Abstract: The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.

Abstract: The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.

Abstract: The present disclosure provides compositions having reduced viscosity which may be used as adhesives or tissue sealants, and includes methods for speeding the cure rate of such compositions.

Abstract: The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.

Abstract: Surgical sutures capable of forming a chemical knot include a first reactive member on a first portion thereof and a second reactive member on a second portion thereof, wherein the first and second reactive members are complimentary.

Abstract: At least one aspect of this disclosure includes a system for closing an aperture in a biological tissue, the system comprising a handle, an elongate shaft connected to the handle, a deployment scaffold connected to the shaft, the deployment scaffold comprising a frame and a plurality of deployment arms hingedly connected to the frame, wherein the frame is configured to move from a retained position to at least one deployed position, a plurality of clips connected to the arms, wherein the clips are configured to releasably retain a surgical implant, and at least one sleeve selectively disposed at least partially over at least one of the plurality of arms when the frame is in the retained position, and selectively exposing at least one of the clips in the deployed position.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Abstract: Implantable biocompatible polymeric medical devices include a substrate with a plasma-modified surface which is subsequently modified to include click reactive members.

Abstract: Colored high-strength fibers of ultra-high-molecular-weight polyolefins and methods of dyeing the high-strength fibers are disclosed herein.

Abstract: The present disclosure provides coatings for filaments that enhance the resistance of a filament to cuts and/or abrasions. Depending upon the material utilized to form the filament to be coated, the appropriate coating in the appropriate amount may be selected to coat the filament thereby imparting resistance to abrasions and cuts to the filament. The resulting filament may be utilized to form filamentous devices including sutures and meshes.

Abstract: The present disclosure provides coatings for filaments that enhance the resistance of a filament to cuts and/or abrasions. Depending upon the material utilized to form the filament to be coated, the appropriate coating in the appropriate amount may be selected to coat the filament thereby imparting resistance to abrasions and cuts to the filament. The resulting filament may be utilized to form filamentous devices including sutures and meshes.

Abstract: Methods for producing biocompatible compositions are provided. The biocompatible compositions include an isocyanate-functional polyurethane prepolymer in combination with a foam control agent. The foam control agent decreases the formation of bubbles and/or foam in the biocompatible composition, thereby enhancing the physical properties of the biocompatible composition. The presence of the foam control agent does not compromise the strength of the biocompatible composition. The compositions prepared by the methods of the present disclosure may be used as adhesives or sealants for medical/surgical uses.

Abstract: Biocompatible compositions are provided which may include at least one polysaccharide, at least one salt, and at least one reactive component. The at least one polysaccharide, at least one salt, and at least one reactive component may be in a single solution or multiple solutions and combined utilizing means within the purview of those skilled in the art. The compositions of the present disclosure experience delayed gelation, permitting their manipulation after application to tissue, which may be desirable for certain surgical and/or medical procedures, including cosmetic surgery.

Abstract: Biocompatible implants include a polymer substrate and a reactive component selectively applied to the substrate. The reactive component in combination with the substrate creates crosslinked regions on a surface of the substrate. The crosslinked regions may provide a visual aid and/or stiffening element to the implant.

Abstract: The present disclosure describes a coating for a surgical suture including a vinyl lactam polymer and a lactone polymer.

Abstract: The present disclosure relates to a filament for use in surgical procedures. The filament includes a first end with a first tangible indicator and a second end with a second, different tangible indicator. The first and second tangible indicators attribute different surface topographies to the respective first and second ends of the filament to provide a way of differentiating therebetween through tactile engagement.

Abstract: Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic functional groups capable of reacting and crosslinking in situ. Methods for making the resulting biocompatible crosslinked polymers biodegradable, or not, are provided, as are methods for controlling the rate of degradation. The crosslinking reactions may be carried out in situ on organs or tissues or outside the body. In embodiments, the biocompatible crosslinked polymers and/or their precursors may be utilized in a surgical procedure, such as a polypectomy.

Abstract: Compounds are provided which can form bioabsorbable compositions useful as adhesives or sealants for medical/surgical applications.

Abstract: The present disclosure provides compositions having reduced viscosity which may be used as adhesives or tissue sealants, and includes methods for speeding the cure rate of such compositions.

Abstract: The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.