Patents by Inventor Fengying Guo

Fengying Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11434212
    Abstract: A compound represented by formula (I), a pharmaceutically acceptable salt or tautomer thereof, and an application of the compound as a caspase inhibitor.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: September 6, 2022
    Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Jianfeng Mou, Songliang Wu, Haiying He, Fengying Guo, Chuan Wang, Jie Li, Jian Li, Shuhui Chen
  • Publication number: 20220098178
    Abstract: The present invention relates to a preparation method for an amide compound and an application thereof in the field of medicine. Specifically, provided by the present invention is an amide small molecule compound which is an inhibitor of Zeste gene enhancer homolog 2 (EZH2) and which may be used to prevent and/or treat EZH2-mediated related diseases, comprising tumors, myeloproliferative diseases or autoimmune diseases.
    Type: Application
    Filed: March 24, 2020
    Publication date: March 31, 2022
    Inventors: Xin XU, Jia CHEN, Zhen ZHANG, Liming ZHANG, Qimei WU, Qingyun JIANG, Fengying GUO, Yuyun ZHANG, Hao YU, Ying WANG, Kang SUN, Chengxu ZANG, Chenggang QIN, Xiaobo ZHOU, Xiaojuan ZHANG, Yijin WANG, Xiaoer XIA, Yunfei LI, Jian GE
  • Publication number: 20220024941
    Abstract: Provided are a preparation method for amide compounds and use thereof in medical field. Specifically, provided are small molecule amide compounds. Such compounds are inhibitors of enhancer homolog 2 (EZH2) of Zeste gene, and can be used for preventing and/or treating related diseases mediated by EZH2, including tumors, myeloproliferative diseases or autoimmune diseases.
    Type: Application
    Filed: March 24, 2020
    Publication date: January 27, 2022
    Inventors: Xin XU, Jia CHEN, Zhen ZHANG, Liming ZHANG, Qimei WU, Qingyun JIANG, Fengying GUO, Yuyun ZHANG, Hao YU, Xiaojuan ZHANG, Kang SUN, Xiaobo ZHOU, Chengxu ZANG, Yijin WANG, Xiaoer XIA, Yunfei LI, Jian GE
  • Publication number: 20210332019
    Abstract: A compound represented by formula (I), a pharmaceutically acceptable salt or tautomer thereof, and an application of the compound as a caspase inhibitor.
    Type: Application
    Filed: January 23, 2018
    Publication date: October 28, 2021
    Inventors: Jianfeng MOU, Songliang WU, Haiying HE, Fengying GUO, Chuan WANG, Jie LI, Jian LI, Shuhui CHEN
  • Patent number: 11072601
    Abstract: Disclosed are a class of ?-opioid receptor agonists and a preparation method therefor and the use thereof in the field of medicine, belonging to the field of medicinal chemistry. The ?-opioid receptor agonists significantly increase the selectivity for a G protein signaling pathway, and not only can exhibit excellent pharmacodynamic effects, but also significantly improve safety.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: July 27, 2021
    Assignees: SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD., ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.
    Inventors: Xin Xu, Zhen Zhang, Yunfei Li, Liming Zhang, Fengying Guo, Qingyun Jiang, Dongsheng Li, Linli Zhang, Jinqian Song, Lei Liu, Qiang Liu, Jing Su, Yijin Wang, Jian Ge
  • Patent number: 10981860
    Abstract: Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: April 20, 2021
    Assignees: Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Medshine Discovery Inc.
    Inventors: Haiying He, Songliang Wu, Zhi Luo, Jianfeng Mou, Fengying Guo, Chuan Wang, Guoqing Li, Minggao Zeng, Shuhui Chen
  • Publication number: 20200270230
    Abstract: Disclosed are a class of ?-opioid receptor agonists and a preparation method therefor and the use thereof in the field of medicine, belonging to the field of medicinal chemistry. The ?-opioid receptor agonists significantly increase the selectivity for a G protein signaling pathway, and not only can exhibit excellent pharmacodynamic effects, but also significantly improve safety.
    Type: Application
    Filed: September 17, 2018
    Publication date: August 27, 2020
    Inventors: Xin Xu, Zhen Zhang, Yunfei Li, Liming Zhang, Fengying Guo, Qingyun Jiang, Dongsheng Li, Linli Zhang, Jinqian Song, Lei Liu, Qiang Liu, Jing Su, Yijin Wang, Jian Ge
  • Publication number: 20190135733
    Abstract: Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.
    Type: Application
    Filed: May 11, 2017
    Publication date: May 9, 2019
    Inventors: Haiying He, Songliang Wu, Zhi Luo, Jianfeng Mou, Fengying Guo, Chuan Wang, Guoqing Li, Minggao Zeng, Shuhui Chen