having a sprio ring skeleton.

Abstract: Compounds, pharmaceutical compositions and methods are provided for reprogramming M2-like macrophages to M1-like macrophages, which reverses the antifibrotic to profibrotic shift observed during the course of fibrotic diseases and certain cancers. The compounds comprise an immune modulator that targets a pattern recognition receptor of a cell and are specific to the cells of interest through the incorporation of a targeting moiety (e.g., folate or a functional fragment or analog thereof). Releasable and/or non-releasable linkers can be included and engineered to facilitate the optimal delivery of the immune modulator. The compounds and compositions can be employed in one or more methods of treatment for fibrotic diseases and/or cancers.

Abstract: A wiring apparatus for a communication pipeline includes a frame and wheels arranged on the frame in pairs. A control motor for driving the wheels to rotate is arranged on the frame, at least one pair of wheels are rotatably connected to the frame, a recessed wire clamping cavity is arranged on an outer peripheral of the wheel, a channel configured for clamping an optical power cable is formed between two wheels arranged in pairs through the wire clamping cavity, and a hook (on which a wiring can be hung) is arranged at an end of the frame.

Abstract: Disclosed relates to an electrochemical determination system of glycated proteins, the system comprising: a filtering means for filtering labeled compounds bound to glycated proteins and non-glycated proteins after adding labeling compounds, capable of selectively binding to the glycated proteins to a solution, in which glycated/non-glycated proteins coexist, to be bound all to the glycated proteins; and a quantifying means for quantifying the filtered labeling compounds, not bound to the glycated proteins. The system of the present invention filters the residual labeled compounds left after binding to glycated proteins to quantify, instead of directly quantifying glycated proteins via the known glycated protein determination methods, thus simplifying the configuration of the system that can provide exact determinations with a low cost.

Abstract: Disclosed relates to an electrochemical determination system of glycated proteins, the system comprising: a filtering means for filtering labeled compounds bound to glycated proteins and non-glycated proteins after adding labeling compounds, capable of selectively binding to the glycated proteins to a solution, in which glycated/non-glycated proteins coexist, to be bound all to the glycated proteins; and a quantifying means for quantifying the filtered labeling compounds, not bound to the glycated proteins. The system of the present invention filters the residual labeled compounds left after binding to glycated proteins to quantify, instead of directly quantifying glycated proteins via the known glycated protein determination methods, thus simplifying the configuration of the system that can provide exact determinations with a low cost.

Abstract: A biosensor, for use in measurement of an analyte, includes a microporous membrane support, a first electrode system, a second electrode system, and a pair of insulating films. The first electrode system is formed on the surface of the microporous membrane support and the second electrode system is formed on the opposite surface of the microporous membrane support. The biosensor enables a rapid, simple, separation-free, and selective detection of the analytes. The biosensor does not require any bulky additional electrode, so that miniaturization, point-of-car testing, and disposability can be achieved.

Abstract: A biosensor, for use in measurement of an analyte, includes a microporous membrane support, a first electrode system, a second electrode system, and a pair of insulating films. The first electrode system is formed on the surface of the microporous membrane support and the second electrode system is formed on the opposite surface of the microporous membrane support. The biosensor enables a rapid, simple, separation-free, and selective detection of the analytes. The biosensor does not require any bulky additional electrode, so that miniaturization, point-of-car testing, and disposability can be achieved.