Patents by Inventor Fengkai CHENG

Fengkai CHENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC DERIVATIVE PARP INHIBITOR AND USE THEREOF
    Publication number: 20240391937
    Abstract: Disclosed are a compound as shown in formula (I), a stereoisomer, pharmaceutically acceptable salt, solvate, cocrystal or deuterated compound thereof, or a pharmaceutical composition containing same, and the use thereof as a PARP-1 inhibitor in the preparation of a drug for treating related diseases, wherein the definition of each group in formula (I) is as defined in the description.
    Type: Application
    Filed: September 30, 2022
    Publication date: November 28, 2024
    Inventors: Yao LI, Wenjing WANG, Lei CHEN, Peng KANG, Chao FU, Fengkai CHENG, Pingming TANG, Yan YU, Chen ZHANG, Pangke YAN
  • AAK1 INHIBITOR AND USE THEREOF
    Publication number: 20240343720
    Abstract: A compound of formula (I) and a stereoisomer, deuterated compound, solvate, prodrug, metabolite, pharmaceutically acceptable salt or co-crystal thereof, or a pharmaceutical composition containing same, and the use thereof as an AAK1 inhibitor in the preparation of a drug for treating related diseases.
    Type: Application
    Filed: July 14, 2022
    Publication date: October 17, 2024
    Inventors: Yao Li, Wenjing Wang, Zongjun Shi, Haoliang Zhang, Chenglong Du, Fengkai CHENG, Xin Liu, Xiaozhuan Zhang, Long Wang, Pingming Tang, Yan Yu, Chen Zhang, Pangke Yan
  • PYRIDINE OXYNITRIDE, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230303495
    Abstract: The present invention belongs to the field of medicinal chemistry. Disclosed are a pyridine oxynitride, a preparation method therefor and the use thereof. Specifically, the present invention relates to a series of sodium ion channel blockers with a new structure, a preparation method therefor and the use thereof. The structure thereof is as shown in general formula (I) below. The compounds or a stereoisomer, a racemate, a geometric isomer, a tautomer, a prodrug, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof and a pharmaceutical composition can be used for treating or/and preventing related diseases mediated by a sodium ion channel (NaV).
    Type: Application
    Filed: September 11, 2020
    Publication date: September 28, 2023
    Inventors: Qiong ZHANG, Zhongli WANG, Ming DAI, Fengkai CHENG, Jiu LUO, Yan YE, Jianbiao PENG, Haibing GUO
  • PYRIDINE OXYNITRIDE, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230026907
    Abstract: The present invention belongs to the field of medicinal chemistry. Disclosed are a pyridine oxynitride, a preparation method therefor and the use thereof. Specifically, the present invention relates to a series of sodium ion channel blockers with a new structure, a preparation method therefor and the use thereof. The structure thereof is as shown in general formula (I) below. The compounds or a stereoisomer, a racemate, a geometric isomer, a tautomer, a prodrug, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof and a pharmaceutical composition can be used for treating or/and preventing related diseases mediated by a sodium ion channel (NaV).
    Type: Application
    Filed: September 11, 2020
    Publication date: January 26, 2023
    Inventors: Qiong ZHANG, Zhongli WANG, Ming DAI, Fengkai CHENG, Jiu LUO, Yan YE, Jianbiao PENG, Haibing GUO