Abstract: A scaffold for tissue regeneration, particularly for bone regeneration, comprises a three-dimensional supporting structure made of a biocompatible and biodegradable material; the supporting structure is functionalized with secretome, in particular mesenchymal stem cell secretome, preferably in lyophilized form (lyosecretome).

Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.

Abstract: A structure has a plurality of modules of cementitious material; a first module exhibiting a reciprocal coupling surface and hooking portions defining at least one cavity, a second module exhibiting a respective reciprocal coupling surface—countershaped and in contact with the reciprocal coupling surface of the first module—and a hooking portion defining at least one cavity extending along at least partially the stratification direction; a connecting element engaged, on one side, inside the cavity of the hooking portion of the first module and, on the other side, inside the cavity of the hooking portion of the second module. The connecting element is configured for stably constraining the first and second modules and holding these latter in contact with each other. Further, a process makes a structure of reinforced cementitious material.

Abstract: A structure has a plurality of modules of cementitious material; a first module exhibiting a reciprocal coupling surface and hooking portions defining at least one cavity, a second module exhibiting a respective reciprocal coupling surface—countershaped and in contact with the reciprocal coupling surface of the first module—and a hooking portion defining at least one cavity extending along at least partially the stratification direction; a connecting element engaged, on one side, inside the cavity of the hooking portion of the first module and, on the other side, inside the cavity of the hooking portion of the second module. The connecting element is configured for stably constraining the first and second modules and holding these latter in contact with each other. Further, a process makes a structure of reinforced cementitious material.

Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].

Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.

Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.

Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.

Abstract: The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.