Abstract: A method for determining a region for safe placement of a device in a medical image includes receiving a medical image, detecting at least one anatomic landmark in the medical image using at least one deep convolutional neural network, determining the region for safe placement of the device based on the detected at least one anatomic region using a semantic network, and displaying the region for safe placement of a device on the medical image using a display.

Abstract: The present invention includes devices, systems, and methods for sealing a defect in body tissue. For example, the present invention includes a device for preventing leakage of air and other gases from the lung during and after lung biopsy. The device delivers a hydrogel composition which forms an air-tight sealant. In certain embodiments, the device simultaneously delivers one or more therapeutic agents, such as lidocaine, to the treatment area.