Patents by Inventor Ferdinand Jacobus MILDER

Ferdinand Jacobus MILDER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Influenza virus vaccines and uses thereof
    Patent number: 11905314
    Abstract: Provided herein are influenza hemagglutinin stem polypeptides, nucleic acids encoding said polypeptides, vectors comprising said nucleic acid and pharmaceutical compositions comprising the same, as well as methods of their use, in particular in the prevention and/or treatment of influenza virus infections.
    Type: Grant
    Filed: July 26, 2022
    Date of Patent: February 20, 2024
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Ferdinand Jacobus Milder, Tina Ritschel, Boerries Brandenburg, Mandy Antonia Catharina Jongeneelen, Daphné Truan, Johannes Petrus Maria Langedijk
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20230312654
    Abstract: Provided herein are isolated mutant influenza hemagglutinin polypeptides, methods for providing isolated mutant hemagglutinin polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza.
    Type: Application
    Filed: October 15, 2020
    Publication date: October 5, 2023
    Inventors: Boerries BRANDENBURG, Johannes Petrus Maria LANGEDIJK, Tina RITSCHEL, Ferdinand Jacobus MILDER, Mandy Antonia Catharina JONGENEELEN
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20230250135
    Abstract: Provided herein are group 2 influenza hemagglutinin stem polypeptides, nucleic acids encoding said polypeptides, vectors comprising said nucleic acid and pharmaceutical compositions comprising the same, as well as methods of their use, in particular in the prevention and/or treatment of influenza virus infections.
    Type: Application
    Filed: September 3, 2020
    Publication date: August 10, 2023
    Inventors: Mandy Antonia Catharina JONGENEELEN, Tina RITSCHEL, Ferdinand Jacobus MILDER, Indigo KING, Yifan SONG, Johannes Petrus Maria LANGEDIJK, Boerries BRANDENBURG
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20220411474
    Abstract: Provided herein are influenza hemagglutinin stem polypeptides, nucleic acids encoding said polypeptides, vectors comprising said nucleic acid and pharmaceutical compositions comprising the same, as well as methods of their use, in particular in the prevention and/or treatment of influenza virus infections.
    Type: Application
    Filed: July 26, 2022
    Publication date: December 29, 2022
    Inventors: Ferdinand Jacobus Milder, Tina Ritschel, Boerries Brandenburg, Mandy Antonia Catharina JONGENEELEN, Daphné Truan, Johannes Petrus Maria Langedijk
  • Influenza virus vaccines and uses thereof
    Patent number: 11447526
    Abstract: Provided herein are influenza hemagglutinin stem polypeptides, nucleic acids encoding said polypeptides, vectors comprising said nucleic acid and pharmaceutical compositions comprising the same, as well as methods of their use, in particular in the prevention and/or treatment of influenza virus infections.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: September 20, 2022
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Ferdinand Jacobus Milder, Tina Ritschel, Boerries Brandenburg, Mandy Antonia Catharina Jongeneelen, Daphné Truan, Johannes Petrus Maria Langedijk
  • RECOMBINANT INFLUENZA ANTIGENS
    Publication number: 20220204567
    Abstract: The invention provides recombinant influenza A hemagglutinin (HA) polypeptides, comprising an HA1 and a HA2 domain of an influenza A virus HA, and comprising an amino acid sequence wherein: (a) the amino acid at position 355 is W; and (b) the amino acid at position 432 is I and/or the amino acid at position 380 is I; and wherein the numbering of the amino acid positions in the amino acid sequence of the HA polypeptide is according to the numbering of amino acids in the amino acid sequence of HA from a reference H3N2 influenza strain, in particular the reference strain H3N2 A/Aichi/2/68 (SEQ ID NO: 1), immunogenic fragments thereof, nucleic acid molecules encoding said polypeptides or immunogenic fragments, and uses thereof.
    Type: Application
    Filed: April 23, 2020
    Publication date: June 30, 2022
    Inventors: Boerries BRANDENBURG, Tina RITSCHEL, Ferdinand Jacobus MILDER, Mandy Antonia, Catharina JONGENEELEN, Indigo KING, Yifan SONG, Johannes Petrus, Maria LANGEDIJK
  • INFLUENZA VIRUS VACCINES AND USES THEREOF
    Publication number: 20200377555
    Abstract: Provided herein are influenza hemagglutinin stem polypeptides, nucleic acids encoding said polypeptides, vectors comprising said nucleic acid and pharmaceutical compositions comprising the same, as well as methods of their use, in particular in the prevention and/or treatment of influenza virus infections.
    Type: Application
    Filed: January 22, 2019
    Publication date: December 3, 2020
    Inventors: Ferdinand Jacobus MILDER, Tina RITSCHEL, Boerries BRANDENBURG, Mandy Antonia Catharina JONGENEELEN, Daphné TRUAN, Johannes Petrus Maria LANGEDIJK